A5037716609- Colorectal Cancer Screening and Detection
- Microscopic Colitis
- Colorectal Cancer Surgical Treatments
- Celiac Disease Research and Management
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Eosinophilic Esophagitis
- Diverticular Disease and Complications
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- AI in cancer detection
- Anorectal Disease Treatments and Outcomes
- Whipple's Disease and Interleukins
- Colorectal and Anal Carcinomas
- Congenital Anomalies and Fetal Surgery
- Gastrointestinal Bleeding Diagnosis and Treatment
- Clinical Nutrition and Gastroenterology
- Hepatocellular Carcinoma Treatment and Prognosis
- Gene expression and cancer classification
- Radiomics and Machine Learning in Medical Imaging
- Genetic factors in colorectal cancer
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Esophageal and GI Pathology
- Cancer, Lipids, and Metabolism
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Policlinico San Matteo Fondazione
2020-2025
University of Pavia
2014-2024
Azienda di Servizi alla Persona di Pavia (Italy)
2022
Coeliac UK
2017
Abstract Background Computer-aided detection (CADe) increases adenoma in primary screening colonoscopy. The potential benefit of CADe a fecal immunochemical test (FIT)-based colorectal cancer (CRC) program is unknown. This study assessed whether use the rate (ADR) FIT-based CRC program. Methods In multicenter, randomized trial, FIT-positive individuals aged 50–74 years undergoing colonoscopy, were (1:1) to receive high definition white-light (HDWL) with or without real-time deep-learning by...
Villous atrophy (VA) of the small bowel is mainly related to coeliac disease (CD), whose diagnosis made on basis positive endomysial/tissue transglutaminase antibodies while a gluten-containing diet in vast majority patients. However, VA can also occur other conditions epidemiology little known. Our aim was study and clinical features these rare enteropathies.Clinical laboratory data all patients with directly diagnosed our centre last 15 years were collected statistically analysed.Between...
Several randomized clinical trials comparing different bowel preparations (BP) have shown similar efficacy; however, there is a lack of real-world studies on this topic.
The ileocecal valve (ICV) is one of the most difficult locations for endoscopic submucosal dissection (ESD) because limited scope maneuverability, presence fatty tissue, and particular anatomic features [1[1]]. Consequently, en bloc R0 resection rates are reported to be lower than other [2[2]] [3[3]]. Lesions covering ≥75% ICV, involvement anal lip or more two sites on ICV risk factors poor outcomes [4[4]]. Traction-assisted ESD has recently emerged as a technique that facilitates ESD,...
An accurate histological diagnosis of colorectal cancer is essential for promptly establishing appropriate therapeutic management. Furthermore, nowadays larger samples are needed to evaluate immunological and genetic panels. For malignant lesions that cannot be removed endoscopically, the European Guidelines recommend taking six carefully targeted biopsies from suspected focus [1]. Despite advancements in endoscopic imaging, a retrospective study 962 patients undergoing adenocarcinoma...
Percutaneous endoscopic gastrostomy is performed to gain enteral nutritional access in patients with impaired swallowing. However, gastrocutaneous fistula (GCF) may persist up 25% of cases following tube removal [11]. Endoscopic submucosal dissection (ESD) re-epithelialize the fistulous tract, combined closure using an over-the-scope (OTS) clip, has been reported as a safe and effective approach for managing persistent GCF [22] [33] [44]. A twin grasper commonly used pull into OTS clip...
Coeliac disease is a chronic enteropathy requiring close follow-up. However, the best way to follow up coeliac patients has not yet been established. In last 14 years, we have offering thorough series of periodical examinations including histological re-evaluation at 12-18 months.The notes all attending our clinic between September 1999 and March 2013 were examined.Data from 317 adult collected. Duodenal biopsy showed lack satisfactory response in 25/317 patients; endomysial antibodies still...
: Serum alpha-fetoprotein (AFP) is a recognized affordable oncological marker in patients with hepatocellular carcinoma (HCC). However, AFP's prognostic role has been assessed mainly after specific treatments, and no unanimously cut-offs have identified. The aim of this study to investigate the different basal AFP on survival HCC course.
Abstract Follow-up modalities for adult coeliac patients remain controversial. Non-invasive markers to identify on a gluten-free diet (GFD) with persistence of villous atrophy (VA) are still lacking. We aim develop score stratify GFD according their risk having persistent VA and tailor follow-up accordingly. The clinical notes over 700 attending our unit (September 1999–November 2018) were retrospectively examined. A total 273 histological performed 12–24 months after diagnosis selected....
The utility of the 7 level Marsh-Oberhuber classification mucosal damage in patients with coeliac disease has recently been criticised. Analysis duodenal biopsies dissecting microscopy is an unsophisticated method that, however, provides useful information cases frank villous atrophy. In last 15 years, we have always analysed before sending them to pathology department for histology. If results and traditional histology were comparable, feel that would be strong evidence grading histological...
Aims The American Cancer Society reduced the age of CRC screening from 50 to 45 years in 2018 response a recent increase early onset-CRC1. Our primary aim was analyse prevalence colorectal preneoplastic and neoplastic lesions patients under referred for colonoscopy our center. secondary identify possible risk factors development these lesions.
Aims Computer Aided Detection (CADe) increases adenoma detection in primary screening colonoscopy. The potential benefit of CADe FIT-based programs, where the prevalence neoplasia is high, has never been evaluated.