A5073682047- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Neutropenia and Cancer Infections
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Hematological disorders and diagnostics
- Hematopoietic Stem Cell Transplantation
- Chronic Lymphocytic Leukemia Research
- Chronic Myeloid Leukemia Treatments
- CAR-T cell therapy research
- Peripheral Neuropathies and Disorders
- Cancer Genomics and Diagnostics
- Antifungal resistance and susceptibility
- Retinoids in leukemia and cellular processes
- Heparin-Induced Thrombocytopenia and Thrombosis
- SARS-CoV-2 and COVID-19 Research
- Adrenal and Paraganglionic Tumors
- Viral-associated cancers and disorders
- Mosquito-borne diseases and control
- Fungal Infections and Studies
- CNS Lymphoma Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Vitamin D Research Studies
- vaccines and immunoinformatics approaches
Thammasat University
2015-2024
Pathumthani University
2023
University of British Columbia
2018-2020
Vancouver General Hospital
2017-2019
Leukemia & Lymphoma Society of Canada
2018
BC Cancer Agency
2018
Siriraj Hospital
2013
Mahidol University
2013
We sought to refine the clinical picture of primary adrenal lymphoma (PAL), a rare lymphoid malignancy with predominant manifestation and risk insufficiency.
Abstract Background MYC/BCL2 double expression (DE) is associated with poor prognosis in patients diffuse large B-cell lymphoma (DLBCL) receiving rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP). This study aimed to determine whether the addition of DE National Comprehensive Cancer Network Internal Prognostic Index (NCCN-IPI) could improve prediction disease progression DLBCL treated R-CHOP. Methods confirmatory prognostic factor retrospectively recruited...
Objective: The previously reported kappa/lambda ratio cut-offs for plasma cell clonality by immunohistochemistry were in different values. This study aimed to identify the with highest accuracy diagnosis of multiple myeloma.Methods: Bone marrow specimens consecutively recruited between January 2011 and March 2019. patients at least 18 years old clinical suspicion myeloma had bone ≥10% CD138 immunohistochemistry. index test was immunohistochemical stains ratio. reference standard classify as...
The antibiotic stewardship program (ASP) is a necessary part of febrile neutropenia (FN) treatment. Pharmacist-driven ASP one the meaningful approaches to improve appropriateness usage. Our study aimed determine role pharmacist in ASPs for FN patients. We prospectively studied at Thammasat University Hospital between August 2019 and April 2020. primary outcome was compare appropriate use target antibiotics pharmacist-driven group control group. results showed 90 events 66 choice an...
ABSTRACT. Early detection of dengue virus infection will lead to proper management and reduction in morbidity/mortality. Monocyte distribution width (MDW) was recently approved for use the early sepsis. Because monocytes are involved innate immune system against viral infection, we sought determine changes MDW develop validate a new predictive score infection. This study included patients who presented with symptoms or signs related had complete blood count investigation performed during...
A 6-year retrospective cohort study was conducted among Thai hematologic malignancy (HM) patients receiving intensive chemotherapy. Of the 145 eligible 893 chemotherapy sessions, 46.9% were female, median age 52 years, and most common HM diagnosis diffuse large B-cell lymphoma (46.2%). Febrile neutropenia (FN) occurred in 14.9% of sessions with an incidence 24.8 per 1,000 cycles year. Independent factors associated FN first cycle [adjusted hazard ratio (aHR) 4.1], having hemoglobin ≤100 g/L...
Background Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive lymphoma. The standard first-line therapy for DLBCL consists of rituximab cyclophosphamide doxorubicin vincristine and prednisone (R-CHOP). About 50–70% patients may be cured by R-CHOP. There was no data on external validation comparison international prognostic index, revised-IPI (R-IPI), enhanced-IPI (NCCN-IPI) to predict treatment outcomes in middle-income country with a resourced-limited setting.Objectives We...
Background: High dose chemotherapy and autologous stem cell transplant (ASCT) is the preferred consolidation strategy in treatment of eligible patients with multiple myeloma related plasma dyscrasias. Given high volume patients, longer wait times cost health care, out-patient transplants for standard care at Vancouver General Hospital. We present our experience from last 10 years. Methods: In British Columbia, Leukemia/Bone Marrow Transplant Program BC sole program serving province. The...
Aim: To determine role of pharmacists in an antibiotic stewardship program (ASP) for febrile neutropenic patients. Methods: A prospective study four medical wards at Thammasat University Hospital between August 2019 and April 2020. Two were designated as the pharmacist-driven ASP group two other a control group. Our primary outcome was to compare appropriate use target antibiotics Results: The results showed 90 events 66 Choice significantly higher than (88.9% versus 51.1%, p<0.001)....
"AML with MECOM rearrangement" was recently categorized by WHO classification 2022 regardless of blast count, which included those present MDS and AML into this group. We aim to explore frequency, clinical characteristics, outcomes in subtype among Thai myeloid neoplasms. data collected from a multicenter study rearrangements were analyzed compared other subtypes. A total 15 cases rearrangement detected, 5/166 (3%) while 10/1082 (0.9%) AML. Eleven (73%) female. showed lower hemoglobin, but...
Introduction: Antithymocyte globulin (ATG) has been demonstrated to reduce the incidence of graft-versus-host disease (GVHD); however, it remains controversial whether these gains are offset by an increase in relapse. Methods: We conducted a retrospective historical control study consisting patients (n = 210) who underwent myeloablative allogeneic hematopoietic stem-cell transplantation (HSCT) from 2014 2020. Results: The acute GVHD was lower ATG group (51.4%) than non-ATG (control) (70.0%,...
Universal antifungal treatment has been recommended among hematology patients during chemotherapy to prevent invasive aspergillosis (IA) in developed countries, but it remains a significant challenge resource-limited settings. Identifying at-risk individuals could enhance clinical outcomes. A prospective pilot study was conducted at four Thai tertiary care hospitals from April 2021 January 2023, aiming assess the correlation and potential of nasal wash galactomannan (GM) as an IA predictor...
A 76-year-old woman developed progressive painful peripheral neuropathy and blue discolouration of the sclerae over one year. Physical examination revealed bilateral (image) skin hyperpigmentation face extremities, but no lymphadenopathy or hepatosplenomegaly. Laboratory investigations identified a monoclonal immunoglobulin G kappa paraprotein elevated vascular endothelial growth factor. There was evidence endocrine dysfunction. Bone marrow biopsy showed involvement by clonal kappa-positive...
Acute myeloid leukemia (AML) is a common, challenging hematologic malignancy worldwide. Thai data on its characteristics and outcomes have never been systematically reported, to our knowledge. The objective of this study was determine the clinical features patients with AML.This prospective observational nine academic hospitals. Patients newly diagnosed AML were invited register online.A total 679 included. presence circulating peripheral blood blasts correlated high white cell count....