A5088516260- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Myasthenia Gravis and Thymoma
- Lung Cancer Treatments and Mutations
- Tracheal and airway disorders
- Soft tissue tumor case studies
- Congenital Diaphragmatic Hernia Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Sarcoma Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- IgG4-Related and Inflammatory Diseases
- Medical Imaging and Pathology Studies
- Neuroblastoma Research and Treatments
- Neuroendocrine Tumor Research Advances
- Trauma Management and Diagnosis
- Melanoma and MAPK Pathways
- Soft tissue tumors and treatment
- Teratomas and Epidermoid Cysts
- Occupational and environmental lung diseases
- Lymphoma Diagnosis and Treatment
- Genetic and Kidney Cyst Diseases
- Gestational Trophoblastic Disease Studies
- PI3K/AKT/mTOR signaling in cancer
Ruhrlandklinik
2021-2024
Lungenklinik Köln-Merheim
2024
Witten/Herdecke University
2023-2024
University of Duisburg-Essen
2022-2024
Leiomyoma en sik kadin genital sisteminde olmak uzere herhangi bir bolgede bulunabilen benign duz kas tumorudur. Leiomyomalar oral kavitede yaygin olmamakla beraber dil, dudak ve palatinal mukozada izlenebilir. Bu olgu sunumunun amaci leiomyoma saptanan bayan hastayi sunarak literatur taranmasidir. 35 yasinda hastada sag mandibular molar vestibul alveol mukozasinda yaklasik yildir sinirli, asemptomatik yumusak doku kitlesi mevcut oldugu saptanmistir. Lokal anestezi ile eksizyonel biyopsi...
Objective: Uterine carcinosarcoma (UCS) is a rare but highly aggressive malignancy with biphasic growth pattern. This morphology can be attributed to epithelial-mesenchymal transition (EMT) that often associates tumor invasion and metastasis. Accordingly, we analyzed novel patient-derived preclinical model explore whether EMT potential target in UCS. Methods: A UCS cell line (PF338) was established from the malignant pleural effusion of 59-year-old patient at time disease progression....
The use of Isolated lung perfusion (ILP), combined with medical imaging modalities such as positron emission tomography-computed tomography (PET/CT), provides real-time visualization tumors in ventilated and perfused vital tissue. This experiment intends to show the feasibility benefits using ILP PET/CT imaging. Following surgery on a 49-year-old male, his left lower lobectomy specimen, which held typical carcinoid tumor, was preserved normothermic ILP. Gallium-68-Edotreotide...
Spitzoid melanoma is a rare malignancy with histological characteristics similar to Spitz nevus. It has diverse genetic background and in adults, similarly grim clinical outcome as conventional malignant melanoma. We established spitzoid cell line (PF130) from the pleural effusion sample of 37-year-old male patient. found that carries MEK1 mutation (pGlu102_Lys104delinsGln) belongs RAF- phosphorylation-independent subgroup alternations supposedly insensitive allosteric MEK inhibitors. The...
Transpulmonary embolisation (TPE) using degradable starch microspheres (DSM) is a potential approach to treat pulmonary metastases. However, there paucity of detailed information on perfusion dynamics. The aim this study was establish human ex vivo isolated lung (ILP) model observe and evaluate the effects DSM-TPE in near-physiologic setting.ILP carried out six surgically resected lobes. At baseline, computed tomography (CT), including CT imaging (CTPI), histopathological sampling were...
Lung volume reduction surgery (LVRS) is an established treatment approach for patients with severe pulmonary emphysema, enhancing lung function and quality of life in selected patients. Functional benefits outcomes after uni- versus bilateral remain a topic debate.
Abstract Background Whole lung transpulmonary chemoembolization using a combination of doxorubicin (DXO) and degradable starch microspheres (DSM-TPCE) might be promising treatment option in soft tissue sarcoma. To pave the way for clinical studies, this study aimed to evaluate short-term effects DSM-TPCE with DXO an ex vivo isolated perfusion (ILP) model. Methods Nine specimens retrieved from patients undergoing lobectomy underwent ILP. In groups three, were either treated sole DXO, DSM, or...
Background: Emphysema patients, who are candidates for lung volume reduction surgery (LVRS) usually present with an extensive smoking history and thus have increased risk lung. The incidence of pulmonary nodules in emphysematous lungs is high. We therefore aimed to analyse the histological findings our LVRS program. Methods: conducted a retrospective review all patients underwent between 2016 2018. Data concerning preoperative workup, 30 days mortality histopathological analysed. Results:...