- Cardiovascular Conditions and Treatments
- Cardiac Arrhythmias and Treatments
- Cardiovascular Effects of Exercise
- Cardiac electrophysiology and arrhythmias
- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Congenital heart defects research
- Atrial Fibrillation Management and Outcomes
- Heart Rate Variability and Autonomic Control
- Cardiovascular Function and Risk Factors
- Cardiac tumors and thrombi
- Vascular anomalies and interventions
- Viral Infections and Immunology Research
- Veterinary Oncology Research
- Sarcoma Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Cancer-related molecular mechanisms research
- Venous Thromboembolism Diagnosis and Management
- Coronary Artery Anomalies
- Streptococcal Infections and Treatments
- Respiratory Support and Mechanisms
- Veterinary Pharmacology and Anesthesia
- Toxoplasma gondii Research Studies
- Galectins and Cancer Biology
University of Bologna
2016-2024
University of Pavia
2020-2023
Stazione Sperimentale del Vetro
2013-2016
University of Bari Aldo Moro
2016
University of Teramo
2016
University of Padua
2016
Studies on the use of amiodarone or sotalol are limited in dogs. Therefore, this study aimed to provide data efficacy and safety these drugs dogs with ventricular tachyarrhythmia (VT) and/or supraventricular (SvT).
Background The prognostic relevance of left atrial (LA) morphological and functional variables, including those derived from speckle tracking echocardiography (STE), has been little investigated in veterinary medicine. Objectives To assess the value several echocardiographic with a focus on LA variables dogs myxomatous mitral valve disease (MMVD). Animals One‐hundred fifteen different breeds MMVD. Methods Prospective cohort study. Conventional morphologic echo‐Doppler areas volumes,...
Background The assessment of left atrial ( LA ) function by 2‐dimensional speckle tracking echocardiography STE holds important clinical implications in human medicine. Few similar data are available dogs. Objectives To assess dogs with and without myxomatous mitral valve disease MMVD ), analyzing areas, systolic function, strain. Animals One hundred fifty were divided according to the American College Veterinary Internal Medicine classification heart failure: 23 class A, 52 B1, 36 B2, 39 C...
Dogs with myxomatous mitral valve disease (MMVD) can experience progressive renal tubular damage and dysfunction. The prevalence of is not known in dogs stable MMVD.To evaluate MMVD by evaluation urinary neutrophil gelatinase-associated lipocalin (NGAL).Ninety-eight grouped according to the American College Veterinary Internal Medicine (ACVIM) staging (group B1, n = 23; group B2, 27; C + D, 48) 46 healthy dogs.Multicenter prospective observational study. Serum urine chemistry including NGAL...
In dogs, myocardial injury (MI) is a poorly characterized clinical entity; therefore, this study aimed to provide detailed description of dogs affected by condition.
Atrial fibrillation secondary to dilated cardiomyopathy (DCM) frequently affects large-breed dogs. The aim of the present study was identify risk factors for development atrial in dogs different breeds with an echocardiographic diagnosis DCM.In this multicenter retrospective study, we searched electronic databases five cardiology referral centers DCM. A comparison clinical and variables performed between developing those not ability distinguish these two groups evaluated by receiver...
Transient myocardial thickening (TMT) in cats is a poorly characterized clinical entity. Therefore, this study aimed to provide descriptions of additional diagnosed with phenomenon. For multicenter observational retrospective study, TMT were searched three medical databases (2014–2023). was defined for at least two echocardiograms showing an increased end-diastolic left ventricular wall thickness (LVWTd; i.e., ≥ 6 mm) presentation and subsequent echocardiographic normalization (i.e., LVWTd <...
The Lorenz plot (LP), a graphical representation of heart rate variability, has been poorly studied in dogs to date. present study aimed describe the graphic features LP with sinus rhythm (SR) and tachyarrhythmias, analyze usefulness its pattern recognition. One hundred nineteen canine Holter recordings were retrospectively evaluated. Cardiac rhythms classified as: SR; SR frequent (>100) premature ectopies (atrial, SR-APCs; ventricular, SR-VPCs; atrial SR-APCs-VPCs); fibrillation (AF); AF...
