Victoria E. Watson
A5007769921- Infant Development and Preterm Care
- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Microbial infections and disease research
- Veterinary Oncology Research
- Neonatal and fetal brain pathology
- Drug Transport and Resistance Mechanisms
- Escherichia coli research studies
- Breastfeeding Practices and Influences
- Peroxisome Proliferator-Activated Receptors
- Enterobacteriaceae and Cronobacter Research
- Birth, Development, and Health
- Gut microbiota and health
- Child Nutrition and Feeding Issues
- Viral gastroenteritis research and epidemiology
- Veterinary Equine Medical Research
- Clostridium difficile and Clostridium perfringens research
- Infectious Diseases and Mycology
- Metabolism and Genetic Disorders
- Neuroscience of respiration and sleep
- Mycobacterium research and diagnosis
- Congenital Diaphragmatic Hernia Studies
- Veterinary Pharmacology and Anesthesia
- Lymphatic Disorders and Treatments
- Vascular Malformations and Hemangiomas
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2021-2024
Research Network (United States)
2021-2024
Michigan State University
2019-2024
Clinical Trial Investigators
2024
Duke University
2023
Health and Human Development (2HD) Research Network
2023
Brown University
2018-2022
Women & Infants Hospital of Rhode Island
2018-2022
University of Georgia
2010-2021
Indiana University – Purdue University Indianapolis
2020
Despite improvement during recent decades, extremely preterm infants continue to contribute disproportionately neonatal mortality and childhood morbidity. To review survival, in-hospital morbidities, care practices, neurodevelopmental functional outcomes at 22-26 months' corrected age for infants. Prospective registry born 19 US academic centers that are part of the Eunice Kennedy Shriver National Institute Child Health Human Development Neonatal Research Network. The study included 10 877...
Importance Maternal milk feeding of extremely preterm infants during the birth hospitalization has been associated with better neurodevelopmental outcomes compared formula. For receiving no or minimal maternal milk, it is unknown whether donor human conveys similar advantages vs Objective To determine if nutrient-fortified, pasteurized improves at 22 to 26 months’ corrected age infant formula among who received milk. Design, Setting, and Participants Double-blind, randomized clinical trial...
Importance Meta-analyses suggest that corticosteroids may be associated with increased survival without cerebral palsy in infants at high risk of bronchopulmonary dysplasia (BPD) but are adverse neurologic outcomes low-risk infants. Whether this association exists contemporary practice is uncertain because most randomized clinical trials administered earlier and higher doses than currently recommended. Objective To evaluate whether the pretreatment death or grade 2 3 BPD 36 weeks’...
<h3>Importance</h3> Both preterm birth and increased screen time are known to be associated with an increase in risk of developmental behavioral sequelae. The association between high or a television computer the bedroom early school age adverse cognitive, executive function, language, behavior outcomes extremely children (EPT) is not well understood. <h3>Objective</h3> To assess cognition, EPT aged 6 7 years; second objective was examine rates structured physical activity weight....
ABSTRACT Diarrhea is responsible for the death of approximately 900,000 children per year worldwide. In children, typical enteropathogenic Escherichia coli (EPEC) a common cause diarrhea and associated with higher hazard death. Typical EPEC infection rare in animals poorly reproduced experimental animal models. contrast, atypical (aEPEC) both animals, but its role uncertain. Mortality kittens often attributed to diarrhea, we previously identified enteroadherent intestines deceased kittens....
Bile acids (BAs) are steroid detergents in bile that contribute to fat absorption, cell signaling, and microbiome interactions. The final step their synthesis is amino acid conjugation with either glycine or taurine the liver by enzyme acid-CoA:amino N-acyltransferase (BAAT). Here, we describe microbial, chemical, physiological consequences of Baat gene knockout. Baat-/- mice were underweight after weaning but quickly exhibited catch-up growth. At three weeks age, KO animals had increased...
