Ticks are an important but under recognized parasitic threat to cats in many areas of the United States. To characterize species and stages ticks most commonly recovered from determine prevalence disease agents ticks, we conducted a survey removed at veterinary practices 18 states April 2016-June 2017. A total 796 were submitted 332 41 different practices. single tick was majority cats, with mean infestation intensity 2.4 (range 1-46). The common Ixodes scapularis, accounting for 422/796...

Adherence to a prescribed therapeutic regimen is critical factor for achieving medication effectiveness and therefore treatment success. In the case of companion animal ectoparasite control, suboptimal owner adherence recommendations thought be common cause failure, previous reports have found pet owners applying an average 4.0-4.6 monthly flea tick treatments per year their dogs. This study investigated: US veterinary hospital self-reported prevention recommendations; dog recollection these...

Species of Canidae in Russia can be infested with up to 24 different tick species; however, the frequency species infesting domestic dogs across is not known. In addition, tick-borne disease risks for are well quantified. The goal this study was conduct a nationwide survey ticks collected from admitted veterinary clinics Russian cities and identify pathogens found these ticks. Ticks feeding on 32 27 major were preserved ethanol submitted central facility examination. After identification,...

The geographical distribution of ticks on companion animals needs to be monitored develop and plan effective control measures, as suggested by the European Scientific Counsel Companion Animal Parasites. aim this study was conduct first Italian national survey tick privately owned dogs.The performed over 20 months (February 2016 - September 2017) involved 153 veterinary practices in 64 different provinces covering 17/20 (85%) regions. Participating practitioners were asked examine five dogs...

The clinical efficacy of fluralaner chewable tablets (Bravecto™, MSD Animal Health) against naturally acquired Linognathus setosus infestations on dogs was evaluated compared with permethrin (Exspot®, treatment.Privately-owned infested L. from 21 different households were randomly allocated to two treatment groups. Fourteen treated once orally and ten topically permethrin, at the recommended label dose. Live all counted before 1, 7, 28 (both groups) 84 (fluralaner group) days post-treatment...

Acaricides are used to treat and prevent tick infestations, a common clinical scenario is administer an acaricide on observing attached tick. Consequently, immediate acaricidal efficacy (onset of activity speed kill) results clinically valuable. This study evaluated the four commercially available acaricides against adult Rhipicephalus sanguineus (sensu lato). Forty dogs were blocked hair length carrying capacity, then randomly assigned receive one treatments (fluralaner, sarolaner,...

Veterinary clinic transaction records from the USA were examined to determine dog owner purchase patterns for three prescription ectoparasiticides. In-clinic purchases of formulations fluralaner (with 12-week duration per dose) compared with afoxolaner and spinosad (both 4 week in a population 231,565 dogs over 12 month period. Prior studies human animal medicine have suggested that patients more closely adhere prescriber dosing recommendations when they receive longer-duration medication....

Dipylidium caninum is a common tapeworm of dogs contracted from ingestion fleas containing the infective cysticercoid stage. Fluralaner systemically distributed isoxazoline class insecticide that delivers highly effective activity against and ticks for up to 12 weeks after single oral or topical treatment. This study evaluated impact this flea insecticidal efficacy on transmission D. dogs. Dogs were weighed treated with cestocide then randomly assigned 3 groups 8. was administered topically...

Doses of flea and tick medication acquired by dog owners over a 12 month period were determined from veterinary hospital transaction records in Spain. The number months protection potentially obtained prescribed fluralaner, with week re-dosing interval, was compared monthly oral or spot-on products. Prior studies human medicine have suggested that longer-acting medications benefit patients providing improved adherence to provider recommendations. Dog took home, on average, significantly more...

Haemaphysalis longicornis ticks represent an ectoparasitic health threat to dogs. This study evaluated the immediate and persistent efficacy of orally administered fluralaner for control this tick.Twenty-four dogs were sorted into 4 groups based on their tick carrying capacity measured in a preliminary challenge. Two days before treatment, challenged with then at time treatment received oral 10, 25 or 50 mg/kg respectively 3 groups, while remaining group was sham treated. Ticks counted...

Abstract Background Convergent evidence indicates that deficits in the endosomal recycling pathway underlies pathogenesis of Alzheimer’s disease (AD). SORL1 encodes retromer‐associated receptor SORLA plays an essential role AD‐associated cargos such as amyloid precursor protein and glutamatergic AMPA receptor. Importantly, loss function pathogenic variants are associated with AD. Moreover, both retromer levels reduced most vulnerable regions AD brains. Thus, restoration via viral...

An extended duration flea and tick medication of the isoxazoline class (fluralaner) was introduced in 2014 United States other countries. A survey developed 2016 to gauge dog owner adherence with veterinary recommendations around administration preventive medications. Current fluralaner-using owners were also asked compare their experience opinions on monthly products.To who current users fluralaner opinions, experiences, attitudes medications dogs light veterinarian recommendations.Dog...

Abstract Background Adult, nymph, and larval Rhipicephalus sanguineus sensu lato infest dogs thrive in premises including homes kennels. Ticks emerge from hiding to seek attach dogs, engorge, then leave their hosts hide molt or oviposit. This study evaluated the effect of either external systemic canine treatment on R. s.l. populations premises. Methods Thirty-two eight kennels were divided into three groups; one group (eight two kennels) served as untreated controls; (12 received oral...

Abstract Background Flea bite is considered to be the main cause of allergic dermatitis in cats. There a need for treatments able control clinical signs associated with flea This was an open pre-treatment versus post-treatment field study. All cats included study presented pruritus, skin lesions or other evidence compatible infestation. Skin were assessed (using SCORFAD) at days 0, 28, 56 and 84 whereas pruritus severity PVAS) 15, 84. On day The fluralaner (280 mg/ml) product (Bravecto®...

Abstract Background Safe and effective flea tick treatment options for cats are important in companion animal practice because of feline ectoparasite infestation prevalence the potential parasitic disease transmission. Retrospective cat owner purchasing transactions at United States America (USA) veterinary clinics were obtained three topical ectoparasiticides. One medication, fluralaner, had a 12-week redosing interval, while two other medications (fipronil/s-methoprene/pyriproxyfen;...

The banning by the New Zealand Government of import and export asbestos-containing products resulted from interplay a number factors. At personal level, there were actions asbestos sufferers, their families support groups. political activities progressive trade union groups representing hazardous trades, such as labourers, construction workers demolition workers, at was positive response to these public health pressures. Prohibition Order 2016 concerning Imports Exports (asbestos-containing...

South African veterinarians report the perception of a multi-year decline in number dogs presenting with clinical babesiosis, common and serious disease country. This study tested this observation through analysis veterinary hospital medical records from 2011 2016.Medical were collected 44 participating hospitals. The searched to enumerate Babesia-specific medication treatments administered at all A healthcare use rate was calculated for canine babesiosis treatment each calendar year 2016....