A5026568196- Hematopoietic Stem Cell Transplantation
- Acute Myeloid Leukemia Research
- Hemoglobinopathies and Related Disorders
- Acute Lymphoblastic Leukemia research
- Chronic Myeloid Leukemia Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Immune Cell Function and Interaction
- Polyomavirus and related diseases
- Venous Thromboembolism Diagnosis and Management
- Hematological disorders and diagnostics
- Lymphoma Diagnosis and Treatment
- Iron Metabolism and Disorders
- Blood groups and transfusion
- Multiple Myeloma Research and Treatments
- Chemotherapy-induced cardiotoxicity and mitigation
- Amyloidosis: Diagnosis, Treatment, Outcomes
- CAR-T cell therapy research
- Blood Coagulation and Thrombosis Mechanisms
- Metalloenzymes and iron-sulfur proteins
- Phagocytosis and Immune Regulation
- Histone Deacetylase Inhibitors Research
- Multiple Sclerosis Research Studies
- Mesenchymal stem cell research
- Glioma Diagnosis and Treatment
- Kruppel-like factors research
Thammasat University
2018-2024
The University of Texas MD Anderson Cancer Center
2022-2024
Thammasat University Hospital
2023-2024
Analysis of outcomes patients enrolled in the World Bleeding Disorders Registry (WBDR). 87 Hemophilia Treatment Centers around world participating WBDR. Data on 10,276 people with hemophilia demonstrate wide discrepancies care globally. Care provided low-income countries lags behind high-income by up to 40 years.
The introduction of posttransplant cyclophosphamide (PTCy)-based graft-versus-host disease (GVHD) prophylaxis lead to significant improvements in haploidentical stem cell transplantation (haplo-SCT) outcomes over the past decade. We retrospectively assessed long-term patients who had their first haplo-SCT between February 2009 and March 2019. Long-term survivors were defined as alive disease-free at 2 years after transplant. Three hundred thirty-five with a median age 48 (range, 18-72)...
Thalassemia is a common genetic disease in Southeast Asia. Red blood cell (RBC) transfusion an essential treatment for severe forms of thalassemia. We performed study to demonstrate RBC alloimmunization and other transfusion-related complications patients with transfusion-dependent thalassemia (TDT).A multi-center web-based registry TDT was conducted eight medical centers across Thailand. information, therapy, were collected. Factors associated each complication demonstrated using the...
With the continuous increase in use of haploidentical donors for transplantation, selection becomes increasingly important. Haploidentical have been selected primarily based on clinical characteristics, while effects killer cell immunoglobulin-like receptors (KIRs) outcomes haploidentical-hematopoietic stem transplantation (haplo-HSCT) with post-transplant cyclophosphamide (PTCy) remain inconclusive. The present study aimed to thoroughly evaluate effect KIRs and binding ligands assessed by...
Abstract Background MYC/BCL2 double expression (DE) is associated with poor prognosis in patients diffuse large B-cell lymphoma (DLBCL) receiving rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP). This study aimed to determine whether the addition of DE National Comprehensive Cancer Network Internal Prognostic Index (NCCN-IPI) could improve prediction disease progression DLBCL treated R-CHOP. Methods confirmatory prognostic factor retrospectively recruited...
Background Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive lymphoma. The standard first-line therapy for DLBCL consists of rituximab cyclophosphamide doxorubicin vincristine and prednisone (R-CHOP). About 50–70% patients may be cured by R-CHOP. There was no data on external validation comparison international prognostic index, revised-IPI (R-IPI), enhanced-IPI (NCCN-IPI) to predict treatment outcomes in middle-income country with a resourced-limited setting.Objectives We...
"AML with MECOM rearrangement" was recently categorized by WHO classification 2022 regardless of blast count, which included those present MDS and AML into this group. We aim to explore frequency, clinical characteristics, outcomes in subtype among Thai myeloid neoplasms. data collected from a multicenter study rearrangements were analyzed compared other subtypes. A total 15 cases rearrangement detected, 5/166 (3%) while 10/1082 (0.9%) AML. Eleven (73%) female. showed lower hemoglobin, but...
Clinical manifestations of patients with Hemoglobin E/beta-thalassemia vary from mild to severe phenotypes despite exhibiting the same genotype. Studies have partially identified genetic modifiers. We aimed study association between rare variants in protein-coding regions and clinical severity Thai patients.From April November 2018, a case-control was conducted based on information DNA samples collected hemoglobin over age four years. Cases were symptoms, while symptoms acted as controls....
Abstract Introduction Management of transfusion‐dependent thalassemia (TDT) can be challenging due to numerous potential disease‐related complications and comorbidities in particular age groups. The objective this study was report thalassemia‐related risk factors pediatric, adolescent, young adult patients with TDT. Methods A multicenter web‐based registry conducted TDT aged 25 years younger from eight university hospitals covering all parts Thailand. Factors significantly associated each...
A 68-year-old woman was admitted to the hospital for elective total knee arthroplasty in both knees without preceding heparin exposure. She developed adrenal haemorrhage and thrombocytopaenia on postoperative day 12, followed by right leg arterial occlusion multiple venous intra-abdominal sites thrombosis. After given unfractionated treat occlusion, platelet count gradually declined. Spontaneous heparin-induced diagnosed activation test with light transmission aggregometry. The patient...
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid (AML) with unique clinical presentation and prognosis. This study aimed to investigate the epidemiology, characteristics, treatments, outcomes Thai APL patients dominantly treated all-trans-retinoic acid (ATRA) combined chemotherapy-based therapy.This was an eight-year prospective, observational from nine academic hospitals in Leukemia Working Group (TALWG) Society Hematology, which included newly diagnosed patients,...
Phosphine is attracting interest due to the role it plays in extraterrestrial and interplanetary atmospheric environments. Phosphorus hydride anion neutral van der Waals complexes with CH4, C2H4, HCCH, CO2, H2S NH3 have been investigated as potential targets for photoelectron spectroscopy using a combination of DSD-PBEP86-D3BJ optimised geometries, W2w energies Franck–Condon simulations. All exhibit hydrogen-bonding interactions while CH4 are weakly bound, showing minimal perturbation upon...