A5103060669- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Behavioral Health and Interventions
- Cancer survivorship and care
- Health Systems, Economic Evaluations, Quality of Life
- Prostate Cancer Diagnosis and Treatment
- Urinary Tract Infections Management
- Hormonal and reproductive studies
- Head and Neck Cancer Studies
- Patient-Provider Communication in Healthcare
- Genital Health and Disease
- Vitamin D Research Studies
- Prostate Cancer Treatment and Research
- Oral Health Pathology and Treatment
- Eating Disorders and Behaviors
- COVID-19 and Mental Health
- Medication Adherence and Compliance
- Bone health and osteoporosis research
- Patient Satisfaction in Healthcare
- Economic and Environmental Valuation
- Physical Activity and Health
- Blood Pressure and Hypertension Studies
- Folate and B Vitamins Research
- Sexual function and dysfunction studies
- Health Promotion and Cardiovascular Prevention
University of Bristol
2016-2025
University of Oxford
2025
NIHR Bristol Biomedical Research Centre
2017-2024
University Hospitals Bristol NHS Foundation Trust
2020-2023
National Institute for Health Research
2018-2020
MRC Epidemiology Unit
2019
University of Nottingham
2012
University of New Mexico
2012
Objectives To estimate the cost-effectiveness of a primary care intervention for male lower urinary tract symptoms (LUTS) compared with usual care. Design Economic evaluation alongside cluster randomised controlled trial from UK National Health Service (NHS) perspective 12-month time horizon. Setting Thirty NHS general practice sites in England. Participants 1077 men aged 18 or older identified bothersome LUTS. Interventions A standardised and manualised treatment LUTS was The group (n=524)...
There is increasing evidence that low levels of physical activity and diets in fruit vegetables high meat dairy products are risk factors for prostate cancer disease progression. The Prostate cancer: Evidence Exercise Nutrition Trial (PrEvENT) aimed to assess a diet intervention men undergoing radical prostatectomy localized cancer. trial included qualitative component explore the experiences participating order understand acceptability data collection methods. We report findings consider...
Lower urinary tract symptoms (LUTS) can relate to storage or voiding. In men, the prevalence and severity of LUTS increases with age, a significant impact on quality life. The majority men presenting are managed by their general practitioner (GP) in first instance, conservative therapies recommended as initial treatment. However, provision primary care is variable be time resource limited. GPs require practical resources enhance patient engagement such interventions. TRIUMPH aims determine...
Objective Dietary factors and physical activity may alter prostate cancer progression. We explored the feasibility of lifestyle interventions following radical prostatectomy for localised cancer. Design Patients were recruited into a presurgical observational cohort; prostatectomy, they offered randomisation 2×3 factorial randomised controlled trial (RCT). Setting A single National Health Service trust in South West England, UK. Participants Those with listed invited to participate....
Head and neck cancers include malignancies of the mouth, larynx oropharynx. Tobacco use alcohol consumption are associated with increased risks developing dying from head cancer. The aim this review is to examine effectiveness smoking cessation interventions on disease-related outcomes, quality life behavioural change in adults cancer oral dysplasia. Cochrane library, CINAHL, Embase, MEDLINE, PsycINFO Web Science databases will be searched for randomised controlled trials investigating...
Abstract Objective To determine whether a standardised and manualised care intervention in men primary could achieve superior improvement of lower urinary tract symptoms (LUTS) compared with usual care. Design Cluster randomised controlled trial. Setting 30 National Health Service general practice sites England. Participants Sites were 1:1 to the control arms. 1077 (≥18 years) bothersome LUTS recruited between June 2018 August 2019: 524 assigned arm (n=17 sites) 553 (n=13 sites)....
Lifestyle factors, including diet and physical activity, are associated with prostate cancer progression mortality. However, it is unclear how men would like lifestyle information to be delivered following primary treatment. This study aimed identify men's preferences for receiving information.We conducted a cross-sectional pilot best-worst discrete choice experiment which was nested within feasibility randomised controlled trial. Our aim explore of activity advice surgery localised cancer....
Conservative therapies are recommended as initial treatment for male lower urinary tract symptoms. However, there is a lack of evidence on effectiveness and uncertainty regarding approaches to delivery.
Objectives Interventions designed to improve men’s diet and physical activity (PA) have been recommended as methods of cancer prevention. However, little is known about specific factors that support adherence these health behaviour changes, which could inform theory-led PA interventions. We aimed explore in men following prostatectomy for prostate (PCa). Design, setting participants A qualitative study using semistructured interviews with men, who made changes their and/or part a factorial...
Evidence from observational studies have shown that moderate intensity physical activity can reduce risk of progression and cancer-specific mortality in participants with prostate cancer. Epidemiological also taking metformin to a reduced However, data randomised controlled trials supporting the use these interventions are limited. The Prostate cancer-Exercise Metformin Trial examines feasibility randomising diagnosed localised or locally advanced cancer modify blood glucose levels. primary...
Abstract Background Lower urinary tract symptoms (LUTS) can relate to storage or voiding. In men, the prevalence and severity of LUTS increases with age, a significant impact on quality life. The majority men presenting are managed by their General Practitioner (GP) in first instance, conservative therapies recommended as initial treatment. However, provision primary care is variable be time resource limited. GPs require practical resources enhance patient engagement such interventions....