Dainius Karčiauskas

ORCID: 0000-0003-2967-3471
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Aortic Disease and Treatment Approaches
  • Aortic aneurysm repair treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular Function and Risk Factors
  • Plant Micronutrient Interactions and Effects
  • Aortic Thrombus and Embolism
  • Cardiac electrophysiology and arrhythmias
  • Magnesium in Health and Disease
  • Mechanical Circulatory Support Devices
  • Neuroscience and Neural Engineering
  • Coronary Interventions and Diagnostics
  • Optical Imaging and Spectroscopy Techniques
  • Analytical Chemistry and Sensors
  • Orthopedic Infections and Treatments
  • Congenital Heart Disease Studies
  • Cardiac tumors and thrombi
  • Infectious Aortic and Vascular Conditions
  • Acute Myocardial Infarction Research
  • Pulmonary Hypertension Research and Treatments
  • Heart Rate Variability and Autonomic Control
  • Shoulder and Clavicle Injuries
  • Ion Channels and Receptors

Lithuanian University of Health Sciences
2016-2025

Hospital of Lithuanian University of Health Sciences Kaunas Clinics
2022

Herein, we review the critical role of a multi-disciplinary team approach in managing intricate complications ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). Mechanical circulatory support (MCS) implantation represents potentially life-saving intervention, often serving as bridge to heart transplantation (HTx). However, from prior interventions, patients receiving MCS due STEMI-CS, may present additional challenges successful HTx candidacy. A 63-year-old...

10.1080/14796678.2025.2471732 article EN Future Cardiology 2025-02-26

Magnesium-sensitive transient receptor potential melastatin (TRPM) ion channels, TRPM6 and TRPM7, are present in several organs, but their roles the heart remain unclear. Therefore, here, we studied expression patterns of TRPM7 normal diseased myocardium. Cardiac atrial tissue cardiomyocytes were obtained from healthy pigs undiseased human hearts as well patients with ischemic disease (IHD) or fibrillation (AF). Immunofluorescence ELISA used to detect TRP proteins. immunofluorescence...

10.3390/ijms232314860 article EN International Journal of Molecular Sciences 2022-11-28

Introduction: To evaluate early and long-term clinical outcomes following aortic valve sparing root reimplantation surgery in patients with leaking bicuspid tricuspid valves. Methods: The study consisted of 92 consecutive adult (tricuspid group = 63 29) who underwent or without cusp repair for dilatation the and/or regurgitation at our institution from April 2004 to October 2016. Clinical were investigated using Kaplan–Meier log-rank tests between groups. Results: follow-up was 100% complete...

10.1177/0267659119831926 article EN Perfusion 2019-03-01

Objective: Surgical management of infective endocarditis continues to be challenging and is associated with significant morbidity mortality. The objective our study was determine the risk factors conditions poor early surgical treatment outcomes—30-day postoperative Methods: A total 124 patients who underwent surgery for at Hospital Lithuanian University Health Sciences Kaunas Clinics from January 2010 December 2017 were retrospectively included in this study. primary endpoints 30-day...

10.1177/0267659119872345 article EN Perfusion 2019-09-04

Aortic valve sparing surgery (AVS), in combination with aortic cusp repair (ACR), still raises many questions about the increased surgical complexity and applicability for patients pure regurgitation (AR). The aim of this study was to investigate our long-term outcomes predictors recurrent AR (> 2+) after AVS reconstructive surgery.We reviewed data 81 who underwent (a reimplantation technique) concomitant ACR or dilatation root at institution during period from April 2004 October 2016. On...

10.1186/s13019-019-1019-3 article EN cc-by Journal of Cardiothoracic Surgery 2019-11-12

Abstract The emergence of optical imaging has revolutionized the investigation cardiac electrical activity and associated disorders in various pathologies. signals heart propagation pathways are crucial for elucidating mechanisms pathological conditions, including arrhythmia. synthesis near-infrared voltage-sensitive dyes voltage sensitivity FDA-approved dye Cardiogreen have increased importance mapping (OM) as a prospective tool clinical practice. We aimed to develop method...

