This study describes the echocardiographic reference intervals in a large sample of Golden retrievers from database Italian Veterinary Observatory for Cardiac Diseases. The variables and cardiac functionality indexes obtained 2012 to 2022 214 (122 females, 92 males) healthy adult were compared with previously published data this breed general canine population other breeds. diastolic left ventricular internal diameter ventricle's systolic allometric indices higher than those reported...

ABSTRACT Background Bronchopneumonia (BP) can cause pulmonary hypertension (PH) and secondary cardiovascular changes. Objectives The aim of this study was to describe PH–related transthoracic Doppler echocardiography (TTE) changes in preweaned dairy calves with BP diagnosed by thoracic ultrasonography (TUS). Animals One hundred sixty‐four were selected from 11 commercial farms. Methods This is a case–control study. enrolled grouped according TUS results into either the control group (with...

Abstract Cavalier King Charles Spaniels (CKCS) are predisposed to developing myxomatous mitral valve disease (MMVD), with radiographs frequently used screen for evidence of left‐sided cardiomegaly secondary MMVD. Vertebral heart size (VHS), vertebral left atrial (VLAS), modified VLAS (M‐VLAS), and radiographic dimension (RLAD) reported as objective measurements global size. Normal VHS in CKCS (10.6 ± 0.5) is reportedly higher than the non‐breed‐specific value (9.7±0.5). Breed‐specific VLAS,...

There is a growing interest in developing new molecular markers of heart disease young dogs affected by myxomatous mitral valve disease. The study aimed to measure 3 circulating microRNAs and their application as potential biomarkers the plasma Cavalier King Charles Spaniels with early asymptomatic hypothesis that healthy have different microRNA expression profiles than American College Veterinary Internal Medicine (ACVIM) stage B1. can differ within same class among subjects ages. This...

Taurine deficiency predisposes to the development of nutritional dilated cardiomyopathy and is widespread in dogs fed with non-traditional diets. However, Golden retrievers show lower plasma taurine concentration an impaired systolic function compared breeds same size morphotype. For these reasons, it can be difficult classify a subject from cardiological point view, risk considering as pathological characteristics that completely normal this breed. This cross-sectional multicenter study....

Specific microRNAs expressions may accurately characterize different stages of canine myxomatous mitral valve disease. This preliminary pilot study aimed to (1) describe the clinical and echocardiographic parameters Cavalier King Charles Spaniels affected by disease at American College Veterinary Internal Medicine (ACVIM) (B1, B2 C) healthy control group (ACVIM A), comparing collected during first examination (T0) end follow-up (T1); (2) assess association between values T1 expression...

Abstract Standard transthoracic echocardiography is considered the non-invasive gold standard for diagnosis of most cardiac diseases. Defining reproducibility, repeatability, and reliability this exam imperative to reduce errors in clinical evaluations. The present study aimed at: (1) evaluating reproducibility repeatability 15 echocardiographic parameters dogs by analyzing measurements obtained from several operators with different levels experience comparing them ones two board-certified...

Introduction Arterial blood gas analysis is the gold standard for assessment of oxygenation, ventilation, and metabolic status in dogs; however, its execution difficult painful. Therefore, venous used replacement status, but it not clear whether can be to assess respiratory function, too. This study aimed at: 1) comparing jugular saphenous pH partial pressure carbon dioxide (pCO 2 ) with correspondent arterial pCO (paCO healthy dogs during general anesthesia; 2) clarifying arterial-venous...

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main source(s): Transnational Research Projects on Cardiovascular Diseases Background Arrhythmogenic Cardiomyopathy (ACM) is an inherited heart disorder characterized by a high incidence sudden death at young age. Mutations linked to ACM occur primarily in desmosomal genes (e.g. PKP2) [1]. Different cell types individually contribute set the phenotype with either functional abnormalities (cardiomyocytes;...

Canine degenerative myelopathy is a fatal neurodegenerative disorder that affects the spinal cord. It late-onset disease, with symptoms becoming evident later in life at approximately 8 years of age. The principal aim this study was to retrospectively evaluate allelic and genotypic frequencies c.118G > A c.52A T mutations located on SOD1 gene an Italian canine population provide detailed information prevalence country. genetic data different breeds were collected through DNA tests over...

