Ying-Kai Xu

ORCID: 0000-0003-2945-2724
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About
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Research Areas
  • Cardiovascular Function and Risk Factors
  • Acute Myocardial Infarction Research
  • Lipoproteins and Cardiovascular Health
  • Coronary Interventions and Diagnostics
  • Cardiac Imaging and Diagnostics
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cancer, Lipids, and Metabolism
  • Vascular Procedures and Complications
  • Cardiac and Coronary Surgery Techniques
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Congenital Heart Disease Studies
  • Cardiovascular Issues in Pregnancy
  • Atherosclerosis and Cardiovascular Diseases
  • COVID-19 Clinical Research Studies
  • Cardiac Valve Diseases and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Cerebrovascular and Carotid Artery Diseases
  • SARS-CoV-2 detection and testing
  • Diabetes Management and Research
  • Frailty in Older Adults
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Renal and Vascular Pathologies
  • Cardiovascular Health and Disease Prevention
  • Nutrition and Health in Aging
  • Lipid metabolism and disorders

Capital Medical University
2020-2025

General Hospital of Central Theater Command
2024

Wuhan University of Science and Technology
2024

Central Hospital of Wuhan
2024

Beijing Anzhen Hospital
2020-2022

Abstract Background The relationship between triglyceride-glucose index (TyG index) and the prevalence prognosis of cardiovascular disease has been confirmed by former studies. However, it remains uncertain whether TyG a prognostic impact in patients with type 2 diabetes mellitus (T2DM) non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing percutaneous intervention (PCI). Methods study retrospectively enrolled 798 (mean age: 60.9 ± 8.3 years; 68.3% men) T2DM NSTE-ACS who...

10.1186/s12933-020-01086-5 article EN cc-by Cardiovascular Diabetology 2020-07-08

Abstract Background Many studies have reported the predictive value of atherogenic index plasma (AIP) in progression atherosclerosis and prognosis percutaneous coronary intervention (PCI). However, utility AIP for prediction is unknown after PCI among type 2 diabetes mellitus (T2DM). Methods 2356 patients with T2DM who underwent were enrolled followed up 4 years. The primary outcome was major cardiovascular cerebrovascular adverse events (MACCEs), considered to be a combination cardiogenic...

10.1186/s12933-020-0989-8 article EN cc-by Cardiovascular Diabetology 2020-02-21

The triglyceride-glucose index (TyG index) is proposed as a surrogate parameter for insulin resistance (IR) and, when elevated, related to increased cardiovascular risks. Whether the TyG of great value in predicting adverse prognosis individuals diagnosed with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), who received elective percutaneous intervention (PCI), and without recognized diabetes remains unclear.

10.5551/jat.59840 article EN Journal of Atherosclerosis and Thrombosis 2020-11-12

Insulin resistance (IR), evaluation of which is difficult and complex, closely associated with cardiovascular disease. Recently, various IR surrogates have been proposed proved to be highly correlated assessed by the gold standard. It remains indistinct whether different perform equivalently on prognostic prediction stratification following percutaneous coronary intervention (PCI) in non-ST-segment elevation acute syndrome (NSTE-ACS) patients without type 2 diabetes mellitus (T2DM).

10.1186/s12933-021-01383-7 article EN cc-by Cardiovascular Diabetology 2021-09-18

In recent years, novel cardiometabolic biomarkers and related pathogenic genes their heritability have been examined. However, no multitarget predictive evaluation models exist can identify predict complex lesions in unstable angina (UA) the early stages before coronary angiography (CAG) or evaluate prognosis of patients with UA lesions. this study, we sought to investigate correlation between blood lipid, glucose, inflammatory indices occurrence lesions, also risk factors for major adverse...

10.21037/jtd-2024-2122 article EN Journal of Thoracic Disease 2025-01-01

Abstract Background It is uncertain whether estimated remnant-like particle cholesterol (RLP-C) could predict residual risk in patients with different glycometabolic status. This study aimed to evaluate the relationship between RLP-C and adverse prognosis non-ST-segment elevation acute coronary syndrome (NSTE-ACS) treated percutaneous intervention (PCI) identify potential impact of glycometabolism on predictive value RLP-C. Methods The assessed 2419 participants NSTE-ACS undergoing PCI at...

