A5057831654- Veterinary Equine Medical Research
- Spine and Intervertebral Disc Pathology
- Antibiotics Pharmacokinetics and Efficacy
- Cervical and Thoracic Myelopathy
- Spinal Hematomas and Complications
- Airway Management and Intubation Techniques
- Infectious Diseases and Mycology
- Spinal Fractures and Fixation Techniques
- Microbial Inactivation Methods
- Tracheal and airway disorders
- Surgical Sutures and Adhesives
- Bacterial Identification and Susceptibility Testing
- Veterinary Orthopedics and Neurology
- Shoulder Injury and Treatment
- Clostridium difficile and Clostridium perfringens research
- Gastrointestinal disorders and treatments
- Intestinal Malrotation and Obstruction Disorders
- Veterinary Pharmacology and Anesthesia
- Reconstructive Surgery and Microvascular Techniques
- Antibiotic Resistance in Bacteria
- Gut microbiota and health
- Anesthesia and Pain Management
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- Veterinary medicine and infectious diseases
North Carolina State University
2014-2025
North Central State College
2014-2024
Heidelberg University
2017
Michigan State University
2010-2011
University of Veterinary Medicine Hannover, Foundation
2005
Summary Background Tumours of the oral cavity in horses are rare, and because they not easily visible, their diagnosis is often delayed. Different types equine tongue tumours have been described, but information about clinical signs, treatments outcomes very limited. Objectives To identify with a confirmed antemortem tumour to document presentation, treatment outcome. Study design Retrospective multicentre study. Methods Medical records (1997–2024) from eight specialty or referral practices...
Reasons for performing study: Despite modern medical diagnostic imaging, it is not possible to identify reliably the exact location of spinal cord compression in horses with cervical vertebral stenotic myelopathy (CVSM). Vertebral canal endoscopy has been successfully used man and a technique (CVCE) described equine cadavers. Objective: To determine feasibility safety CVCE healthy mature horses. Methods: Six were anaesthetised. A flexible videoendoscope was subsequently introduced via...
Antimicrobial drug concentrations in the gastrointestinal tract likely drive antimicrobial resistance enteric bacteria. Our objective was to determine concentration of ceftiofur and its metabolites steers treated with crystalline-free acid (CCFA) or hydrochloride (CHCL), effect these drugs on minimum inhibitory (MIC) fecal Escherichia coli, evaluate shifts microbiome. Steers were administered either a single dose (6.6 mg/kg) CCFA 2.2 mg/kg CHCL every 24 hours for 3 days. Ceftiofur measured...
Objectives: To determine (1) the short- (to hospital discharge) and long- (>6 months) term survival, (2) factors associated with short-term (3) perioperative course for horses resection anastomosis of descending colon. Study Design: Multicentered case series. Animals: Horses (n=43) that had colon anastomosis. Methods: Medical records (January 1995–June 2009) 7 equine referral hospitals were reviewed recovered from anesthesia. Retrieved data included history, results clinical...
Introduction Integrated time nanosecond pulse irreversible electroporation (INSPIRE) is a novel tumor ablation modality that employs high voltage, alternating polarity waveforms to induce cell death in well-defined volume while sparing the underlying tissue. This study aimed demonstrate vivo efficacy of INSPIRE against spontaneous melanoma standing, awake horses. Methods A custom applicator and generation system were utilized pilot treat horses presenting with melanoma. treatments...
Summary A 3‐year‐old Thoroughbred gelding presented with a history of neurological signs, including incoordination in his hindlimbs, about 7 months' duration. On initial examination, the horse exhibited ataxia and paresis all limbs more severe deficits hindlimbs. Cervical radiographs displayed osteoarthritis articular processes between C5 C6. subsequent cervical myelography dorsal contrast column was reduced by 90% at level intervertebral space vertebral canal endoscopy, epidural...
OBJECTIVE To evaluate quality of recovery from general anesthesia in horses after induction with propofol and ketamine versus midazolam ketamine. DESIGN Prospective randomized crossover study. ANIMALS 6 healthy adult horses. PROCEDURES Horses were premedicated xylazine (1.0 mg/kg [0.45 mg/lb], IV), was induced (0.1 [0.045 IV) or (0.5 [0.23 followed by (3.0 [1.36 IV). endotracheally intubated, maintained isoflurane. After 60 minutes, given romifidine (0.02 [0.009 allowed to recover...
