A5078466400- Hemoglobinopathies and Related Disorders
- Hemophilia Treatment and Research
- Iron Metabolism and Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Blood groups and transfusion
- Intramuscular injections and effects
- Erythrocyte Function and Pathophysiology
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cerebral Venous Sinus Thrombosis
- Neonatal Health and Biochemistry
- Blood Coagulation and Thrombosis Mechanisms
- Diabetes Treatment and Management
- Platelet Disorders and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Blood donation and transfusion practices
- Folate and B Vitamins Research
- Pregnancy and preeclampsia studies
Aminu Kano Teaching Hospital
2021-2025
Bayero University Kano
2019-2024
This is a revision of the online November 2021 Brighton thrombosis with thrombocytopenia syndrome (TTS) case definition and new Collaboration for vaccine-induced immune (VITT). These definitions are intended use in clinical trials post-licensure pharmacovigilance activities to facilitate safety data comparability across multiple settings. They not guide management. The were developed by group subject matter process experts as part Coalition Epidemic Preparedness Innovations (CEPI)-funded...
Analysis of outcomes patients enrolled in the World Bleeding Disorders Registry (WBDR). 87 Hemophilia Treatment Centers around world participating WBDR. Data on 10,276 people with hemophilia demonstrate wide discrepancies care globally. Care provided low-income countries lags behind high-income by up to 40 years.
Objectives: This study aims to evaluate self-reported/parent-reported adherence on-demand therapy among persons with hemophilia. Material and Methods: A cross-sectional survey of 55 participants receiving recruited during outpatient appointments in 5 hemophilia treatment centers (HTCs) across Nigeria using the validated Hemophilia Regimen Treatment Adherence Scale-on-demand (Validated Scale - PRN; VERITAS-PRN) 24 questions on six (four-item) subscales (treat, time, dose, plan, remember,...
In Nigeria, low-dose prophylaxis is the standard of care as it reduces bleeding, development target joints, arthropathy, and improvement quality life. Non-adherence or poor adherence can prevent achievement these outcomes. The levels determinants (non-)adherence among persons with haaemophilia (PWH) in Sub-Saharan Africa have not been evidenced. We aimed to evaluate self-reported PWH, provide evidence determinants/predictors adherence, establish associations between nonadherence presence...
Transfusion demand in sub‐Saharan Africa is increasing. Establishment of large national blood services seems to be challenging. Hospital maintain the basic supply. However, they lack effective communication networks. Cell phones/internet provides infrastructure for establishing such networks and could help haemovigilance systems. Voluntary non‐remunerated donors are minority (<20%). It more appropriate develop strategies increase safety replacement donor instead insisting on copying...
Menstruation-induced vaso-occlusive crisis (MIVOC) is a significant cause of morbidity in women with sickle cell disease (SCD). Secretory phospholipase A2 (sPLA2) an inflammatory biomarker that elevated events such as acute chest syndrome (ACS), but its role MIVOC not previously studied. This study compared the serum level sPLA2 among and those without MIVOC. comparative cross-sectional study. 354 SCD were screened for using structured questionnaire. levels assayed standard ELISA while full...
Sickle cell disease is often complicated by retinopathy, which can be proliferative or non proliferative. Proliferative sickle retinopathy potentially leads to blindness. There a paucity of data on disease-related from Africa, where the most prevalent. We aimed determine clinical, ophthalmic, and laboratory predictors in an African population. conducted cross-sectional study 262 participants, aged 13 years above, with disease. Demographic clinical were collected using structured...
Both sickle cell anemia (SCA) and glucose-6-phosphate dehydrogenase (G6PD) deficiency are common genetically transmitted disorders associated with hemolytic anemia, a high prevalence in sub-Saharan Africa. Co-inheritance of both diseases has been reported Nigeria where the each disease is high. However, index suspicion needed to diagnose co-existence same individual. Here, we present an unusual case 32-year-old dentistry student who was known have SCA since age one year. He presented...
ABSTRACT Background In Nigeria, low-dose prophylaxis is the standard of care as it reduces bleeding, development target joints, arthropathy, and improvement quality life. Non-adherence or poor adherence can prevent achievement these outcomes. The levels determinants (non-)adherence among persons with haaemophilia (PWH) in Sub-Saharan Africa have not been evidenced. Objective To evaluate self-reported PWH, provide evidence determinants/predictors establish associations between nonadherence...