A5044797791- Genetic and phenotypic traits in livestock
- Cardiovascular Conditions and Treatments
- Animal Genetics and Reproduction
- Congenital Heart Disease Studies
- Human-Animal Interaction Studies
- Skin and Cellular Biology Research
- Neurological diseases and metabolism
- Genetic Mapping and Diversity in Plants and Animals
- T-cell and Retrovirus Studies
- Meat and Animal Product Quality
- Congenital heart defects research
- Animal Disease Management and Epidemiology
- Genetic diversity and population structure
- Wildlife Ecology and Conservation
- Mycobacterium research and diagnosis
- Virus-based gene therapy research
- Genomics and Phylogenetic Studies
- Cardiovascular Function and Risk Factors
- Animal Nutrition and Physiology
- Vector-Borne Animal Diseases
- Identification and Quantification in Food
- Livestock and Poultry Management
- Genetic Syndromes and Imprinting
- Cardiomyopathy and Myosin Studies
- Wnt/β-catenin signaling in development and cancer
University of Milan
2015-2025
Istituto Sperimentale per la Zootecnia
1995
Istituto di Biologia e Biotecnologia Agraria
1993
The epidemiology of Congenital Heart Diseases (CHDs) has changed over the past twenty years. This study aimed to evaluate prevalence CHDs in population dogs recruited a single referral center (RC); compare epidemiological features screened breeds (Boxers) versus non-screened (French and English Bulldogs, German Shepherds); investigate association with CHDs; determine popularity volatility 20-year period; analysed trends most popular overall new-born registered Italian Kennel Club (IKC) from...
Background Two mutations in the MYBPC 3 gene have been identified M aine C oon ( MCO ) and R agdoll RD cats with hypertrophic cardiomyopathy HCM ). Objective This study examined frequency of these A74T polymorphism to describe their worldwide distribution correlation echocardiography. Animals: 1855 representing 28 breeds random‐bred worldwide, which 446 underwent echocardiographic examination. Methods is a prospective cross‐sectional study. Polymorphisms were genotyped by Illumina VeraCode...
Abstract Background The cat has one common blood group with two major serotypes, type A that is dominant to B. rare AB may also be allelic and suspected recessive Cat antigens are defined, N-glycolylneuraminic acid (NeuGc) associated N-acetylneuraminic (NeuAc) enzyme cytidine monophospho-N-acetylneuraminic hydroxylase ( CMAH ) determines the sugar bound red cell by converting NeuAc NeuGc. Thus, mutations in cause B types. Results Genomic sequence of from eight cats cDNA four representing all...
Abstract Through thousands of years breeding and strong human selection, the dog ( Canis lupus familiaris ) exists today within hundreds closed populations throughout world, each with defined phenotypes. A singular geographic region broad diversity in breeds presents an interesting opportunity to observe potential mechanisms breed formation. Italy claims 14 internationally recognized breeds, numerous additional local varieties. To determine relationship among Italian populations, we...
Bees are crucial for food production and biodiversity. However, extreme weather variation harsh winters the leading causes of colony losses low honey yields. This study aimed to identify most important features predict Total Honey Harvest (THH) by combining machine learning (ML) methods with climatic conditions environmental factors recorded from winter before during harvest season. The initial dataset included 598 THH records collected five apiaries in Lombardy (Italy) spring summer 2015...
Summary Seventeen commercial and research laboratories participated in two comparison tests under the auspices of International Society for Animal Genetics to develop an internationally tested, microsatellite‐based parentage identification panel domestic cat ( Felis catus ). Genetic marker selection was based on polymorphism information content allele ranges from seven random‐bred populations n = 261) USA, Europe Brazil eight breeds 200) USA. Nineteen microsatellite markers were included...
Autosomal-dominant polycystic kidney disease (AD-PKD) is common in Persians and Persians-related breeds. The aims of this study were to evaluate the sensitivity specificity early ultrasound examination compare genetic testing for diagnosis. Sixty-three seven Exotic Shorthairs considered. All underwent ultrasonographic (polymerase chain reaction/restriction fragment length polymorphism (PCR/RFLP) assay) between 2.5 3.5 months age (10-14 weeks). With ultrasound, 41.4% showed renal cysts, while...
Abstract The island inhabitants of Sardinia have long been a focus for studies complex human traits due to their unique ancestral background and population isolation reflecting geographic cultural restriction. Population isolates share decreased genomic diversity, increased linkage disequilibrium, inbreeding coefficients. In many regions, dogs humans exposed the same natural artificial forces environment, growth, migration. Distinct dog breeds arisen through human-driven selection...
The present study aimed to evaluate the effects of probiotic strain Lactobacillus acidophilus D2/CSL (CECT 4529) on nutritional condition and faecal quality in cats.Ten healthy adult cats from same cattery were included (aged >9 months; male:female sex ratio=3:7). animals randomly assigned a control group (CTR; n=5; male:female=1:4; room 1: 16 m2) treated (LACTO; male:female=2:3; 2: receiving commercial dry diet. LACTO diet was supplemented with (5 x 109 cfu/kg feed at least). A five-week...
