A5051720991- Mosquito-borne diseases and control
- Malaria Research and Control
- Blood donation and transfusion practices
- Hemoglobinopathies and Related Disorders
- Viral Infections and Vectors
- Parasites and Host Interactions
- Parasitic Diseases Research and Treatment
- Digital Imaging for Blood Diseases
- Liver Disease Diagnosis and Treatment
- Research on Leishmaniasis Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- AI in cancer detection
- Complement system in diseases
- Dermatological diseases and infestations
- Sepsis Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Pancreatitis Pathology and Treatment
- Parasite Biology and Host Interactions
Mahidol Oxford Tropical Medicine Research Unit
2007-2023
Mahidol University
2007-2023
Artemisinin-based combination therapy (ACT) is currently promoted as a strategy for treating both uncomplicated and severe falciparum malaria, targeting asexual blood-stage Plasmodium parasites. However, the effect of ACT on sexual-stage parasites remains controversial. To determine clearance P. from 342 uncomplicated, 217 severe, adult malaria cases, we reviewed followed peripheral blood 4 wk after starting ACT. All patients presented with sexual stage admission, were treated...
People can become infected with cutaneous larva migrans (CLM) through skin penetration by the infective zoonotic larvae of hookworms. Few studies have investigated CLM's immunodiagnosis, and existing were limited to crude somatic or excretory/secretory antigens (Ags) from adult worms. Here, we aimed develop an indirect enzyme-linked immunosorbent assay (ELISA) differentiate diagnose hwCLM detecting immunoglobulin (Ig)E, IgG, IgG subclasses 1-4 (IgG1-4) against Ag Ancylostoma caninum...
In acute uncomplicated falciparum malaria, there is a continuum from mild to severe malaria. However, no mathematical system available predict malaria patients turning This study aimed devise simple and reliable model of Malaria Severity Prognostic Score (MSPS). The was performed in adult with admitted the Bangkok Hospital for Tropical Diseases between 2000 2005. Total 38 initial clinical parameters were identified usual recovery or deterioration stepwise multiple discriminant analysis get...
The implementation of a laboratory information system (LIS) at the Hospital for Tropical Diseases in Thailand provides valuable medical resources, particularly dengue. Hematocrit (Hct), which is often derived from hemoglobin (Hgb), important diagnosis and management This study aimed to evaluate Hct value obtained LIS automated analyzer. We prospectively enrolled 163 hospitalized adults with dengue, whom 1,141 real-time complete blood count (CBC) results were via hematology analyzer updated...
Dengue virus infection most commonly has mild-to-moderate nonspecific clinical presentations that overlap with other diseases. Dengue-specific tests are used for those patients acute febrile illness in dengue-endemic areas. There is one study vitro showed a false-positive dengue-immunoglobulin M (dengue IgM) test blood from patient systemic lupus erythematosus (SLE). Here, we demonstrated dengue IgM SLE. The had fever, cytopenia, and skin rash, but her variables more closely matched the...
Abstract Severe dengue infection is associated with life-threatening complications, including severe bleeding. The bleeding tendency typically the shock phase of infection, for which blood replacement may be needed. However, repetitive transfusion can lead to volume overload. Administration recombinant activated factor VII (rFVIIa) might used counteract without inducing We describe case a patient who presented intractable bleeding; he was initially treated massive transfusions, resulted in...
Abstract Severe dengue infection is associated with life-threatening complications, including severe bleeding. The bleeding tendency typically the shock phase of infection, for which blood replacement may be needed. However, repetitive transfusion can lead to volume overload. Administration recombinant activated factor VII (rFVIIa) might used counteract without inducing We describe case a patient who presented intractable bleeding; he was initially treated massive transfusions, resulted in...