Localisation of spinal cord compression in horses with cervical vertebral stenotic myelopathy is inexact. Vertebral canal endoscopy has been used man to localise lesions and the potential become a useful diagnostic technique horses.To establish surgical approach via atlanto-occipital space equine cadavers describe endoscopic anatomy epidural subarachnoid spaces.The 25 mature were assess 3 methods canal, including 2 minimally invasive one open technique. Once had made, flexible videoendoscope...
Objective: The intestinal concentrations of antimicrobial drugs that select for resistance in fecal bacteria cattle are poorly understood. Our objective was to associate active drug the intestine steers with changes profile and composition microbiome. Methods: Steers were administered either a single dose (12.5 mg/kg) or 3 multiple doses (5 enrofloxacin subcutaneously every 24 h. Enrofloxacin ciprofloxacin fluid measured over 96 h, abundance MIC E. coli culture microbiota by 16S rRNA gene...
To study the safety and efficacy of algorithmically controlled electroporation (ACE) against spontaneous equine melanoma.
The objectives of this study were to examine the pharmacokinetics tobramycin in horse following intravenous (IV), intramuscular (IM), and intra‐articular (IA) administration. Six mares received 4 mg/kg IV, IM, IV with concurrent IA administration (IV+IA) a randomized 3‐way crossover design. A washout period at least 7 days was allotted between experiments. After administration, volume distribution, clearance, half‐life 0.18 ± 0.04 L/kg, 1.18 0.32 mL·kg/min, 4.61 1.10 h, respectively....
The conventional arthroscopic approach to the palmar/plantar aspect of distal interphalangeal joint (DIPJ) may result in inadvertent penetration digital flexor tendon sheath (DFTS) and navicular bursa (NB). This iatrogenic communication would be undesirable subsequent lavage a septic DIPJ.A lateral/medial DIPJ will significantly lower rate DFTS NB, whilst still providing adequate intra-articular evaluation.The or novel was performed on cadaver fore- hindlimbs (30 limbs/approach)....
To characterize the growth factors contained in equine amniotic membrane allograft (eAM; StemWrap scaffold and StemWrap+ injection) to evaluate effect of eAM on distal limb wound healing.Prospective experimental controlled study.Eight adult horses.Transforming factor (TGF)-β1, vascular endothelial (VEGF), epidermal factor, platelet-derived factor-BB, prostaglandin E2 (PGE2 ) concentrations were assessed with enzyme-linked immunosorbent assay. Two full-thickness 6.25-cm2 skin wounds created...
Summary Reasons for performing study Back pain is a common cause of gait alterations and poor performance in horses, but the available imaging modalities are frequently insufficient to isolate underlying pathology. In human patients, epidural endoscopy (epiduroscopy) successfully used diagnose treat challenging cases lower back pain. Endoscopy cervical space has previously been reported anaesthetised horses. Objectives To develop technique lumbosacral epiduroscopy standing horses describe...
Abstract Fluoroquinolones are a class of antimicrobial commonly used in human medicine, and deemed critical by the World Health Organization. Nonetheless, two formulations approved for treatment respiratory disease beef cattle. The objective this study was to determine gastrointestinal pharmacokinetics impact on enteric bacteria cattle when receiving one dosing regimens (high: 40 mg/kg SC once or low: 20 IM q48hr) danofloxacin, utilized synthetic fluoroquinolone veterinary medicine....
Navigational ultrasound imaging, also known as fusion is a novel technology that allows real-time imaging to be correlated with previously acquired computed tomography (CT) or magnetic resonance (MRI) study. It has been used in man aid interventional therapies and shown valuable for sampling assessing lesions diagnosed MRI CT are equivocal on ultrasonography. To date, there no reports of the use this modality veterinary medicine.To assess whether navigational can assist commonly performed...
Abstract Objective To determine the ability of a commercial cryotherapy system (Game Ready Equine) to cool metacarpal subcutaneous tissue and superficial digital flexor tendon (SDFT) in horses. Study design Experimental study. Animals or sample population Six healthy adult Methods Thermocouples were implanted into tissues SDFT six Two treatments (cryotherapy with 5–50 mmHg intermittent compression) randomly assigned forelimbs performed for 20 minutes. Temperatures compared target range...