Importance Late-onset meningitis (LOM) has been associated with adverse neurodevelopmental outcomes in children born extremely preterm. Objective To report the incidence of LOM during birth hospitalization and at 18 to 26 months’ corrected age. Design, Setting, Participants This cohort study is a secondary analysis multicenter prospective 22 weeks’ gestation between 2003 2017 follow-up from 2004 2021. The was conducted 25 Eunice Kennedy Shriver National Institute Child Health Human...
Importance Extremely preterm infants who develop bronchopulmonary dysplasia (BPD) are at a higher risk for adverse pulmonary and neurodevelopmental outcomes. In the National Institute of Child Health Human Development Neonatal Research Network (NICHD NRN) Hydrocortisone Trial, hydrocortisone neither reduced rates BPD or death nor increased impairment (NDI) death. Objective To determine whether estimated grades 2 to 3 is associated with effect on composite outcomes (1) (2) moderate severe NDI...
Importance Redirection of care refers to withdrawal, withholding, or limiting escalation treatment. Whether maternal social determinants health are associated with redirection discussions merits understanding. Objective To examine associations between and for infants born extremely preterm. Design, Setting, Participants This is a retrospective analysis prospective cohort at less than 29 weeks’ gestation April 2011 December 2020 19 National Institute Child Health Human Development Neonatal...
Oligodendroglioma is one of the most common primary central nervous system neoplasms dogs. It often diagnosed in older, brachycephalic breeds, and although its typical clinical features neuroanatomic location have been well described, less presentations may hinder diagnosis. We describe 3 cases canine cerebral oligodendroglioma that clinically grossly present as intraventricular tumors. Histologic findings all were oligodendroglioma. Neoplastic cells uniformly immunoreactive for Olig2...
Background Lipogranulomatous lymphangitis is inflammation of the intestinal lymphatic vessels and surrounding tissues caused by chronic leakage lipid‐laden chyle. Grossly, lipogranulomas are typically disseminated small masses on serosa consist epithelioid macrophages, multinucleated giant cells, cholesterol. occasionally seen in patients with lymphangiectasia protein‐losing enteropathy ( PLE ). Objectives To characterize historical features, clinical signs, treatment, histopathology,...
Retrobulbar neoplasms are not common in mammals and even more infrequently seen nonmammalian species. The current report describes a retrobulbar mass creating exophthalmia neurologic signs red-lored Amazon parrot ( Amazona autumnalis). A 27-year-old female presented for 3-day history of anorexia 2-week periocular soft tissue swelling the right eye. Physical examination revealed 9% dehydration eye with inability to retropulse globe. fine-needle aspirate was performed, cytologic evaluation...
ABSTRACT Bile acids are steroid detergents in bile that contribute to fat absorption, cell signaling and microbiome interactions mammals. The final step their synthesis is amino acid conjugation with either glycine or taurine a cholic chenodeoxycholic backbone the liver by enzyme acid-CoA:amino N-acyltransferase (BAAT). Here, we describe microbial, chemical, physiological consequences of BAAT gene deletion mice. -/- mice were underweight after weaning but quickly exhibited catch-up growth....
To characterize the growth factors contained in equine amniotic membrane allograft (eAM; StemWrap scaffold and StemWrap+ injection) to evaluate effect of eAM on distal limb wound healing.Prospective experimental controlled study.Eight adult horses.Transforming factor (TGF)-β1, vascular endothelial (VEGF), epidermal factor, platelet-derived factor-BB, prostaglandin E2 (PGE2 ) concentrations were assessed with enzyme-linked immunosorbent assay. Two full-thickness 6.25-cm2 skin wounds created...
Typical enteropathogenic Escherichia coli (tEPEC) is a leading cause of diarrhea and associated death in children worldwide. Atypical EPEC (aEPEC) lacks the plasmid encoding bundle-forming pili considered less virulent, but molecular mechanism virulence poorly understood. We recently identified kittens as host for aEPEC where intestinal epithelial colonization was with diarrheal disease death. The purposes this study were to (i) determine genomic similarity between kitten human isolates (ii)...