Jong Dae Lee

ORCID: 0000-0003-2866-9841
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About
Contact & Profiles
Research Areas
  • Vestibular and auditory disorders
  • Ear Surgery and Otitis Media
  • Meningioma and schwannoma management
  • Hearing, Cochlea, Tinnitus, Genetics
  • Neurofibromatosis and Schwannoma Cases
  • Facial Nerve Paralysis Treatment and Research
  • Ophthalmology and Eye Disorders
  • Ear and Head Tumors
  • Glaucoma and retinal disorders
  • Nasal Surgery and Airway Studies
  • Sinusitis and nasal conditions
  • Cerebral Venous Sinus Thrombosis
  • Hearing Loss and Rehabilitation
  • Tracheal and airway disorders
  • Head and Neck Surgical Oncology
  • Cardiac Imaging and Diagnostics
  • Glioma Diagnosis and Treatment
  • Orthopedic Surgery and Rehabilitation
  • Oral and Maxillofacial Pathology
  • Protease and Inhibitor Mechanisms
  • Marine Ecology and Invasive Species
  • Speech and Audio Processing
  • Soft tissue tumors and treatment
  • Neuroscience of respiration and sleep
  • Otolaryngology and Infectious Diseases

Soonchunhyang University
2016-2025

Bucheon University
2019-2024

Soonchunhyang University Hospital
2022-2024

Changwon National University
2023

Gyeongsang National University
2023

Inha University
2020

Harvard University
2016

Samsung Medical Center
2014

Sungkyunkwan University
2014

Yonsei University
2007

Various surgical methods have been tried to relieve the symptoms of nasal obstruction in patients with inferior turbinate hypertrophy. Recently, coblation that uses radiofrequency and microdebrider is being increasingly used surgery. The aim this study was compare long-term postoperative outcome between coblation- microdebrider-assisted partial turbinoplasty.We selected 60 for prospective who had hypertrophied mucosa refractory medical treatment. Thirty were treated (group 1) 30 2)....

10.1097/01.mlg.0000205140.44181.45 article EN The Laryngoscope 2006-04-28

To investigate the vestibular evoked myogenic potentials (VEMPs) resulting in benign paroxysmal positional vertigo (BPPV) patients and to verify its clinical applications BPPV.A prospective study.Tertiary referral dizziness center.Forty-one with diagnosis of BPPV 92 healthy volunteers who underwent VEMP testing.Patients were treated by canalith repositioning maneuvers according affected canal, testing was performed at after treatment.Testing control group. The number times maneuver repeated...

10.1097/mao.0b013e31818a0881 article EN Otology & Neurotology 2008-11-18

Objective To investigate the effects of Steri‐Strips patch (3M) on treatment large traumatic tympanic membrane perforations (TMP). Study Design Prospective, randomized, controlled. Setting Tertiary university hospital. Subjects and Methods A randomized prospective analysis was performed between February 2009 January 2011 for TMP larger than 50% entire membrane. The results closure rate, time, hearing gain, rate otorrhea conservative observation, paper patching, patching groups were compared....

10.1177/0194599811409836 article EN Otolaryngology 2011-05-18

Objectives Malignant external otitis (MEO) is a potentially fatal infection of the auditory canal, temporal bone, and skull base. Despite treatment with modern antibiotics, MEO can lead to base osteomyelitis. Until now, there have been few studies on prognostic factors MEO. Methods We performed retrospective study identify MEO, meta-analysis other articles investigating On basis disease progression 28 patients in our were divided into 'controlled' 'uncontrolled' groups, consisting 12 16...

10.21053/ceo.2016.00612 article EN cc-by-nc Clinical and Experimental Otorhinolaryngology 2016-09-26

We evaluated the short-term efficacy of Epley, Semont, and sham maneuvers for resolving posterior canal benign paroxysmal positional vertigo (BPPV) in a prospective multicenter randomized double-blind controlled study. Subjects were randomly divided into three groups: Epley (36 patients), Semont (32 (Epley maneuver unaffected side, 31 patients). Out 14 institutes which participated this study, 5 had previous experience but not other 9 both maneuvers. Each was repeated twice if there still or...

10.1159/000365438 article EN Audiology and Neurotology 2014-01-01

Hearing loss is the most important modifiable risk factor for cognitive impairment; however, association of hearing with anatomical and functional connectivity not fully understood. This may be elucidated by evaluating findings newer imaging technologies.

10.1001/jamaoto.2023.0824 article EN JAMA Otolaryngology–Head & Neck Surgery 2023-05-11

Persistent postural-perceptual dizziness (PPPD) is a chronic functional vestibular disorder for which the Bárány Society has established diagnostic criteria. This nationwide multicenter study aims to investigate clinical features of individuals with definite PPPD and variant who do not fully meet criteria, particular focus on visual exaggeration.

10.1002/brb3.3389 article EN cc-by Brain and Behavior 2024-01-31

Background Mutations in the neurofibromatosis type 2 (NF2) tumor-suppressor gene have been identified not only NF2-related tumors but also sporadic vestibular schwannomas (VS). This study investigated genetic and epigenetic alterations blood from 30 Korean patients with VS correlated these tumor behavior. Methodology/Principal Findings NF2 mutations were detected using PCR direct DNA sequencing three highly polymorphic microsatellite markers used to assess loss of heterozygosity (LOH)...

