A5042674372- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Cytomegalovirus and herpesvirus research
- Systemic Lupus Erythematosus Research
- Influenza Virus Research Studies
- Tuberculosis Research and Epidemiology
- Pelvic floor disorders treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Urinary Tract Infections Management
- Immunodeficiency and Autoimmune Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Polyomavirus and related diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Herpesvirus Infections and Treatments
- Urinary Bladder and Prostate Research
- Infective Endocarditis Diagnosis and Management
- Infectious Diseases and Mycology
- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Immune Cell Function and Interaction
- Antimicrobial agents and applications
- Healthcare and Environmental Waste Management
- NF-κB Signaling Pathways
- Epilepsy research and treatment
- Neurological Complications and Syndromes
Ramathibodi Hospital
2014-2025
Mahidol University
2014-2025
University of Iowa Hospitals and Clinics
2009-2011
Rhode Island Hospital
2009
Providence College
2009
The aim of this study was to determine the appropriateness antibiotic initiation, selection, and duration therapy among patients in nursing homes with results a urinalysis showing urinary tract infection.
Vitamin D supplementation for infectious diseases has been discussed, but its role in COVID-19 is unclear. Therefore, this study examined the clinical outcomes of pneumonia patients who received vitamin supplementation.
Formal, large-scale, multicenter studies of invasive mould infection (IMI) in Asia are rare. This 1-year, retrospective study was designed to assess the incidence and clinical determinants IMI centers five countries (Thailand, Taiwan, Singapore, China, India). Patients treated a single year (2012) were identified through discharge diagnoses, microbiology, histopathology logs, entered based on published definitions IMI. A total 155 cases included (median age 54 years; 47.7% male). Of these,...
Abstract Background To date, no clinical study has confirmed the efficacy of routine annual vaccination in stroke patients. The primary objective was to immunologic response influenza between functional-dependence (FD) and functional-independence (FI) ischemic Median hemagglutination titers at T0 T1 Methods A prospective observational conducted 2023 2024 Ramathibodi Hospital. Old patients were screened for eligibility. Enrolled received standard doses inactivated trivalent vaccine. Data on...
Abstract Despite receiving an annual influenza vaccination, lupus patients showed a decline in immunological responses for various reasons. This study aimed to assess immune after booster- (BD) and standard-dose (SD) quadrivalent vaccine the adverse events incidence of infection among patients. A randomized controlled trial was conducted between March 2021 May 2022 at Ramathibodi Hospital. All were stratified into two groups depending on depth immunosuppressive therapy receive either BD or...
Invasive fungal diseases (IFD) are a serious threat, but physicians in Asia lack access to many advanced diagnostics mycology. It is likely that they face other impediments the management of IFD. A gap analysis was performed understand challenges Asian faced medical mycology.The Fungal Working Group (AFWG) conducted web-based survey on practices for IFD among clinicians China, India, Indonesia, Philippines, Singapore, Taiwan and Thailand.Among 292 respondents, 51.7% were infectious disease...
A large-scale surveillance is an important measure to monitor the regional spread of antimicrobial resistance. We prospectively studied prevalence and molecular characteristics clinically Gram-negative bacilli, including Escherichia coli , Klebsiella pneumoniae Acinetobacter baumannii complex (ABC), Pseudomonas aeruginosa from blood, respiratory tract, urine, sterile sites at 47 hospitals across Thailand.
Abstract Background Adult-onset immunodeficiency associated with interferon-γ autoantibody (IGA) is an emerging disease. The majority of patients require both antimicrobial and immunosuppressive treatments. However, anti-CD20 therapy not fully accessible in a resource-limited setting to date. objectives this work were study the efficacy cyclophosphamide treatment role laboratory biomarkers for disease progression monitoring. Methods A prospective pilot cohort was conducted among...
Acute respiratory failure with diffuse pulmonary opacities is an unusual manifestation following influenza vaccination. We report herein a patient chronic obstructive disease who developed fever worsening of symptoms and severe hypoxemia requiring ventilatory support shortly after Bronchoalveolar lavage was compatible acute eosinophilic pneumonia. Rapid clinical improvement observed 2 weeks systemic corticosteroid treatment, followed by radiographic at 4 weeks. No recurrence the 6-month follow-up.
