A5035960655- Acute Myeloid Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Mosquito-borne diseases and control
- Retinoids in leukemia and cellular processes
- Hemoglobinopathies and Related Disorders
- Eosinophilic Disorders and Syndromes
- Chronic Lymphocytic Leukemia Research
- Advanced biosensing and bioanalysis techniques
- SARS-CoV-2 detection and testing
- Blood donation and transfusion practices
- Multiple Myeloma Research and Treatments
- Acute Lymphoblastic Leukemia research
- Iron Metabolism and Disorders
- HIV Research and Treatment
- Tuberous Sclerosis Complex Research
- Glioma Diagnosis and Treatment
- Hematological disorders and diagnostics
- Biosensors and Analytical Detection
- Neutropenia and Cancer Infections
- Hematopoietic Stem Cell Transplantation
- Lymphoma Diagnosis and Treatment
- Heparin-Induced Thrombocytopenia and Thrombosis
- Complement system in diseases
- Viral Infections and Outbreaks Research
- Kruppel-like factors research
Rajavithi Hospital
2014-2024
Ministry of Public Health
2024
Rapid, accurate, and low-cost detection of SARS-CoV-2 is crucial to contain the transmission COVID-19. Here, we present a cost-effective smartphone-based device coupled with machine learning-driven software that evaluates fluorescence signals CRISPR diagnostic SARS-CoV-2. The consists three-dimensional (3D)-printed housing optic components allow excitation fluorescent reporters selective emission smartphone. Custom equipped binary classification model has been developed quantify acquired...
Abstract Background Bone complications are common in patients with thalassemia. Objectives To assess risk factors for osteoporosis nonmajor thalassemia and its prevalence randomly selected adult Thailand. Patients methods We included 190 (58 men 132 women) intermedia or minor this cross-sectional study. untreated hypogonadism, hypothyroidism, menopause, a history of treatment medications that have effects on skeletal bone metabolism were excluded. mass density (BMD) the femoral neck was...
"AML with MECOM rearrangement" was recently categorized by WHO classification 2022 regardless of blast count, which included those present MDS and AML into this group. We aim to explore frequency, clinical characteristics, outcomes in subtype among Thai myeloid neoplasms. data collected from a multicenter study rearrangements were analyzed compared other subtypes. A total 15 cases rearrangement detected, 5/166 (3%) while 10/1082 (0.9%) AML. Eleven (73%) female. showed lower hemoglobin, but...
Background: ITP is a disease which develops as result of increased activity the reticuloendothelial system (mainly liver and spleen). The role high-dose short- acting corticosteroids in treatment immune thrombocytopenic purpura adults controversial. We assessed effectiveness corticosteroids, compared with that standard oral prednisolone therapy, for initial purpura. Methods: 52 patients were randomized to receive pulse methylprednisolone (1gm/day) 3 days, or 1 mg/kg/day 84 days. Response was...
Dengue virus infection most commonly has mild-to-moderate nonspecific clinical presentations that overlap with other diseases. Dengue-specific tests are used for those patients acute febrile illness in dengue-endemic areas. There is one study vitro showed a false-positive dengue-immunoglobulin M (dengue IgM) test blood from patient systemic lupus erythematosus (SLE). Here, we demonstrated dengue IgM SLE. The had fever, cytopenia, and skin rash, but her variables more closely matched the...
Acute myeloid leukemia (AML) is a common, challenging hematologic malignancy worldwide. Thai data on its characteristics and outcomes have never been systematically reported, to our knowledge. The objective of this study was determine the clinical features patients with AML.This prospective observational nine academic hospitals. Patients newly diagnosed AML were invited register online.A total 679 included. presence circulating peripheral blood blasts correlated high white cell count....
Surveillance testing is a key strategy to control the spread of COVID-19. Unlike gold standard method, quantitative reverse transcription polymerase chain reaction (RT-qPCR), CRISPR diagnostics have recently become more appealing alternative as they are proven be faster, simpler, and affordable. However, current diagnostic readouts typically non-quantitative, making them error-prone lacking crucial information viral load. To further improve we developed custom computer vision algorithm that...
Background: Polycythemia vera has been found in a wide range of hematopoietic tissue disorders, but rarely concomitant with renal abnormality. To our knowledge there is only one available report patient polycythemia angiomyolipoma, and the does not cover clinical course this rare finding. Objectives: presentation right angiomyolipoma. Methods: We retrospectively reviewed medical records who presented Results: Our mass diagnosed by point mutation gene for Janus kinase 2. The was as...
Abstract Severe dengue infection is associated with life-threatening complications, including severe bleeding. The bleeding tendency typically the shock phase of infection, for which blood replacement may be needed. However, repetitive transfusion can lead to volume overload. Administration recombinant activated factor VII (rFVIIa) might used counteract without inducing We describe case a patient who presented intractable bleeding; he was initially treated massive transfusions, resulted in...
Abstract Background A Janus kinase 2 (JAK2) mutation polycythemia vera (PV) is a common manifestation of stem cell disorder. However, available data on the clinical and treatment response JAK2-negative PV patients are limited. Objectives We report case course patient with left hemiparesis who was JAK2V617-negative. Methods conducted literature review compared our previously published reports P V. Results Our presented without previous history hematological disease. He diagnosed based British...
Abstract Background: Primary granulocytic sarcoma (GS) only rarely presents with an ovarian mass classified as extramedullary myeloid progenitor tumor cells. Few patients cases of primary GS survive after systemic chemotherapy. Objective: To present a case treated complete course The patient is currently in remission. Methods: Retrospective review medical records and comparison previous reports. Results: A 41-year-old woman presented 6 months duration. There was no history hematologic...
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid (AML) with unique clinical presentation and prognosis. This study aimed to investigate the epidemiology, characteristics, treatments, outcomes Thai APL patients dominantly treated all-trans-retinoic acid (ATRA) combined chemotherapy-based therapy.This was an eight-year prospective, observational from nine academic hospitals in Leukemia Working Group (TALWG) Society Hematology, which included newly diagnosed patients,...
Abstract Severe dengue infection is associated with life-threatening complications, including severe bleeding. The bleeding tendency typically the shock phase of infection, for which blood replacement may be needed. However, repetitive transfusion can lead to volume overload. Administration recombinant activated factor VII (rFVIIa) might used counteract without inducing We describe case a patient who presented intractable bleeding; he was initially treated massive transfusions, resulted in...