10.1038/s41598-020-65464-5 article EN cc-by Scientific Reports 2020-05-22

The expression of the channels-enzymes TRPM6 and TRPM7 in human heart remains poorly defined, is generally considered not to be expressed cardiomyocytes. We examined their at protein mRNA levels using right atrial samples resected from patients (n = 72) with or without ischemic disease (IHD) all chamber walls explanted hearts 9). proteins were detected immunofluorescence on isolated cardiomyocytes, ELISA tissue homogenates, immunostaining cardiac tissue, whereas mRNAs by RT-qPCR. Both...

10.1038/s41598-021-94856-4 article EN cc-by Scientific Reports 2021-07-29

To evaluate different aortic root surgery techniques and their contemporary clinical outcomes in patients with regurgitant valve aneurysm.The study consisted of 141 adult who underwent reimplantation (David group = 73) or replacement (Bentall 68) for regurgitation (AR) dilatation the at our institution within same period (April 2004-October 2016). Kaplan-Meier method was used to estimate survival other clinically relevant between groups.The completeness follow-up 100%, a mean time 8.0 ± 3.8...

10.1177/02676591221080512 article EN Perfusion 2022-03-26

To evaluate the impact of concomitant tricuspid valve (TV) repair on right ventricular (RV) function postoperatively and within 6 months following degenerative mitral (MV) repair.The prospective study included 37 patients (mean age 57.32 ± 2.13 years) with severe MV regurgitation due to primary prolapse. Nineteen underwent successful (TV(-) group). Additional TV moderate-to-severe was performed in 18 (TV(+) Two-dimensional (2D) speckle-tracking tissue Doppler echocardiography for all before...

10.1177/0267659118820776 article EN Perfusion 2018-12-31

Introduction Patients with primary mitral regurgitation (MR) usually remain asymptomatic for a long time due to compensatory mechanisms and an adequate treatment could be delayed. Stress echocardiography speckle-tracking analysis help evaluate impaired left atrium (LA) function before the manifestation of clinically significant myocardial changes in patients MR preserved ventricular (LV) ejection fraction (EF). Methods This study prospectively enrolled 91 LV EF (≥60%) at rest, which 60 had...

10.1177/02676591241251441 article EN Perfusion 2024-04-30

The aim of the study was to evaluate early postoperative results different surgical techniques aortic root surgery. Material and methods. Between January 2004 November 2007, a cohort 83 patients underwent surgery in Heart Center, Hospital Kaunas University Medicine. Patients were divided into three groups: Group 1 (18 patients) – reimplantation valve within vascular graft (David operation), 2 (48 replacement ascending aorta using valved conduit (Bentall de Bono 3 (17 biological replacement....

10.3390/medicina45030026 article EN cc-by Medicina 2009-03-10

Introduction Isolated coronary ostial stenosis of both ostia is a rare, potentially life-threatening condition, occurring in 0.1%–0.2% patients undergoing angiography. Case report We present case 69-year-old woman with past medical history breast cancer, who had been treated radiotherapy, which most likely caused significant and accelerated aortic stenosis. Surgical angioplasty autopericardium patch reconstruction the left main artery right arteries due to proximal stenotic disease was...

10.1177/02676591231221707 article EN cc-by Perfusion 2023-12-08

Straipsnyje apžvelgiami dviburio aortos vožtuvo (DAV) etiologiniai veiksniai, diagnostikos ir chirurginio gydymo galimybės. Naujausios mokslinės literatūros paieška atlikta PubMed UpToDate mokslinėse duomenų bazėse. Į sisteminę apžvalgą įtraukta 30 straipsnių nagrinėjama tema. Tyrimo rezultatai atskleidė, kad DAV yra viena dažniausių įgimtų širdies ydų, kuri gali būti izoliuota patologija arba kartu su kitomis įgimtomis kardiovaskulinės sistemos ydomis bei genetiniais sindromais. morfologija...

10.35988/sm-hs.2021.007 article LT Health Sciences 2021-02-06
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