SUMMARY Polymorphism of the bovine DRB, DQA, DQB, DYA, DOB and DIB genes was investigated using restriction fragment length polymorphism (RFLP) analysis, isoelectric focusing (IEF), class II serology polymerase chain reaction (PCR) based typing techniques. The simultaneous application multiple techniques characterization resulted in a greatly enhanced picture regions. Thirty‐eight IIa (DR‐DQ) 5 lib (DYA‐DOB‐DIB) haplotypes were defined. It found that IEF types associated with DRB3 defined by...
Very little research into genetic diversity of Italian native dog breeds has been carried out so far. In this study we aimed to estimate and compare the four shepherd breeds: Maremma, Bergamasco, Lupino del Gigante Oropa shepherds. Therefore, some cosmopolitan breeds, which have widely raised in Italy for a long time past, also considered check possible influence these populations on autochthonous here. A total 212 individuals, belonging 10 different were sampled genotyped using 18 autosomal...
Seven autochthonous Italian cattle breeds bred in the alpine area (Aosta Black Pied, Aosta Red Chestnut, Oropa Grey Alpine, Rendena and Burlina) were investigated order to characterise their genetic structure study phylogenetic origin. Two from Germany (Original German Brown Holstein) four Switzerland (Simmental, Herens, Evolene Swiss) included determine diversity existing among local breeds, similar on other side of Alps well known Holstein. Seventeen microsatellites, internationally...
Background The aim of the present study was to investigate effects Lactobacillus acidophilus D2/CSL (CECT 4529) probiotic strain on nutritional status and faecal microbiological parameters in a group purebred boxers. Methods Forty healthy adult boxer dogs were randomly assigned treated (LACTO) receiving commercial diet supplemented with L final concentration 5.0 x 10 9 colony‐forming unit/kg food, control (CTR) same but without (placebo). Nutritional (body weight, skinfold thickness, body...
Taurine deficiency predisposes to the development of nutritional dilated cardiomyopathy and is widespread in dogs fed with non-traditional diets. However, Golden retrievers show lower plasma taurine concentration an impaired systolic function compared breeds same size morphotype. For these reasons, it can be difficult classify a subject from cardiological point view, risk considering as pathological characteristics that completely normal this breed. This cross-sectional multicenter study....
Italy is home to several populations of native dogs that reside only in certain demographic regions. Such dog have not been under tight selection by humans and, as such, never officially recognised breeds. One such population the ‘Cane Fonnese’ or Fonni’s Dog, which features uniform morphologic and behavioural traits reproduce across generations, thus qualifying Dog a true breed eligible for recognition national international registries. The examined present work Sardinia, where they are...
Livestock guarding dogs are a valuable adjunct to the pastoral community. Having been traditionally selected for their working ability, they fulfil function with minimal interaction or command from human owners. In this study, population structure and genetic differentiation of three Italian livestock guardian breeds (Sila's Dog, Maremma Abruzzese Sheepdog Mannara's Dog) functionally physically similar (Cane Corso, Central Asian Shepherd Dog Caucasian Dog), totalling 179 unrelated at second...
Abstract The epidemiology of Congenital Heart Diseases (CHDs) has changed over the past twenty years. We evaluated prevalence CHDs in population dogs recruited a single referral center (RC); compared epidemiological features screened breeds (Boxers) versus nonscreened (French and English Bulldogs German Shepherds), investigated association with CHDs, determined popularity volatility 20-year period; analysed trends most popular overall new-born registered Italian Kennel Club from 1st January...
Specific microRNAs expressions may accurately characterize different stages of canine myxomatous mitral valve disease. This preliminary pilot study aimed to (1) describe the clinical and echocardiographic parameters Cavalier King Charles Spaniels affected by disease at American College Veterinary Internal Medicine (ACVIM) (B1, B2 C) healthy control group (ACVIM A), comparing collected during first examination (T0) end follow-up (T1); (2) assess association between values T1 expression...
Persistent right aortic arch (PRAA) in cats is an uncommon vascular anomaly with clinical signs referable to oesophageal obstruction. To our knowledge no reports of axial skeletal malformations concomitant PRAA have been reported cats. The aim this study depict a new feature affected by PRAA. In the six diagnosis ring were enrolled. A complete physical examination, neurological examination and total body radiograph performed on each animal. Four showed contemporary malformations....
Abstract Standard transthoracic echocardiography is considered the non-invasive gold standard for diagnosis of most cardiac diseases. Defining reproducibility, repeatability, and reliability this exam imperative to reduce errors in clinical evaluations. The present study aimed at: (1) evaluating reproducibility repeatability 15 echocardiographic parameters dogs by analyzing measurements obtained from several operators with different levels experience comparing them ones two board-certified...
Paratuberculosis or Johne’s disease in cattle is a chronic granulomatous gastroenteritis caused by infection with Mycobacterium avium subspecies paratuberculosis (MAP). not treatable; therefore, the early identification and isolation of infected animals key point to reduce its incidence. In this paper, we analyse RNAseq experimental data 5 ELISA-negative exposed MAP positive herd, compared negative-unexposed controls. The purpose was find small set differentially expressed genes able...
A mutation in the canine multidrug resistance MDR1 gene (also referred as ABCB1), encoding for (MDR) P-glycoprotein (P-gp) transponder, causes a pathological condition known 'ivermectin toxicosis'. The causative mutation, since 2001, has been described to affects sheep herding breeds related collie lineage. present study is retrospective investigation of presence mutated allele Italian dog populations 5 years' time lapse. aim research offer deep knowledge allelic and genotypic frequencies...