A5004042631- Migraine and Headache Studies
- Stroke Rehabilitation and Recovery
- Vestibular and auditory disorders
- Action Observation and Synchronization
- Functional Brain Connectivity Studies
- Sympathectomy and Hyperhidrosis Treatments
- Botulinum Toxin and Related Neurological Disorders
- Cerebral Venous Sinus Thrombosis
- Motor Control and Adaptation
- Virtual Reality Applications and Impacts
- Spatial Neglect and Hemispheric Dysfunction
- Neuroscience of respiration and sleep
- Cystic Fibrosis Research Advances
- Visual perception and processing mechanisms
- Glaucoma and retinal disorders
- Transcranial Magnetic Stimulation Studies
- Spinal Cord Injury Research
- Cerebral Palsy and Movement Disorders
- Multisensory perception and integration
- Psychosomatic Disorders and Their Treatments
- Ophthalmology and Eye Disorders
- Muscle activation and electromyography studies
- Intracranial Aneurysms: Treatment and Complications
- Hallucinations in medical conditions
- Neurosurgical Procedures and Complications
University of Lausanne
2020-2024
Sapienza University of Rome
2016-2023
University Hospital of Lausanne
2020-2023
New York Proton Center
2020
American Headache Society
2020
University of Geneva
2020
Despite the tight coupling between sensory and motor processing for fine manipulation in humans, it is not yet totally clear which specific properties of fingers are mapped precentral postcentral gyrus. We used fMRI to compare morphology, connectivity, encoding tactile finger representations (FRs) gyrus 25 5-fingered participants (8 females). Multivoxel pattern structural functional connectivity analyses demonstrated existence distinct FRs within both gyrus, integrating finger-specific...
The continuous stream of multisensory information between the brain and body during body-environment interactions is crucial to maintain updated representation perceived dimensions parts (metric representation) space around (the peripersonal space). Such flow signals often limited by upper limb sensorimotor deficits after stroke. This would suggest presence systematic distortions metric in chronic patients with persistent deficits. We assessed 60 stroke unilateral motor deficits, comparison...
Simple multisensory manipulations can induce the illusory misattribution of external objects to one's own body, allowing experimentally investigate body ownership. In this context, ownership has been conceptualized as result online Bayesian optimal estimation probability that one object belongs from congruence inputs. This idea highly influential, it provided a quantitative basis bottom-up accounts self-consciousness. However, empirical evidence fully supporting view is scarce, optimality...
Repetitive focal muscle vibration (rMV) is known to promote neural plasticity and long-lasting motor recovery in chronic stroke patients. Those structural functional changes within the network underlying occur very first hours after stroke. Nonetheless, our knowledge, no rMV-based studies have been carried out acute patients so far, clinical benefit of rMV this phase yet be determined. The aim randomized double-blind sham-controlled study investigate short-term effect on Out 22 patients, 10...
Background Migraine affects how the brain processes sensory information at multiple levels. The aberrant integration of visual and somatosensory stimuli is thought to underlie Alice in Wonderland Syndrome, a disorder often reported as being associated with migraine. However, there still lack knowledge about epidemiology this syndrome migraineurs association between Syndrome episodes migraine attacks. Therefore, we conducted prospective cohort study systematically evaluate prevalence clinical...
The Alice in Wonderland syndrome (AIWS) is a transient neurological disturbance characterized by sensory distortions most frequently associated with migraine adults. Some lines of evidence suggest that AIWS and might share common pathophysiological mechanisms, therefore we set out to investigate the distinct neurophysiological alterations these conditions migraineurs.We conducted case-control study acquiring resting-state fMRI data from 12 patients AIWS, typical aura (MA) 24 age-matched...
Alice in Wonderland Syndrome (AIWS) is a rare perceptual disorder characterized by an erroneous perception of the body or surrounding space. AIWS may be caused different pathologies, ranging from infections to migraine. We present case 54-year-old man, with long-time history migraine without aura, diagnosed due glioblastoma located left temporal–occipital junction. To date, this first glioblastoma. This suggests that exclude aura-mimic phenomena, careful diagnostic workup should always...
Genetic mutations of sporadic hemiplegic migraine (SHM) are mostly unknown. SHM pathophysiology relies on cortical spreading depression (CSD), which might be responsible for ischemic brain infarction. Cystic fibrosis (CF) is caused by a monogenic mutation the chlorine transmembrane conductance regulator ( CFTR ), possibly altering excitability. We describe case patient with CF, who had migrainous stroke during an attack. A 32‐year‐old Caucasian male was diagnosed heterozygotic delta...
Chronic migraine (CM) is often complicated by medication overuse headache (MOH) and psychiatric comorbidities that may influence the clinical outcome. This study aimed to investigate relationship between effect of transcranial direct current stimulation (tDCS) in patients with CM or without MOH. We recruited 16 consecutive who had an unsatisfactory response at least three pharmacological preventive therapies. They were treated anodal right-prefrontal cathodal occipital tDCS (intensity: 2 mA,...
Abstract The experience of owning a body (body ownership, BO) and the perception our dimensions (metric representation, mBR) depend on integration multisensory cues. As human sensory system is subjected to decline along lifespan, encompassing all modalities, we hypothesize that may be different in older, as compared young adults. Here, investigate this hypothesis by comparing processing underlying BO mBR healthy older (> 65 years) individuals. First, applied rigorous computational...
Stroke patients often experience alterations in their subjective feeling of ownership for the affected limb, which can hinder motor function and interfere with rehabilitation. In this study, we aimed at disentangling complex relationship between sensory impairment, body (BO), control stroke patients.
After experiencing brain damage, stroke patients commonly suffer from motor and sensory impairments that impact their ability to perform volitional movements. Visuo-proprioceptive integration is a critical component of voluntary movement, allowing for accurate movements sense ownership over one's body. While recent studies have increased our understanding the balance between visual compensation proprioceptive deficits in patients, quantitative methods studying multisensory are still lacking....
Abstract Background the Alice in Wonderland syndrome (AIWS) is a transient neurological disturbance characterized by visual and somatosensory misperceptions most frequently associated with migraine. The heterogeneity of etiologies techniques applied to investigate reported cases have so far prevented draw strong conclusions about origin AIWS symptoms. Some lines evidence suggest that migraine might share common pathophysiological mechanisms, therefore we set out distinct neurophysiological...