A5000850477- Electrospun Nanofibers in Biomedical Applications
- Essential Oils and Antimicrobial Activity
- Advancements in Transdermal Drug Delivery
- Electrohydrodynamics and Fluid Dynamics
- Nanoparticle-Based Drug Delivery
- Bee Products Chemical Analysis
- Occupational Health and Safety Research
- Advanced Sensor and Energy Harvesting Materials
- Insect Pest Control Strategies
- Quality and Safety in Healthcare
- Neurobiology and Insect Physiology Research
- Antimicrobial agents and applications
- Curcumin's Biomedical Applications
- Toxoplasma gondii Research Studies
- Nicotinic Acetylcholine Receptors Study
- Biochemical effects in animals
- Conducting polymers and applications
- Neuroscience and Neuropharmacology Research
- Polymer Surface Interaction Studies
- Aquatic life and conservation
- Escherichia coli research studies
- Bioinformatics and Genomic Networks
- Advanced Biosensing Techniques and Applications
- Biosensors and Analytical Detection
- Oral and Craniofacial Lesions
Tehran University of Medical Sciences
2016-2025
Klinik für Herzchirurgie Karlsruhe
2024
Isfahan University of Medical Sciences
2015-2024
University of Isfahan
2023
Institute for Advanced Studies in Basic Sciences
2023
Agricultural Research & Education Organization
2017-2022
Tabriz University of Medical Sciences
2019
Agricultural Biotechnology Research Institute of Iran
2017
Arak University of Medical Sciences
2015
Qom University of Medical Science and Health Services
2015
Eugenol is the main constituent of clove oil with anti-inflammatory properties. In this work, for first time, O/W nanoemulsion eugenol was designed evaluation effects as a topical delivery system. Topical formulations containing 1%, 2% and 4% well system 0.5% piroxicam were prepared. Further to physicochemical examinations, such determination particle size, polydispersity index, zeta potential physical stability, activity examined in carrageenan-induced paw edema rats. The optimum...
Natural polysaccharides such as chitosan (CS) are widely used antimicrobial agents. In recent years, and considering that CS has a strong potential, interest been focused on activity of nanoparticles (CS NPs). The main factors affecting the antibacterial include molecular weight (MW) concentration. this regard, aim study was to produce various MWs concentrations NPs, through ionic gelation method, investigate their potential anti-parasitic against tachyzoites Toxoplasma gondii RH strain.The...
Background: The aim of this study was to prepare curcumin nanoemulsion (CR-NE) solve the problems associated with poor water solubility and low bioavailability CR test its efficiency in treatment acute chronic toxoplasmosis mouse models. Materials methods: CR-NE 1% prepared using spontaneous emulsification by soybean as oil phase; a mixture Tween 80 85 surfactant; ethanol cosurfactant distilled water. Particle size zeta potential NE were assessed Nano-ZS90 dynamic light scattering. Stability...
Cinnamon (Cinnamomum zeylanicum) and Clove (Syzygium aromaticum) essential oils are two medicinally important plant-derived substances with a wide range of biological properties. Besides, nanoemulsion-based gels have been widely used to increase topical drug delivery effectiveness.
Background: In this study, larvicidal activity of clove essential oil (EO), as a green and relatively potent larvicide, was compared with its main constituent, Eugenol, against Anopheles stephensi. Methods: High-performance liquid chromatography (HPLC) used to determine the amount eugenol, major constituent EO. addition, EO eugenol evaluated An. Results: The in determined 67% using HPLC analysis. LC50 LC90 (57.49 93.14ppm, respectively) were significantly lower than those (86.96 128.18 ppm,...
Background Acanthamoeba keratitis (AK) is a corneal sight-threatening infection caused by the free-living amoebae of genus . Early and appropriate treatment significantly impacts visual outcomes. Mucoadhesive polymers such as chitosan are potential strategy to prolong residence time bioavailability encapsulated drugs in cornea. Regarding recent administration miltefosine (MF) for treating resistant AK, present study, we synthesized miltefosine-loaded nanoparticles (MF-CS-NPs) evaluated them...
Recently, the anti-tumor effects of cannabis extract on various cancers have attracted attention researchers. Here, we report a nanoemulsion (NE) composition designed to enhance delivery two active components in extracts (∆9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD)) an animal model glioblastoma. The efficacy NE containing drugs (NED) was compared with bulk carrier (NE without drugs) using C6 tumor rats. Hemocompatibility factors (RBC, MCV, MCH, MCHC, RDW, PPP, PT PTT) were studied...
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. Engineered biomolecules can be used as a targeted tool to deliver drugs directly tumors that reduce adverse effects conventional treatments. We aimed prepare non-targeted oxaliplatin-loaded chitosan nanoparticles (OXPT-CS NPs) and OXPT-CS NPs decorated with cetuximab single-chain variable fragment (scFv) send both epidermal growth factor receptor (EGFR) overexpressing HCT 116 cells, human colorectal...
This study investigated the effects of dietary mixed and sprayed Bacillus subtilis subsp. inaquosorum IS02 (B.s.i. IS02) on growth performance digestive enzyme activity whiteleg shrimp. Three different dosages B.s.i. were applied via two application methods: with (TM) (TS) feed containing 108 (TM1 TS1), 107 (TM2 TS2), 106 (TM3 TS3) CFU Kg−1. Compared to control groups, was significantly higher in treated There a significant difference survival rate between TM1 (94.44 ± 1.57%) TM2 (87.78...
Nanoemulsion has shown many advantages in drug delivery systems. In this study, for the first time, analgesic and anti-inflammatory properties of a nanomelusion almond oil with without ibuprofen was compared corresponding microemulsion commercial topical gel using formalin carrageenan tests, respectively.Almond (oil phase) mixed Tween 80 Span (surfactants), ethanol (co-surfactant) them distilled water (aqueous then added to mixture at once. Prepared nanoemulsions were pre-emulsified into 100...
A rapid and efficient procedure for DNA transformation is a key prerequisite successful cloning genomic studies. While there are efforts to develop facile method, so far obtained efficiencies alternative methods have been unsatisfactory (i.e. 105–106 CFU/μg plasmid) compared with conventional method (up 108 plasmid). In this work, the first time, we prepared chitosan/pDNA nanoparticles by electrospraying improve process. Electrospray was used production investigate non-competent bacterial...
Objective(s): Among herbal oils, cinnamon bark oil has several advantages such as anti-inflammatory and antimicrobial activity. It is already reported that particle size of droplets affects their properties antibacterial In this study, we investigated inhibitory activity products including bulk, microemulsion (ME) nanoemulsion (NE). Methods: ME NE were prepared by low energy methods. Physicochemical characterization ME (COME) (CONE) investigated. Bulk, evaluated for against Escherichia...
Background: Colorectal cancer [CRC] is among the most fatal types of cancer. An active targeting delivery system that specifically interacts with CRC cells could improve therapy's outcomes. Herein, Cetuximab single-chain fragment variable antibody [scFv] fragments were conjugated to surface 5-FU encapsulated chitosan nanoparticles [CS NPs] develop an effective therapeutic platform [scFv-CS/5-FU NPs]. Method: CS/5-FU NPs synthesized using a special fluidic system. Encapsulation efficiency...