10.1186/s12944-020-01355-y article EN cc-by Lipids in Health and Disease 2020-07-31

Background: The research on the association between relative glycemic level postpercutaneous coronary intervention (PCI) and adverse prognosis in non-ST-segment elevation acute syndrome (NSTE-ACS) patients is relatively inadequate. Objective: study aimed to identify whether post-PCI predicts NSTE-ACS patients. Methods: Patients (n=2465) admitted with who underwent PCI were enrolled. post-procedure was calculated as blood glucose divided by HbA1c level, which named post-procedural index...

10.2174/1570161118666200317145540 article EN Current Vascular Pharmacology 2020-03-17

Triglyceride-glucose (TyG) index, a novel surrogate marker of insulin resistance, has been demonstrated to be significantly associated with cardiovascular disease. It remains indistinct regarding the association between TyG index and non-culprit coronary plaque characteristics in patients following acute syndrome (ACS). The present study retrospectively recruited who were diagnosed ACS underwent optical coherence tomography (OCT) examination. population was divided into 2 groups based on...

10.3389/fcvm.2022.1019233 article EN cc-by Frontiers in Cardiovascular Medicine 2022-10-12

Visceral adiposity index (VAI), a surrogate marker of and insulin resistance, has been demonstrated to be significantly related cardiovascular disease. It remains indistinct whether VAI predicts adverse prognosis after percutaneous coronary intervention (PCI) for patients with non-ST-segment elevation acute syndrome (NSTE-ACS) type 2 diabetes mellitus (T2DM).

10.3389/fcvm.2021.735637 article EN cc-by Frontiers in Cardiovascular Medicine 2021-11-18

Background Azvudine, a repurposed oral small molecule antiviral drug, has potential effects in combating the SARS-CoV-2 virus. However, studies on its clinical efficacy patients with COVID-19 are still limited and controversial, further research validation necessary. Methods A retrospective cohort study was conducted who were hospitalized General Hospital of Central Theater Command from 1 December 2022 to 31 January 2023. We included 132 treated Azvudine controls after screening propensity...

10.3389/fcimb.2024.1453234 article EN cc-by Frontiers in Cellular and Infection Microbiology 2024-11-07

Abstract Background To compare the surgical effects of coronary intervention through transradial (TRI) versus distal (dTRI) approach. Methods From September 2020 to April 2021, 302 patients undergoing artery angiography (CAG) or percutaneous in our hospital were retrospectively included. Patients divided into TRI group and dTRI with 151 cases each group. The technique features, lesion cannulation process compared between two groups. Results number who underwent CAG (35.1%) was significantly...

10.1186/s13019-022-01979-4 article EN cc-by Journal of Cardiothoracic Surgery 2022-09-07

Objectives To compare the effectiveness and safety of Braidin® slender 7 Fr sheath with a standard 6 for treating left main bifurcation disease. Methods From January 2017 to March 2019, 277 patients disease who underwent transradial approach percutaneous coronary intervention were divided into group (Braidin® sheath, n = 154) (n 123). Pathological features, surgical effect, complications evaluated. Results The rate using classic crush technique was significantly higher in than group. had...

10.1177/0300060520954727 article EN cc-by-nc Journal of International Medical Research 2020-09-01

Objectives: Coronary artery bypass grafting (CABG) success is reduced by graft occlusion. Understanding factors associated with occlusion may improve patient outcomes. The aim of this study was to develop a predictive risk score for saphenous vein (SVG) after CABG. Methods: This retrospective cohort enrolled 3,716 CABG patients from January 2012 March 2013. development included 2,477 and the validation 1,239 patients. baseline clinical data at index analyzed their independent impact on in...

10.3389/fcvm.2021.670045 article EN cc-by Frontiers in Cardiovascular Medicine 2021-08-12

Two theories have been implied in the pathogenesis of coarctation aorta (CoA), i.e. diminished flow and ductal tissue growth juxtaductal area. We sought to investigate fetal by 3D/4D echocardiography (FE) computational fluid dynamics (CFD) understand cause improve diagnosis prognosis CoA. Computational model aortic arches was built FE Doppler from normal fetus. Pulsatile hemodynamics, including velocity, pressure gradient, wall shear stress, were stimulated as decreased 100% 80%, 60%, 40%,...

