Herein, we review the critical role of a multi-disciplinary team approach in managing intricate complications ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). Mechanical circulatory support (MCS) implantation represents potentially life-saving intervention, often serving as bridge to heart transplantation (HTx). However, from prior interventions, patients receiving MCS due STEMI-CS, may present additional challenges successful HTx candidacy. A 63-year-old...

Relative expression of lncRNAs CARMN, LUCAT1, SMILR, and MALAT1 was tested in clinical aortic tissue blood plasma samples from TAA non-TAA patients using the qRT-PCR method. The Mann-Whitney U test used to compare ΔCt values between study groups. ROC curve analysis performed evaluate diagnostic value lncRNAs. We found significantly reduced CARMN (p = 0.033) LUCAT1 0.009) patients. 0.117) SMILR 0.610) did not differ Expression both decreased patients' compared controls 0.018 p 0.032,...

A clinical effect of warfarin depends on highly polymorphic drug-metabolizing (CYP2C9) and drug-target (VKORC1) enzymes. The objective this study was to investigate the impact CYP2C9*2, CYP2C9*3, VKORC1 (G-1639A) polymorphisms variability dosage requirements in Lithuanian patients after heart valve replacement.The included 83 with a mean age 65.2 years (SD, 13.31) replacement an achieved stable international normalized ratio 2-3.5. restriction fragment length polymorphism method used...

Introduction: To evaluate early and long-term clinical outcomes following aortic valve sparing root reimplantation surgery in patients with leaking bicuspid tricuspid valves. Methods: The study consisted of 92 consecutive adult (tricuspid group = 63 29) who underwent or without cusp repair for dilatation the and/or regurgitation at our institution from April 2004 to October 2016. Clinical were investigated using Kaplan–Meier log-rank tests between groups. Results: follow-up was 100% complete...

Abstract Background The dry‐pericardium Vienna transcatheter aortic valve system is repositionable and retrievable, already premounted on the delivery system, eliminating need for assembly crimping of device before implantation. Methods VIVA first‐in‐human feasibility study, a prospective, nonrandomized, single‐center trial, evaluated in 10 patients with severe symptomatic stenosis, who were at intermediate or high surgical risk. This registered ClinicalTrials.gov (NCT04861805), focused...

The aim of study was to assess the effects an intraoperative external head-cooling technique on cognitive dysfunction in early postoperative period (at 10th day) patients after coronary artery bypass graft (CABG) surgery. Patients Group H (n=25) were cooled with CPB and intraoperative, technique, C only cardiopulmonary (CPB) achieve mild hypothermia (33 – 34°C). Cognitive function analyzed before operation surgery using Mini Mental State Examination (MMSE), Modified Visual Reproduction Test...

Objective: Surgical management of infective endocarditis continues to be challenging and is associated with significant morbidity mortality. The objective our study was determine the risk factors conditions poor early surgical treatment outcomes—30-day postoperative Methods: A total 124 patients who underwent surgery for at Hospital Lithuanian University Health Sciences Kaunas Clinics from January 2010 December 2017 were retrospectively included in this study. primary endpoints 30-day...

Aortic valve sparing surgery (AVS), in combination with aortic cusp repair (ACR), still raises many questions about the increased surgical complexity and applicability for patients pure regurgitation (AR). The aim of this study was to investigate our long-term outcomes predictors recurrent AR (> 2+) after AVS reconstructive surgery.We reviewed data 81 who underwent (a reimplantation technique) concomitant ACR or dilatation root at institution during period from April 2004 October 2016. On...

Despite improvements over time with regard to morbidity, mortality, and long-term survival, deep sternal wound infection (DSWI) continues be a major complication after open-heart surgery. This is why it important identify possible risk factors for postoperative development of DSWI in patients undergoing coronary artery bypass grafting valve replacement. The aim this study was the heart defect surgery at Department Thoracic, Cardiac, Vascular Surgery Hospital Lithuanian University Health...

Thermography is a relatively new contact-free method used in experimental and clinical studies cardiovascular surgery to investigate the myocardium coronary artery function. Objects of complex study included mongrel dogs patients with disease who underwent cardiac surgery. For active dynamic thermography, we thermovision camera “A20V” (FLIR Systems, USA). Our data indicate that both performed on beating hearts could be an important approach interoperation inspection autovenous graft An...

