- Acute Myeloid Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hematopoietic Stem Cell Transplantation
- Neutropenia and Cancer Infections
- Hematological disorders and diagnostics
- Kruppel-like factors research
- Retinoids in leukemia and cellular processes
- Venous Thromboembolism Diagnosis and Management
- Lymphoma Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Polyomavirus and related diseases
- Mycobacterium research and diagnosis
- Antiplatelet Therapy and Cardiovascular Diseases
- Peripheral Artery Disease Management
- Venomous Animal Envenomation and Studies
- Atrial Fibrillation Management and Outcomes
- Hemoglobinopathies and Related Disorders
- Autoimmune and Inflammatory Disorders Research
- Acute Lymphoblastic Leukemia research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Colorectal and Anal Carcinomas
- Neonatal Respiratory Health Research
- Erythropoietin and Anemia Treatment
- MicroRNA in disease regulation
- Glioma Diagnosis and Treatment
Prince of Songkla University
2018-2025
Songklanagarind Hospital
2024
Creative Commons
2023
Introduction Bleeding from the affected organs is a common manifestation of amyloidosis. The risk for perioperative bleeding in patients with amyloidosis remains controversial. In this study, we aimed to compare tissue biopsies definitive diagnosis between and without amyloidosis, identify factors, generate prediction model these patients.
<title>Abstract</title> Formulas based on red blood cell indices have been used to differentiate between iron deficiency anemia (IDA) and thalassemia (Thal). However, such formulas exhibit varying efficiencies. In this study, we aimed develop a tool for discriminating IDA Thal by using the random forest (RF) gradient boosting (GB) algorithms. Complete count data from 1,143 patients with low mean corpuscular volume were collected (382 IDA, 635 Thal, 126 Thal). The randomly divided into...
Although anti-thymocyte globulin with cyclosporine (rATG/CsA), bone marrow transplantation, and eltrombopag are the cornerstone treatment for severe very aplastic anemia (SAA/vSAA), oxymetholone remains beneficial in ineligible patients.This study was conducted to compare realistic effectiveness of rATG/CsA SAA/vSAA.The primary outcome 2-year overall response rate (ORR).Factors associated ORR were evaluated using a logistic model.The secondary outcomes 3-, 6-, 12-and 18-month survival...
Intravascular large B-cell lymphoma (IVLBCL) is a very rare type of non-Hodgkin in which tumor cells proliferate within the lumina small blood vessels, particularly capillaries, causing clinical symptoms.1Liu C. Lai N. Zhou Y. et al.Intravascular confirmed by lung biopsy.Int J Clin Exp Pathol. 2014; 7: 6301-6306PubMed Google Scholar The presentation IVLBCL differs among geographic areas. For example, Asians more commonly present with fever, hepatosplenomegaly, thrombocytopenia, bone marrow...
PURPOSE To evaluate anticoagulant trends and clinical outcomes in the management of cancer-associated thrombosis (CAT) within Thailand, an upper-middle–income country (UMIC). METHODS This multicenter retrospective cohort study included adult patients with cancer diagnosed venous thromboembolism (VTE) hospitalized Thailand from 2017 to 2021. Anticoagulants were classified as low-molecular-weight heparin (LMWH), direct oral anticoagulants (DOACs), warfarin. Prescription assessed, followed for...
"AML with MECOM rearrangement" was recently categorized by WHO classification 2022 regardless of blast count, which included those present MDS and AML into this group. We aim to explore frequency, clinical characteristics, outcomes in subtype among Thai myeloid neoplasms. data collected from a multicenter study rearrangements were analyzed compared other subtypes. A total 15 cases rearrangement detected, 5/166 (3%) while 10/1082 (0.9%) AML. Eleven (73%) female. showed lower hemoglobin, but...
Phenytoin is a commonly prescribed antiepileptic medication for the prevention and treatment of tonic-clonic or partial seizures. Thrombocytopenia rare serious adverse effect phenytoin. This case report presents patient with severe thrombocytopenia induced by phenytoin A 63-year-old male received 300 mg/day Seven days after receiving first dose phenytoin, he was diagnosed (platelet count 44 x 10
Essential thrombocythemia (ET) involves the proliferation of megakaryocytes and platelets is associated with an increased risk thrombosis. We aimed to evaluate thrombotic risks in patients epigenetic regulator mutations generate a model predict thrombosis ET.
In patients with aplastic anemia (AA), infection-related complications are the leading cause of mortality. However, limited knowledge about predictive factors for infection in these exists. Thus, this study aimed to evaluate risk and develop a prediction model occurrence AA.
Acute myeloid leukemia (AML) is a common, challenging hematologic malignancy worldwide. Thai data on its characteristics and outcomes have never been systematically reported, to our knowledge. The objective of this study was determine the clinical features patients with AML.This prospective observational nine academic hospitals. Patients newly diagnosed AML were invited register online.A total 679 included. presence circulating peripheral blood blasts correlated high white cell count....
Bone marrow transplantation, antithymocyte globulin/cyclosporine and eltrombopag are recommended as first-line therapy of severe aplastic anemia (SAA). However, androgens could be considered front-line treatment among any patients ineligible for better methods although unsatisfactory efficacy is presented.This retrospective study aimed to evaluate response survival rate practical-based with oxymetholone.This constituted an analysis receiving a diagnosis acquired (AA) at the age 15 or over...
Purpose: This study evaluated factors that affect granulocyte-colony stimulating factor (G-CSF) adsorption in the infusion tube by measuring G-CSF concentration, rate of infusion, and volume flush solution. Methods: The concentrations all samples were measured an enzyme-linked immunosorbent assay (ELISA) using human Quantikine® ELISA kits. concentration G-CSF, administration, solution studied respectively. administration had a significantly lower percent recovery after via set used for...
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid (AML) with unique clinical presentation and prognosis. This study aimed to investigate the epidemiology, characteristics, treatments, outcomes Thai APL patients dominantly treated all-trans-retinoic acid (ATRA) combined chemotherapy-based therapy.This was an eight-year prospective, observational from nine academic hospitals in Leukemia Working Group (TALWG) Society Hematology, which included newly diagnosed patients,...
Objective: Bone marrow examination is valuable for identifying the cause of fever unknown origin (FUO) in HIV-infected patients. Based on outcomes bone patients with FUO, we aimed to develop a predictive model factors that can increase diagnostic yield examination. Design: For this retrospective cohort study, enrolled patients, aged more than 15 years and diagnosed at Songklanakarind Hospital Southern Thailand, between January 2009 December 2019. Methods: Evaluations were based aspiration,...