10.1002/uog.22549 article EN Ultrasound in Obstetrics and Gynecology 2020-10-01

To explore the clinical effect and radial remodeling of transradial slender 7 Fr sheath for left main bifurcation disease (LM bifurcation).From January 2018 to September 2019, 236 patients with LM undergoing percutaneous coronary intervention (PCI) from two heart centers were divided into group (n = 127) 6 109). Quantitative angiography (QCA) very high-frequency ultrasound/ultra biomicroscopy (VHFUBM) used assess sheath.Slender had a higher preoperative distal angle (67.271 ± 22.886) than...

10.1080/03007995.2020.1815684 article EN Current Medical Research and Opinion 2020-08-27

Abstract Background: Coronary artery bypass grafting (CABG) success is reduced by graft occlusion. Patients with type 2 diabetes mellitus(T2DM) are more likely to develop Understanding factors associated occlusion may improve T2DM patient outcomes. The aim of this study was a predictive risk score for saphenous vein (SVG) in patients after CABG.Methods: This retrospective cohort enrolled 3716 CABG from January 2012 March 2013. development included 2477 and the validation 1239 patients....

10.21203/rs.3.rs-63447/v1 preprint EN cc-by Research Square (Research Square) 2020-11-19

Abstract Background The relationship between triglycerides-glucose index (TyG index) and the prevalence prognosis of cardiovascular disease has been confirmed by former studies. However, it remains uncertain whether TyG a prognostic impact in patients with type 2 diabetes mellitus (T2DM) non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing percutaneous intervention (PCI). Methods study retrospectively enrolled 832 (mean age: 60.7 ± 8.4 years; 68.1% men) T2DM NSTE-ACS who...

10.21203/rs.3.rs-28546/v1 preprint EN cc-by Research Square (Research Square) 2020-05-20

Retrograde flow (RF) in the aortic isthmus is frequently observed fetuses various hemodynamic states including congenital heart defects (CHD). This study sought to: establish association between this observation and variables of CHD by fetal echocardiography (FE); to develop a CFD model probe causes mechanisms underlying observation. A total 256 (gestational age (GA) 26.3 ± 9.8 weeks) with 1,168 normal ones (GA: 25.8 10.3 were examined FE from January, 2011 May, 2016. The group was divided...

10.1002/uog.22554 article EN Ultrasound in Obstetrics and Gynecology 2020-10-01

Abstract Background: It is uncertain whether remnant-like particle cholesterol (RLP-C) could predict residual risk in patients under different glucose metabolic status. This study aimed to evaluate the relationship between RLP-C and adverse prognosis with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing percutaneous intervention (PCI) identify potential impact of metabolism on predictive value RLP-C. Methods: The enrolled 2419 NSTE-ACS who underwent PCI at Beijing...

10.21203/rs.3.rs-37986/v1 preprint EN cc-by Research Square (Research Square) 2020-06-29

Abstract Background: It is uncertain whether remnant-like particle cholesterol (RLP-C) could predict residual risk in patients under different glucose metabolic status. The study aimed to evaluate the relationship between RLP-C and adverse prognosis with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing percutaneous intervention (PCI) identify potential impact of metabolism on predictive value RLP-C. Methods: enrolled 2419 NSTE-ACS who underwent PCI at Beijing Anzhen...

10.21203/rs.3.rs-33302/v1 preprint EN cc-by Research Square (Research Square) 2020-06-08

Abstract Background: The relationship between triglycerides-glucose index (TyG index) and the prevalence prognosis of cardiovascular disease has been confirmed by former studies. However, it remains uncertain whether TyG a prognostic impact in patients with type 2 diabetes mellitus (T2DM) non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing percutaneous intervention (PCI). Methods: study retrospectively enrolled 798 (mean age: 60.9 ± 8.3 years; 68.3% men) T2DM NSTE-ACS who...

10.21203/rs.3.rs-28546/v2 preprint EN cc-by Research Square (Research Square) 2020-06-26

Abstract Background: Coronary artery bypass grafting (CABG) success is reduced by graft occlusion. Patients with type 2 diabetes mellitus(T2DM) are more likely to develop Understanding factors associated occlusion may improve T2DM patient outcomes. The aim of this study was a predictive risk score for saphenous vein (SVG) in patients after CABG. Methods: This retrospective cohort enrolled 3716 CABG from January 2012 March 2013. development included 2477 and the validation 1239 patients....

10.21203/rs.3.rs-44228/v1 preprint EN cc-by Research Square (Research Square) 2020-08-04
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