In this study, we investigated the efficacy of patient-controlled regional analgesia for outpatients undergoing moderately painful orthopedic surgery shoulder. Preoperatively, patients (n = 20) received an interscalene nerve block and perineural catheter. Postoperatively, were discharged home with both oral opioids a portable infusion pump delivering either 0.2% ropivacaine or 0.9% saline, determined randomly in double-blinded manner. Daily end points included pain scores, opioid use side...

Background This randomized, double-blinded, placebo-controlled study investigated the efficacy of patient-controlled regional analgesia using a sciatic perineural catheter in popliteal fossa and portable infusion pump for outpatients having moderately painful, lower extremity orthopedic surgery. Methods Preoperatively, patients (n = 30) received nerve block fossa. Postoperatively, were discharged with both oral opioids delivering solution (0.2% ropivacaine or 0.9% saline) via 3 days....

Background This randomized, double-blinded, placebo-controlled study investigated the efficacy of patient-controlled regional analgesia using an infraclavicular brachial plexus perineural catheter and a portable infusion pump for outpatients undergoing moderately painful, upper extremity orthopedic surgery. Methods Preoperatively, patients (n = 30) received nerve block catheter. Postoperatively, were discharged home with oral narcotics delivering solution (0.2% ropivacaine or 0.9% saline)...

Abstract Objective —To compare 3 types of noxious stimuli applied to various anatomic areas anesthetized dogs and rabbits for determination the minimum alveolar concentration (MAC). Animals —10 10 rabbits. Procedure —Dogs were with isoflurane halothane in a randomized order. Rabbits isoflurane. The MAC was determined by skin incision on lateral aspect chest; clamping tail, paw forelimb, hind limb; application electrical current oral mucosa (dogs only), limb. end-tidal midway between value...

ZnO nanorod-gated AlGaN∕GaN high electron mobility transistors (HEMTs) are demonstrated for the detection of glucose. A nanorod array was selectively grown on gate area using low temperature hydrothermal decomposition to immobilize glucose oxidase (GOx). The one-dimensional nanorods provide a large effective surface with surface-to-volume ratio and favorable environment immobilization GOx. HEMT drain-source current showed rapid response less than 5s when target in buffer pH value 7.4 added...

BACKGROUND: Sellick described cricoid pressure (CP) as pinching the esophagus between ring and cervical spine. A recent report noted that with application of CP, moved laterally more than 90% time, questioning efficacy this maneuver. We designed study to accurately define anatomy maneuver investigate its efficacy. METHODS: Twenty-four nonsedated adult volunteers underwent neck magnetic resonance imaging without CP. Measurements were made postcricoid hypopharynx, airway compression, lateral...

We have proposed a novel hypothesis regarding the potential role of occupational or second-hand exposure in physician substance use, abuse, and addiction. While only 5.6% licensed physicians Florida are anesthesiologists, nearly 25% followed for abuse/dependence anesthesiologists. When we sort by drug choice, anesthesiologists more opioid abuse dependence than other appropriate controls. Abuse one opioid, fentanyl, appears to be increasing has been noted among State Florida's causes deaths....

Background In this randomized, double-blind study, the authors investigated efficacy of continuous and patient-controlled ropivacaine infusions via an infraclavicular perineural catheter in ambulatory patients undergoing moderately painful orthopedic surgery at or distal to elbow. Methods Preoperatively, (n = 30) received nerve block. Postoperatively, were discharged home with both oral analgesics a portable infusion pump delivering 0.2% (500-ml reservoir) one three dosing regimens: basal...

<h3>Objective</h3> To determine if preemptive analgesia with ropivacaine hydrochloride or without clonidine decreases pain and hastens recovery after tonsillectomy. <h3>Design</h3> Prospective, randomized, triple-blinded trial. <h3>Setting</h3> University referral center; pediatric ambulatory practice. <h3>Participants</h3> Sixty-four children, aged 3 to 15 years, undergoing <h3>Interventions</h3> Patients received injections in the tonsillar fossae of isotonic sodium chloride, ropivacaine,...

We hypothesized that custom-designed microemulsions would effectively scavenge compounds from bulk media. Pluronic-based oil-in-water were synthesized efficiently reduced the free concentration of local anesthetic bupivacaine in 0.9% NaCl. Both molecular nature and constituents significantly affected extraction efficiencies. Pluronic F127-based extracted more than using other surfactants (L44, L62, L64, F77, F87, F88, P104). Extraction was markedly increased by addition fatty acid sodium...

<h3>Objective:</h3> Documented falls after lower-extremity-nerve blocks are rare. We believe this paucity of documented is the result underreporting and lack serious complications resulting from these falls. In addition, mechanism(s) for has not been elucidated. <h3>Case Reports:</h3> These reports highlight mechanism fall in a patient with femoral-nerve block (FNB) sciatic-nerve (FNB/SNB). we report our findings when volunteers underwent FNB, (SNB) FNB/SNB were studied gait-analysis...

On January 12, 2010, a 7.0 M(L) earthquake devastated Haiti, the most impoverished nation in Western hemisphere with extremely limited health care resources. We traveled to Milot, Haiti situated north of Port-au-Prince, for injured patients at Hôpital Sacré Coeur, an undamaged hospital 74 beds and 2 operating rooms. The massive influx brought by helicopter from zone transformed >400 6 As 2005 Kashmir 2008 China earthquake, victims suffered extremity injuries, encompassing crush lacerations,...

<h3>Background and Objectives</h3> Although a continuous interscalene nerve block (CISB) has been shown to provide potent analgesia after major shoulder surgery, its potential effects on postoperative rehabilitation remain uninvestigated. Therefore, this retrospective case-control study was undertaken determine the association between CISB joint range-of-motion total arthroplasty (TSA). <h3>Methods</h3> The medical records for patients who underwent TSA at our institution in previous 3 years...

This randomized, double-blind study investigated the efficacy of continuous and patient-controlled ropivacaine infusion via a popliteal sciatic perineural catheter in ambulatory patients undergoing moderately painful orthopedic surgery foot or ankle.Preoperatively, (n = 30) received posterior nerve block. Postoperatively, were discharged home with portable pump delivering 0.2% (500 ml) one three dosing regimens: basal group (12-ml/h rate, 0.05-ml bolus dose), basal-bolus (8-ml/h 4-ml...

Portable pumps used for local anesthetic infusion during continuous regional analgesia are gaining acceptance. These often ambulatory patients who medically unsupervised throughout most of the infusion. However, performance these pumps, which infuse potentially toxic medication, has not been independently investigated. We investigated flow rate accuracy, consistency, and profiles various portable analgesia. By using a computer/scale combination within laboratory to record rates, 6 were...

Although clonidine has been shown to increase the duration of local anesthetic action and prolong postoperative analgesia when included in single-injection nerve blocks, a controlled investigation efficacy this practice improve for continuous perineural infusion not reported. In study, ambulatory patients (n = 34) undergoing moderately painful upper extremity orthopedic surgery received an infraclavicular brachial plexus block (mepivacaine 1.5%, epinephrine 2.5 micro g/mL, bicarbonate 0.1...

Sevoflurane administered to neonatal rats induces neurobehavioral abnormalities and epigenetic reprogramming of their germ cells; the latter can pass adverse effects sevoflurane future offspring. As cells are susceptible by environmental factors across lifespan, authors hypothesized that adult could induce in offspring, but not exposed themselves.Sprague-Dawley were anesthetized with 2.1% for 3 h every other day between postnatal days 56 60. Twenty-five later, nonexposed controls mated...