- Nutrition and Health in Aging
- Pain Management and Opioid Use
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Reproductive Health and Technologies
- Reproductive Biology and Fertility
- Liver Disease Diagnosis and Treatment
- Pain Mechanisms and Treatments
- Pain Management and Placebo Effect
- Bone health and osteoporosis research
- COVID-19 Clinical Research Studies
- Opioid Use Disorder Treatment
- Dysphagia Assessment and Management
- Pharmacological Effects and Toxicity Studies
- Laser Applications in Dentistry and Medicine
- Gallbladder and Bile Duct Disorders
- Ethics and Legal Issues in Pediatric Healthcare
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Stroke Rehabilitation and Recovery
- Cardiovascular Syncope and Autonomic Disorders
- Endometriosis Research and Treatment
- Botulinum Toxin and Related Neurological Disorders
- Venous Thromboembolism Diagnosis and Management
- Hepatocellular Carcinoma Treatment and Prognosis
Policlinico San Matteo Fondazione
2012-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2024
Corvid Technologies (United States)
2021
CARE Fertility
2020
Ospedale Civile di Voghera
2018
University of Pavia
2012-2017
Azienda di Servizi alla Persona di Pavia (Italy)
2013
Reproductive Science Center
2007-2009
Saint Louis University
1983-1984
Little is known regarding coronavirus disease 2019 (COVID-19) clinical spectrum in non-Asian populations. We herein describe the impact of COVID-19 on liver function 100 consecutive patients (median age 70 years, range 25-97; 79 males) who were admitted to our internal medicine unit March 2020. retrospectively assessed tests, taking into account demographic characteristics and outcome. A patient was considered as having injury when alanine aminotransferase (ALT) > 50 mU/ml, gamma-glutamyl...
Background: Two-thirds of older people suffer from chronic pain and finding valid treatment options is essential. In this 1-yearlong investigation, we evaluated the efficacy safety prolonged-release oxycodone–naloxone (OXN-PR) in patients aged ≥70 (mean 81.7) years. Methods: open-label prospective study, with moderate-to-severe noncancer were prescribed OXN-PR for 1 year. The primary endpoint was proportion who achieved ≥30% reduction intensity after 52 weeks treatment, without worsening...
The actions of clomiphene, tamoxifen, and 17β- estradiol were studied in an isolated avian granulosa cell system during short term incubations. A dose-dependent inhibition ovine LH-enhanced progesterone production was observed for all three compounds, with IC50 3 × 10−6m maximal (95%) at 5 10−5m. similar found when cells stimulated by either 8-bromo-cAMP or forskolin. Neither clomiphene nor tamoxifen had inhibitory effect on the conversion pregnenolone to progesterone, a step that blocked...
Purpose: Chronic pain is highly prevalent in older adults. Increasing evidence indicates strong opioids as a valid option for chronic management geriatrics. The aim of this study was to evaluate efficacy and safety low-dose oral prolonged-release oxycodone–naloxone (OXN-PR) patients aged ≥70 years. Methods: This open-label prospective assessed naïve presenting with moderate-to-severe pain. Patients were prescribed OXN-PR at an initial dose 10/5 mg/day 28 days. In case insufficient analgesia,...
Introduction. Recalcitrant skin ulcers are a major burden in elderly patients. Specifically, chronic wounds result significant morbidity and mortality have profound economic impact. Pulsed electromagnetic fields (PEMFs) proved to be promising therapy for wound healing. Here we describe the first reported case of an innovative PEMF therapy, Emysimmetric Bilateral Stimulation (EBS), used successfully treat refractory two fragile Case Presentation. Two patients developed multiple ulcerations....
Abstract Preliminary evidence supports the notion that COVID-19 patients may have an increased susceptibility to develop venous thromboembolism (VTE). However, magnitude of this association still needs be defined. Furthermore, clinical predictors thrombogenesis, and relationship with inflammatory status are currently unknown. On basis, we conducted a retrospective, observational study on 259 consecutive admitted academic tertiary referral hospital in Northern Italy between March 19th April...
: Serum alpha-fetoprotein (AFP) is a recognized affordable oncological marker in patients with hepatocellular carcinoma (HCC). However, AFP's prognostic role has been assessed mainly after specific treatments, and no unanimously cut-offs have identified. The aim of this study to investigate the different basal AFP on survival HCC course.
In the last decade, development of different methods brain stimulation by electromagnetic fields (EMF) provides a promising therapeutic tool for subjects with impaired cognitive functions. Emisymmetric bilateral (EBS) is novel and innovative EMF stimulation, whose working principle to introduce very weak noise-like stimuli through trigger self-arrangements in cortex treated subjects, thereby improving faculties. The aim this pilot study was investigate patients impairment effectiveness EBS...
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death. Abdominal ultrasound (US) by far the most widely used first-level exam for diagnosis HCC. We aimed to assess whether different patterns were related tumor prognosis. retrospectively reviewed all patients with new HCC (single nodule) and undergoing radiofrequency thermal ablation (RFTA) at our clinic between January 2009 December 2021. Patients classified according four patterns: 1A, single capsulated nodule; 1B, well...
Skin ulcers are a common issue in the elderly, as physiological loss of skin elasticity, alterations microcirculation, and concomitant chronic diseases typically occur advanced age, thereby predisposing to these painful lesions. Wound-related pain is often associated with negatively impacts both patient's quality life and, indirectly, wound healing. Pain management an ongoing remains underestimated under-treated this fragile population. Recent guidelines suggest use opioids frontline...