Objectives The aims of this study were to compare the sedative effect, feasibility venous angiocatheter placement and influence on heart rate (HR), systemic blood pressure (SBP) echocardiographic variables two multimodal anaesthetic protocols in uncooperative cats; their HR, SBP 20 mins after sedation elective ovariectomy. Methods Eighteen stray female cats randomly received intramuscular (IM) ketamine (2 mg/kg) methadone (0.3 plus dexmedetomidine (7 µg/kg; group D, n = 9) or alfaxalone...

To evaluate if the functional grading system (Cambridge classification) of brachycephalic obstructive airways syndrome (BOAS) and temperament score can be useful tools in predicting feasibility echocardiographic examination lateral recumbency. The hypothesis is that dog, rather than severity BOAS alone, exacerbate respiratory symptoms (dyspnea, stertor, stridor and/or cyanosis) during containment.

Abstract Echocardiography is the most widely accepted diagnostic tool for assessment of cardiac function and morphology in dogs usually performed lateral recumbency. However, some situations or stressed patients, it necessary to perform a standing position. Only one study evaluated effects animal position on selected two‐dimensional M‐mode echocardiographic variables four healthy different breeds, but not brachycephalic breeds. In these breeds evaluation sometimes needed due severity...

Dilated cardiomyopathy (DCM) is the most common myocardial disorder in dogs, and it primarily considered to be an inherited or genetic disease with a higher prevalence specific breeds such as Doberman Pinschers Great Danes. Recently, several publications have reported concerns about cases of DCM unusual (Golden Retrievers-GRs) associated them diets (grain-free, high pulses potatoes, low taurine amino acid precursors). Because involved digestion absorption fat liposoluble vitamins, including...

The development and progression of myxomatous mitral valve disease (MMVD) in Cavalier King Charles Spaniels (CKCS) are difficult to predict. Thus, the identification dogs with a morphotype associated more severe at young age is desirable. aims this study were to: (1) describe physical, morphometric, echocardiographic features class B1 MMVD-affected according American College Veterinary Internal Medicine (ACVIM) guidelines; (2) evaluate influence morphometric physical measurements on murmur...

Abstract There is a growing interest in developing new molecular markers of heart disease young Cavalier King Charles Spaniels affected by myxomatous mitral valve disease. The aim the study was to measure abundance 3 circulating microRNAs and their application as potential biomarkers plasma with early asymptomatic 33 dogs American College Veterinary Internal Medicine (ACVIM) stage B1 were divided three groups (11 younger than years, 11 older years 7 years), healthy (ACVIM A) included control...

Abstract Standard transthoracic echocardiography is considered the non-invasive gold standard for diagnosis of most cardiac diseases. Defining reproducibility, repeatability, and reliability this exam imperative to reduce errors in clinical evaluations. The present study aimed at: 1) evaluating reproducibility repeatability 15 echocardiographic parameters dogs by analyzing measurements obtained from several operators with different levels experience comparing them ones two board-certified...

Progressive retinal atrophy (PRA) is a group of canine inherited disorders affecting up to 100 breeds. Genetic tests are available. The aim this study was retrospectively evaluate the genetic variants associated with PRA among dogs residing in Italy.Genetic data 20 different forms were collected through DNA over 10-year period for several dog breeds Italian population. Allelic and genotypic frequencies calculated.A total 1467 conducted 1180 dogs. rod-cone degeneration (PRCD) most tested form...

Abstract Specific microRNAs expressions may accurately characterize different stages of canine myxomatous mitral valve disease. This preliminary study aimed to (1) describe the clinical and echocardiographic parameters Cavalier King Charles Spaniels affected by disease at American College Veterinary Internal Medicine (ACVIM) (B1, B2 C) healthy control group (ACVIM A), comparing collected during first examination (T0) end follow-up (T1); (2) assess association between values T1 expression...

Abstract Development and progression of myxomatous mitral valve disease (MMVD) in Cavalier King Charles Spaniels (CKCS) are difficult to predict. Identification at a young age dogs with morphotype associated more severe is desirable. The aims this study were to: 1) describe the physical, morphometric, echocardiographic features MMVD affected American College Veterinary Internal Medicine (ACVIM) class B1; 2) evaluate influence morphometric physical measurements on murmur intensity, prolapse...