Data on BK virus–associated nephropathy (BKVAN) and treatment strategy in a resource-limited country are scarce. This study aimed to evaluate epidemiology of BKVAN its situation Thailand. A retrospective analysis was conducted among adult kidney transplant recipients at Ramathibodi Hospital from October 2011 September 2016. Patients' demographic data, information transplantation, immunosuppressive therapy, cytomegalovirus virus infections, allograft outcomes were retrieved analyzed. included...
Talaromyces marneffei (T. marneffei) is an important opportunistic pathogen found in human immunodeficiency virus-positive individuals Southeast Asia, Southern China, and Northeastern India. Patients with disseminated talaromycosis commonly develop multi-organ involvement including the skin. In this report, we describe clinical presentation, investigation, management, outcome of acquired immune deficiency syndrome (AIDS) patient newly diagnosed without skin involvement.A 27-year-old male...
JC polyomavirus (JCPyV)-associated nephropathy (JCPyVAN) occurs in <3% of PVAN cases after renal transplantation. We report the first confirmed case to our knowledge JCPyVAN diagnosed by kidney biopsy early 6 months post transplant Thailand. In this report, recovery allograft function was not observed reduction immunosuppressive agents and administration intravenous immunoglobulin cidofovir. Despite persistent JCPyV viruria, no significant further decline documented at 15 transplant.
The effects of cytomegalovirus (CMV)-specific cell-mediated immunity (CMI) on CMV infection in patients with autoimmune diseases receiving immunosuppressants have not been explored. Patients active systemic lupus erythematosus (SLE) were preemptively monitored for clinically significant (CsCMVI; defined as plasma DNA loads >3 log10 IU/mL). CMV-specific CMI was assessed using an enzyme-linked immunosorbent assay (QuantiFERON-CMV [QF]) before well 1 and 3 months after intense immunosuppressive...
Invasive aspergillosis (IA) is a fatal infectious complication among immunocompromised patients. Aspergillus terreus, the fourth common species can be difficult to treat due unique resistance pattern. To date, there has been no report on safety and dose adjustment when intravenous posaconazole selected in hepatic renal impairment patient. We present rare case of use patient with invasive A. terreus pulmonary infection. our knowledge, this first IA focusing drug role therapeutic monitoring...
Objective The risk factors associated with urinary tract infections (UTIs) in patients SLE remain uncertain. We evaluated the vaginal microbiota pattern and its potential UTI-associated factors. Methods A pilot cross-sectional study of was conducted at Ramathibodi Hospital, Bangkok, Thailand, during 2019–2020. Patients’ demographic data relevant information were collected. Vaginal assessed all 10 healthy volunteers. Results Fifty-two enrolled (mean age: 46.1 years). All had that low disease...
The association between genetic background and the risk of invasive aspergillosis (IA) has not been addressed in Thailand. We conducted surveillance for IA among Thai hematologic patients. a prospective observational cohort study including moderate- to high-risk hematology patients at Ramathibodi Hospital. occurrence, relevant clinical data, analyses were assessed. Odds ratios (ORs) assessed presence selected single nucleotide polymorphism genotype using logistic regression. A total 357...
Abstract Objective: Systemic lupus erythematosus (SLE) patients receiving immunosuppressive therapy are at risk for opportunistic infections (OIs), particularly Pneumocystis pneumonia (PCP). This study aimed to evaluate the effectiveness of trimethoprim/sulfamethoxazole (TMP/SMX) as primary prophylaxis against OIs and its adverse effects in SLE low-level treatment a real-world setting. Methods: open-label randomized controlled trial enrolled Ramathibodi Hospital between May 2021 December...
Universal antifungal treatment has been recommended among hematology patients during chemotherapy to prevent invasive aspergillosis (IA) in developed countries, but it remains a significant challenge resource-limited settings. Identifying at-risk individuals could enhance clinical outcomes. A prospective pilot study was conducted at four Thai tertiary care hospitals from April 2021 January 2023, aiming assess the correlation and potential of nasal wash galactomannan (GM) as an IA predictor...