A5071649447- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Infection Control and Ventilation
- Retinoids in leukemia and cellular processes
- Pharmacological Receptor Mechanisms and Effects
- Immune responses and vaccinations
- Pediatric health and respiratory diseases
- interferon and immune responses
- COVID-19 diagnosis using AI
- Receptor Mechanisms and Signaling
- Long-Term Effects of COVID-19
- Hepatitis B Virus Studies
- Respiratory viral infections research
- HIV-related health complications and treatments
- COVID-19 epidemiological studies
- Vitamin D Research Studies
- Thermal Regulation in Medicine
- Computational Drug Discovery Methods
- Inhalation and Respiratory Drug Delivery
- Neuroinflammation and Neurodegeneration Mechanisms
- HIV Research and Treatment
- Malaria Research and Control
Rutgers, The State University of New Jersey
2025
University of Southern California
2022-2024
Southern California University for Professional Studies
2024
Retinitis pigmentosa (RP) is a retinal degenerative disease associated with diversity of genetic mutations. In natural progression study (NPS) evaluating the molecular changes in Royal College Surgeons (RCS) rats using lipidomic profiling, RNA sequencing, and gene expression analyses, degeneration from p21 to p60 were evaluated, where reductions ALOX15 corresponded progression. This important enzyme catalyzes formation specialized pro-resolving mediators (SPMs) such as lipoxins (LXs),...
Despite the strides made in recent decades, resistance observed existing antimalarial drugs, and intricate life cycle of Plasmodium parasite underscore pressing need to develop novel effective therapeutic interventions. This article provides a comprehensive evaluation outcomes stemming from screening library comprising 48 compounds (TCAMS) against falciparum. study focused on characterizing IC50 values Tres Cantos Antimalarial Set via double-labelling method P. falciparum parasites with SYBR...
The emergence and mutation of pathogenic viruses have been occurring at an unprecedented rate in recent decades. coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome 2 (SARS-CoV-2) has developed into a global public health crisis due to extensive viral transmission. In situ RNA mapping revealed angiotensin-converting enzyme (ACE2) expression be highest the nose lower lung, pointing nasal susceptibility as predominant route for infection cause subsequent...
Abstract Airborne transmission by droplets and aerosols is known to play a critical role in the spread of many viruses amongst which are common flu more recent SARS-CoV-2 viruses. In case SARS-CoV-2, nasal cavity not only constitutes an important viral entry point, but also primary site infection (Sungnak W. et al. Nat. Med. 26:681–687. https://doi.org/10.1038/s41591-020-0868-6 , 2020).. Although face masks well-established preventive measure, development novel easy-to-use prophylactic...
OBJECTIVES/GOALS: Susceptible mucocutaneous membranes of the eye and nasal cavity are easily infected by viruses leading to pink or respiratory infections whose direct cost has been estimated as $16 billion annually in United States. We have developed a novel effective barrier that will be agnostic variants enveloped like coronaviruses. METHODS/STUDY POPULATION: evaluated efficacy hydroxypropyl cyclodextrin preventing coronavirus using 25 humanized angiotensin converting enzyme-2 receptor...
Chronic HIV infection has long been associated with an increased risk for cardiovascular diseases. The metabolites of the renin−angiotensin system (RAS) such as angiotensin II (AngII) play important role in regulating blood pressure and fluid dynamics. Cross-sectional analysis HIV-positive individuals (n = 71, age > 40 years, stable ART 3 months viral load < 50 copies/mL) were compared to a similar seronegative group 72). High-resolution B-mode ultrasound images right carotid bifurcation...
More than any other infectious disease epidemic, the COVID-19 pandemic has been characterized by generation of large volumes viral genomic data at an incredible pace due to recent advances in high-throughput sequencing technologies, rapid global spread SARS-CoV-2, and its persistent threat public health. However, distinguishing most epidemiologically relevant information encoded these vast amounts requires substantial effort across research health communities. Studies SARS-CoV-2 genomes have...