The main goal of this manuscript was to evaluate the diagnostic value global and regional postsystolic shortening (PSS) parameters, assessed by two-dimensional (2D) speckle-tracking echocardiography, at rest during dobutamine stress for detection functionally significant coronary artery stenoses in patients with moderate pretest probability stable disease (CAD).Dobutamine echocardiography (DSE) adenosine myocardial perfusion imaging cardiac magnetic resonance (CMR-MPI) were performed on 83...

To evaluate the association between histologically verified left ventricular (LV) myocardial fibrosis (MF) and its bio- functional markers with pulmonary hypertension (PH) in severe aortic stenosis (AS).About 34 patients isolated AS underwent 2D echocardiography, cardiac magnetic resonance (CMR) imaging, plasma NT-proBNP evaluation before valve replacement (AVR). LV measurements were analyzed by CMR strain using feature tracking software (Medis Suite QStrain 2.0). Myocardial biopsy sampled...

To evaluate late outcomes after posterior mitral valve (MV) annulus double-suture annuloplasty for degenerative (non-ischaemic) MV insufficiency.Between 2005 and 2011, 138 patients underwent repair using an additional 105 tricuspid repair. The study protocol included operative mortality, reoperation rate reasons, as well echocardiographic parameters at pre- postoperative follow-up periods (2-9 years).In-hospital mortality was 2/138 (1.45%). Early post operation, no regurgitation noted in...

To evaluate different aortic root surgery techniques and their contemporary clinical outcomes in patients with regurgitant valve aneurysm.The study consisted of 141 adult who underwent reimplantation (David group = 73) or replacement (Bentall 68) for regurgitation (AR) dilatation the at our institution within same period (April 2004-October 2016). Kaplan-Meier method was used to estimate survival other clinically relevant between groups.The completeness follow-up 100%, a mean time 8.0 ± 3.8...

The goal of this study was to investigate the movement contraction-relaxation effects on isolated human blood vessel samples by actions amlodipine (CAS 88150-42-9), cerebrocrast 118790-71-9), diltiazem 42399-41-7), and a benzimidazole derivative. Additionally, their isometric contraction force duration action potential (AP) were measured. experiments carried out v. saphena magna papillary muscles adult guinea pigs. Isometric AP recorded using transducer standard microelectrode technique....

Successful heart-lung complex transplantation was performed in a 48-year-old man. During the postoperative period, M. tuberculosis infection diagnosed, and treatment subsequently started. One year after, patient urgently hospitalized due to myocardial infarction. However, despite best efforts, died. Antituberculosis is recommended all patients with confirmed active tuberculosis. Treatment of transplant recipients similar that general population, exclusion rifamycins regimen longer duration treatment.

Abstract Background: There are many studies comparing surgical (SAVR) and transcatheter (TAVR) aortic valve replacement, but in most cases patients with complex coronary artery disease (CAD) were excluded from the trials. Aim: To evaluate clinical outcomes echocardiography parameters of TAVR percutaneous intervention (PCI) compared SAVR arteries bypass grafting (CABG) procedures concomitant stenosis (AS) CAD. Methods: Retrospective study involved 200 significant AS CAD, requiring prosthetic...

Abstract Introduction There is growing concern about the recurrence of tricuspid regurgitation (TR) after annuloplasty (TA) in individuals with functional (FTR). While TA effective treating FTR, a comprehensive understanding echocardiographic factors influencing TR crucial. Aim This study aims to employ multivariate regression analysis investigate prognostic significance valve (TV) geometry and parameters associated both RV function. The focus on comprehending these relationships context...

Abstract Introduction The increasing worry revolves around the reappearance of tricuspid regurgitation (TR) following annuloplasty (TA) among individuals dealing with functional (FTR). Despite TA's efficacy as a treatment, complete understanding echocardiographic elements influencing recurrence TR is pivotal. This knowledge holds potential to guide development more robust preventive strategies, aiming ease incidence recurrent after TA. Aim aim this study was examine prognostic value valve...