10.1371/journal.pone.0030418 article EN cc-by PLoS ONE 2012-01-25

Objective The authors compared the efficacy of simultaneous and subsequent intratympanic dexamethasone injections for treatment idiopathic sudden sensorineural hearing loss. Study Design Prospective randomized controlled multicenter study. Setting Three tertiary university hospitals. Subjects Methods In group, was given initially with systemic steroids. 7 days after treatment. outcomes between groups according to Siegel’s criteria frequency (0.25, 0.5, 1, 2, 3, 4, 6, 8 kHz). Results A total...

10.1177/0194599811418169 article EN Otolaryngology 2011-08-04

Abstract Objective : We report six cases of facial nerve schwannomas in which surgical management allowed the preservation function. Specifically, this paper reports that a stripping surgery may provide favorable functional outcomes. Study Design A retrospective review preoperative and postoperative data for patients with schwannoma had normal function or House‐Brackmann grade II palsy before surgery. Methods Stripping surgery, removed from remaining fascicle, was attempted on patients....

10.1097/mlg.0b013e31804b1a51 article EN The Laryngoscope 2007-04-26

This study aimed to investigate the therapeutic efficacy of intratympanic dexamethasone (ITD) as a salvage treatment in sudden hearing loss (SHL) patients who had no response initial systemic combination steroid therapy.From May 2007 June 2010, 415 SHL visited 3 tertiary referral centers within 7 days disease onset. They were all treated with an identical protocol, 10-day scheduled hospitalization and oral treatment. Of these, 151 totally unresponsive 2 weeks after initiation according...

10.1097/mao.0b013e318238fc43 article EN Otology & Neurotology 2011-11-16

Abstract Vestibular schwannoma (VS) is an intracranial tumor that causes significant morbidity, including hearing loss, tinnitus, dizziness, and possibly even death from brainstem compression. However, FDA-approved pharmacologic treatments for VS do not exist. Sulforaphane (SFN) a naturally occurring isothiocyanate found in cruciferous vegetables, such as broccoli, with potent chemoprotective effects several cell types. Our objective was to determine whether SFN effective against vitro vivo...

10.1038/srep36215 article EN cc-by Scientific Reports 2016-11-02

Transcanal endoscopic ear surgery (TEES) provides minimally invasive transcanal access to the middle and improves visibility during cholesteatoma resection. However, literature on outcomes following TEES alone for removal of congenital (CC) is lacking limited small series.

10.1001/jamaoto.2022.4660 article EN JAMA Otolaryngology–Head & Neck Surgery 2023-01-19

Vestibular schwannomas (VSs) grow in the region where energy from mobile phone use is absorbed. We examined associations of VSs with use. This study included 119 patients who had undergone surgical tumor removal. used two approaches this investigation. First, a case–control for association and incidence was conducted. Both cases controls were investigated questions based on INTERPHONE guidelines. Amount according to duration, daily amount, cumulative hours compared between groups. also...

10.1007/s13277-013-1081-8 article EN cc-by Tumor Biology 2013-08-26

Abstract Objectives: To evaluate the necessity of canine fossa puncture (CFP) by comparing symptom scores and postoperative computed tomography (CT) findings between patients with severe maxillary sinus disease who underwent CFP those clearance through a middle meatal antrostomy (MMA). Study Design: A prospective, randomized study. Materials Methods: Fourteen met inclusion criteria for each MMA groups. In both groups, all diseased sinuses were addressed in same manner using surgical...

10.1097/mlg.0b013e318169028d article EN The Laryngoscope 2008-05-28

Intratympanic steroids are being increasingly used in the treatment of sudden sensorineural hearing loss (SSNHL) after failure systemic therapy. This study evaluated efficacy administering intratympanic dexamethasone (ITD) as a salvage for severe to profound SSNHL.We reviewed medical records patients who presented with SSNHL between January 2007 and December 2009. ITD was given about 14 days initial treatment. Successful recovery defined complete or partial using Sigel's criteria. We...

10.3342/ceo.2010.3.3.122 article EN cc-by-nc Clinical and Experimental Otorhinolaryngology 2010-01-01

Objectives The traditional canal wall down mastoidectomy (CWDM) procedure commonly has potential problems of altering the anatomy and physiology middle ear mastoid. This study evaluated outcomes in patients who underwent modified (mCWDM) mastoid obliteration using autologous materials. Methods Our included 76 with chronic otitis media, cholesteatoma, adhesive mCWDM materials between 2010 2015. Postoperative hearing airbone gap complications were evaluated. Results During average follow-up 64...

10.21053/ceo.2018.01333 article EN cc-by-nc Clinical and Experimental Otorhinolaryngology 2019-01-31

Inlay butterfly cartilage tympanoplasty makes the graft easy, and reduces operating time. The present study aimed to investigate outcomes of microscopic versus endoscopic inlay tympanoplasty.In this retrospective study, 63 patients who underwent with small medium chronic tympanic membrane perforation were evaluated. Twenty-four conventional 39 tympanoplasty. analyzed in terms hearing gain success rate.The surgical rate was 95.8% 92.3% those In both groups patients, postoperative air-bone gap...

10.7874/jao.2018.00549 article EN Journal of Audiology & Otology 2019-06-24

Hearing loss, which is genetically heterogeneous, can be caused by mutations in the mitochondrial DNA (mtDNA). The A1555G mutation of 12S ribosomal RNA (rRNA) gene mtDNA has been associated with both aminoglycoside-induced and non-syndromic hearing loss many ethnic populations. Here, we report for first time clinical genetic characterization nine Korean pedigrees loss. These families carry rRNA exhibit variable penetrance expressivity Specifically, these ranged between 28.6% 75%, an average...

10.1371/journal.pone.0042463 article EN cc-by PLoS ONE 2012-08-06
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