A5040459117- Metabolomics and Mass Spectrometry Studies
- Nutritional Studies and Diet
- Gut microbiota and health
- Diet and metabolism studies
- Children's Physical and Motor Development
- Social Policies and Healthcare Reform
- Social and Demographic Issues in Germany
- Health and Medical Studies
- Muscle metabolism and nutrition
- Adipose Tissue and Metabolism
- Cardiovascular and exercise physiology
- Health, Environment, Cognitive Aging
Max Rubner Institut
2016-2023
The human metabolome is influenced by various intrinsic and extrinsic factors. A precondition to identify such biomarkers the comprehensive understanding of composition variability healthy humans. Sample handling aspects have an important impact on metabolome; therefore, it crucial for any metabolomics study standardize protocols sample collection, preanalytical handling, storage, analytics keep nonbiological as low possible.The main objective KarMeN analyze in blood urine targeted...
Knowledge on metabolites distinguishing the metabolic response to acute physical exercise between fit and less individuals could clarify mechanisms pathways contributing beneficial adaptations exercise. By analyzing data from cross-sectional KarMeN (Karlsruhe Metabolomics Nutrition) study, we characterized effects of a standardized tolerance test urinary 255 healthy women men. In second step, aimed detect metabolite pattern associated with cardiorespiratory fitness (CRF), which was...
Introduction: Endurance exercise alters whole-body as well skeletal muscle metabolism and physiology, leading to improvements in performance health. However, biological mechanisms underlying the body's adaptations different endurance protocols are not entirely understood. Methods: We applied a multi-platform metabolomics approach identify urinary metabolites associated metabolic pathways that distinguish acute response two interventions at distinct intensities. In our randomized crossover...
On the national level, nutritional monitoring requires assessment of reliable representative dietary intake data. To achieve this, standardized tools need to be developed, validated, and kept up-to-date with recent developments in food products behavior population. Recently, human intestinal microbiome has been identified as an essential mediator between nutrition host health. Despite growing interest this connection, only a few associations microbiome, nutrition, health have clearly...
<sec> <title>BACKGROUND</title> On the national level, nutritional monitoring requires assessment of reliable representative dietary intake data. To achieve this, standardized tools need to be developed, validated, and kept up-to-date with recent developments in food products behavior population. Recently, human intestinal microbiome has been identified as an essential mediator between nutrition host health. Despite growing interest this connection, only a few associations microbiome,...