A5031994258- Circadian rhythm and melatonin
- Dietary Effects on Health
- Sleep and Wakefulness Research
- Bat Biology and Ecology Studies
- Neurobiology and Insect Physiology Research
- Neuroendocrine regulation and behavior
- Adipose Tissue and Metabolism
- Gastric Cancer Management and Outcomes
- Indigenous Studies and Ecology
- Environmental DNA in Biodiversity Studies
- Sleep and related disorders
- Enhanced Recovery After Surgery
- Diet and metabolism studies
- Gut microbiota and health
- Bariatric Surgery and Outcomes
- Physiological and biochemical adaptations
- Psychological and Temporal Perspectives Research
University of Groningen
2014-2022
University Hospital Leipzig
2022
Significance The circadian system drives daily rhythms in physiology and behavior. Mammals nature can change their activity rhythms, but causes consequences of this behavioral plasticity are unknown. Here we show that nocturnal mice become diurnal when challenged by cold or hunger. Negative energy balance changes hormonal, physiological without modifying the rhythm pacemaker suprachiasmatic nucleus. This response is adaptive because during daytime warmth resting a buffered environment...
Abstract Maximising survival requires animals to balance the competing demands of maintaining energy and avoiding predation. Here, quantitative modelling shows that optimising daily timing activity rest based on encountered environmental conditions enables small mammals maximise survival. Our model nocturnality is typically beneficial when predation risk higher during day than night, but this reversed by energetic benefit diurnality food becomes scarce. Empirical testing under semi‐natural...
Abstract Background Bariatric surgery remains the most effective therapy for adiposity reduction and remission of type 2 diabetes. Although different bariatric procedures associate with pronounced shifts in gut microbiota, their functional role regulation energetic metabolic benefits achieved are not clear. Methods To evaluate causal as well inherent therapeutic character surgery-altered microbiome improved energy control diet-induced obesity, an antibiotic cocktail was used to eliminate...
ABSTRACT Endogenous daily (circadian) rhythms allow organisms to anticipate changes in the environment. Most mammals are specialized be active during night (nocturnal) or day (diurnal). However, typically nocturnal become diurnal when energetically challenged by cold hunger. The circadian thermo-energetics (CTE) hypothesis predicts that activity patterns reduce energy expenditure (DEE) compared with patterns. Here, we tested CTE quantifying energetic consequences of relevant environmental...
Circadian (~24 h) rhythms in behavior and physiological functions are under control of an endogenous circadian pacemaker the suprachiasmatic nucleus (SCN) hypothalamus. The SCN directly drives some these or serves as a coordinator peripheral oscillators residing other tissues organs. Disruption organization may contribute to disease, including stress-related disorders. Previous research indicates that master clock is resistant stress, although it unclear whether stress affects rhythmicity...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)