A5100440311- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Trauma and Emergency Care Studies
- Traffic and Road Safety
- Congenital Diaphragmatic Hernia Studies
- Urban Transport and Accessibility
- Assisted Reproductive Technology and Twin Pregnancy
- Birth, Development, and Health
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Injury Epidemiology and Prevention
- Retinal Diseases and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Geoscience and Mining Technology
- Glaucoma and retinal disorders
- Neonatal and fetal brain pathology
- Healthcare Policy and Management
- HIV/AIDS Research and Interventions
- Emergency and Acute Care Studies
- Neuroscience of respiration and sleep
- HIV, Drug Use, Sexual Risk
- Respiratory viral infections research
- Ophthalmology and Visual Impairment Studies
- Preterm Birth and Chorioamnionitis
- Child Nutrition and Water Access
Beijing Tongren Hospital
2015-2025
Capital Medical University
2015-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2001-2025
Huazhong University of Science and Technology
2019-2025
Peking Union Medical College Hospital
2016-2025
Affiliated Hospital of Southwest Medical University
2025
Xiamen University
2025
Tianjin Medical University General Hospital
2025
Jiangsu University
2014-2024
RTI International
2012-2024
Between-hospital variation in outcomes among extremely preterm infants is largely unexplained and may reflect differences hospital practices regarding the initiation of active lifesaving treatment as compared with comfort care after birth. We studied born between April 2006 March 2011 at 24 hospitals included Eunice Kennedy Shriver National Institute Child Health Human Development Neonatal Research Network. Data were collected for 4987 before 27 weeks gestation without congenital anomalies....
Bronchopulmonary dysplasia is a prevalent complication after extremely preterm birth. Inflammation with mechanical ventilation may contribute to its development. Whether hydrocortisone treatment the second postnatal week can improve survival without bronchopulmonary and adverse neurodevelopmental effects unknown. We conducted trial involving infants who had gestational age of less than 30 weeks been intubated for at least 7 days 14 28 days. Infants were randomly assigned receive either (4 mg...
To investigate the relationships among blood pressure (BP) values, antihypotensive therapies, and in-hospital outcomes to identify a BP threshold below which therapies may be beneficial. Prospective observational study of infants 23(0/7) 26(6/7) weeks' gestational age. Hourly values therapy use in first 24 hours were recorded. Low was investigated by using 15 definitions. Outcomes examined regression analysis controlling for age, number low illness severity. Of 367 enrolled, 203 (55%)...
The Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network (NRN) extremely preterm birth outcome model is widely used for prognostication by practitioners caring families expecting birth. provides information on mean outcomes from 1998 to 2003 does not account substantial variation in among US hospitals.To update validate the NRN most infants United States.This prognostic study included 3 observational cohorts January 1, 2006, December 31,...
Programmed necrosis (necroptosis) plays an important role in development, tissue homeostasis, and disease pathogenesis. The molecular mechanisms that regulate necroptosis the heart its physiological relevance myocardial remodeling failure remain largely unknown.Here, we identified obligate function for TAK1 (transforming growth factor β-activated kinase 1, gene name Map3k7) regulating necroptotic myocyte death, remodeling, propensity. Cardiac-specific ablation of Map3k7 mice induced...
<h3>Objective</h3> To investigate the relationships between early blood pressure (BP) changes, receipt of antihypotensive therapy and 18–22 months' corrected age (CA) outcomes for extremely preterm infants. <h3>Design</h3> Prospective observational study infants 23<sup>0/7</sup>–26<sup>6/7</sup> weeks' gestational (GA). Hourly BP values exposure in first 24 h were recorded. Four groups defined: who did or not receive whom rise at expected rate (defined as an increase mean arterial ≥5 mm...
Background: Treatment resistance is a significant problem among young people experiencing moderate-to-severe anxiety, affecting nearly half of all patients. This study investigated the safety and efficacy cannabidiol (CBD), non-intoxicating component Cannabis sativa, for anxiety disorders in who previously failed to respond standard treatment. Methods: In this open-label trial, 31 aged 12–25 years with DSM-5 disorder no clinical improvement despite treatment cognitive-behavioral therapy...
We sought to determine if a center's approach care of premature infants at the youngest gestational ages (22-24 weeks' gestation) is associated with clinical outcomes among older (25-27 gestation). Inborn 401 1000 g birth weight and 22 0/7 27 6/7 gestation from 2002 2008 were enrolled into prospectively collected database 20 centers participating in Eunice Kennedy Shriver National Institute Child Health Human Development Neonatal Research Network. Markers an aggressive for 22- 24-week...
Objective This study aimed to evaluate the association between six complete blood count (CBC)-derived inflammatory markers [neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte (MLR), platelet-to-lymphocyte (PLR), systemic immune-inflammatory index (SII), response (SIRI), and pan-immune inflammation value (PIV)] risk of frailty mortality. Methods Data were obtained from National Health Nutrition Examination Survey (NHANES) 1999–2018. Mortality was identified using Death Index until...
To examine factors affecting center differences in mortality for extremely low birth weight (ELBW) infants. We analyzed data 5418 ELBW infants born at 16 Neonatal Research Network centers during 2006-2009. The primary outcomes of early (≤12 hours after birth) and in-hospital were assessed by using multilevel hierarchical models. Models developed to investigate associations rates selected interventions with while adjusting patient-level risk factors. These analyses performed all gestational...
Abstract Background The relationships between air pollutants and mental behavioral disorders (MBDs) remain unclear. We aimed to identify the primary affecting health evaluate short-term effects on emergency ambulance dispatches (EADs) due MBDs. Methods Time-stratified case-crossover study conditional logistic regression model were adopted explore impact of EADs MBDs from 2013 2020 in Shenzhen, China. In order clarify influence gender age association, subgroup analysis was carried out. also...
Background: Patients with cancer often develop a prothrombotic state that can evolve into venous and arterial thrombosis, which is associated poor clinical outcomes. Glioblastoma multiforme (GBM) the most frequently but underlying causes of this are poorly defined. Objectives: We designed study to characterize expression coagulation factor X (FX) its alternatively spliced transcripts in glioblastoma tissues surgically removed from patients clonal cell lines. Methods: The F10 mRNA FX protein...
Objective: To study the 5-year long-term efficacy and complications of adjuvant external drainage subretinal fluid therapy in patients with severe exudative retinal detachment (ERD) secondary to stage 3B juvenile Coats disease. Methods: This was a retrospective case series study. From January 2014 December 2018, twenty-three eyes 23 ERD disease diagnosed at Beijing Tongren Hospital, Capital Medical University were included this All underwent wide-field imaging, fluorescein fundus angiography...
The present study aimed to investigate the positive rate of adolescent idiopathic scoliosis (AIS) among school children in Xiamen, Fujian province, China, and evaluate its possible risk factors. was a school-based, cross-sectional screening program Xiamen city. A total 19,315 aged 9-18 years were recruited using multistage sampling approach. Scoliosis performed through visual inspection clinical signs, Adams forward bending test, measurement trunk rotation angles scoliometer. Demographic...