Abstract Preliminary evidence supports the notion that COVID-19 patients may have an increased susceptibility to develop venous thromboembolism (VTE). However, magnitude of this association still needs be defined. Furthermore, clinical predictors thrombogenesis, and relationship with inflammatory status are currently unknown. On basis, we conducted a retrospective, observational study on 259 consecutive admitted academic tertiary referral hospital in Northern Italy between March 19th April...
Abstract Background Information regarding the frequency of L waves and their prognostic relevance in dogs with secondary atrial fibrillation (AF) is limited. Hypothesis/Objectives To determine whether occur ascertain role, as well role other clinical echocardiographic variables AF. Animals Fifty‐five AF associated myxomatous mitral valve disease or dilated cardiomyopathy. Methods Retrospective, multicenter observational study. In addition to analysis, variables, including type antiarrhythmic...
Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker of tubular damage, and its elevation has been described in human canine cardiorenal syndrome. The aim was to evaluate the association between echocardiographic indexes urine NGAL (uNGAL) uNGAL normalized creatinine (uNGALC) dogs with MMVD. This multicentric prospective cross-sectional study. A total 77 MMVD at different ACVIM stages were included. All underwent echocardiography, serum chemistry, urinalysis. Echocardiographic...
Galectin-3 (Gal-3) is a lectin associated with fibrosis and inflammation, increased circulating concentrations are considered risk factor for atrial fibrillation (AF) in humans. This retrospective study aimed to evaluate the serum concentration of Gal-3 dogs cardiac disease, both without AF. Dogs AF congenital acquired heart diseases were selected, while clinically healthy but served as controls. We statistically compared Gal-3, assessed using commercial canine-specific ELISA kit, among...
Abstract OBJECTIVE To determine the sensitivity, specificity, and interobserver variability of survey thoracic radiography (STR) for detection heart base masses (HBMs) in dogs. DESIGN Retrospective case-control study. ANIMALS 30 dogs with an HBM 120 breed-matched control (60 healthy 60 disease no HBM). PROCEDURES In a blinded manner, 2 observers (designated as A B) evaluated STR views from each dog mass-like opacity cranial to heart, tracheal deviation, cardiomegaly, findings suggestive...
Abstract Background Atrial fibrillation (AF) occurs in dogs with myxomatous mitral valve disease (MMVD) as a consequence of left atrial (LA) dilatation, and it affects survival quality life. Objectives To evaluate the usefulness echocardiography predicting first occurrence AF MMVD. Animals Forty‐four client‐owned MMVD, 22 that developed AF, maintained sinus rhythm. Methods Retrospective observational study. Medical databases were reviewed for during year after diagnosis MMVD (AF group). The...
Objectives Normal features of the ST segment are poorly characterised in dogs. This study aimed to describe characteristics a population healthy Materials and Methods Medical records were reviewed identify dogs that underwent an electrocardiogram. Several qualitative parameters evaluated: presence/absence deviation, type deviation (depression/elevation) morphological patterns depression (horizontal, downsloping, upsloping sagging) elevation concave convex). Moreover, amplitude...
Specific microRNAs expressions may accurately characterize different stages of canine myxomatous mitral valve disease. This preliminary pilot study aimed to (1) describe the clinical and echocardiographic parameters Cavalier King Charles Spaniels affected by disease at American College Veterinary Internal Medicine (ACVIM) (B1, B2 C) healthy control group (ACVIM A), comparing collected during first examination (T0) end follow-up (T1); (2) assess association between values T1 expression...
Abstract Background No previous study has evaluated the accuracy of a six‐lead smartphone‐based electrocardiographic (s‐ECG) device in dogs. Methods This was prospective multicentre study. Patients referred for cardiologic consultation were selected. In each patient, 30‐second electrocardiogram simultaneously acquired with novel s‐ECG and standard ECG machine (st‐ECG). A board‐certified cardiologist recording. Nineteen variables, including heart rate rhythm, as well quantitative qualitative...
Plasmatic dimethylarginines, asymmetric dimethylarginine (ADMA) and symmetric (SDMA) are considered biomarkers of endothelial renal dysfunction, respectively, in humans. We hypothesize that plasmatic concentration dimethylarginines dogs with myxomatous mitral valve disease (MMVD) is influenced by heart stage. Eighty-five client-owned MMVD, including 39, 19, 27 ACVIM stages B1, B2, C+D, a control group 11 clinically healthy were enrolled. A prospective, multicentric, case-control study was...