A5031103041- Aquaculture Nutrition and Growth
- Invertebrate Immune Response Mechanisms
- Reproductive biology and impacts on aquatic species
- Aquaculture disease management and microbiota
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Marine Bivalve and Aquaculture Studies
- Fish Ecology and Management Studies
- Environmental Toxicology and Ecotoxicology
- Effects and risks of endocrine disrupting chemicals
- Crustacean biology and ecology
- Identification and Quantification in Food
- Viral Infectious Diseases and Gene Expression in Insects
- Pharmaceutical and Antibiotic Environmental Impacts
- Viral Infections and Vectors
- Genetic and phenotypic traits in livestock
- Aquatic Ecosystems and Biodiversity
- Estrogen and related hormone effects
- Genetic diversity and population structure
- Marine and fisheries research
- Animal Genetics and Reproduction
- Parasite Biology and Host Interactions
- Mosquito-borne diseases and control
- Zebrafish Biomedical Research Applications
- Plant Virus Research Studies
- Animal Behavior and Reproduction
University of Exeter
2009-2024
National Institutes of Natural Sciences
2009
University of Sussex
2009
Okazaki Institute for Integrative Bioscience
2009
AstraZeneca (United Kingdom)
2009
Abstract Intricate links between aquatic animals and their environment expose them to chemical pathogenic hazards, which can disrupt seafood supply. Here we outline a risk schema for assessing potential impacts of microbial hazards on discrete subsectors aquaculture—and control measures that may protect As national governments develop strategies achieve volumetric expansion in production from aquaculture meet increasing demand, propose an urgent need simultaneous focus controlling those...
The European shore crab, Carcinus maenas, is used widely in biomonitoring, ecotoxicology and for studies into host-pathogen interactions. It also an important invasive species numerous global locations. However, the genomic resources this organism are still sparse, limiting research progress these fields. To address resource shortfall we produced a C. maenas transcriptome, enabled by next-generation sequencing technologies, applied to assemble information on innate immune system species.We...
Diclofenac is one of the most widely prescribed nonsteroidal anti-inflammatory drugs worldwide. It frequently detected in surface waters; however, whether this pharmaceutical poses a risk to aquatic organisms debated. Here we quantified uptake diclofenac by fathead minnow (Pimephales promelas) following aqueous exposure (0.2-25.0 μg L-1) for 21 days, and evaluated tissue biomolecular responses kidney. accumulated concentration- time-dependent manner plasma exposed fish. The highest...
Many factors have been considered in evaluations of the risk−benefit balance hormone replacement therapy (HRT), used for treating menopausal symptoms women, but not its potential risks environment. We investigated possible environmental health implications conjugated equine estrogens (CEEs), most common components HRT, including their discharge into environment, uptake, potency, and ability to induce biological effects wildlife. Influents effluents from four UK sewage treatment works (STWs),...
Laboratory animals tend to be more inbred and less genetically diverse than wild populations, thus may differ in their susceptibility chemical stressors. We tested this hypothesis by comparing the responses of related (theoretical inbreeding F(IT) = n + 0.25) outbred (F(IT) n) zebrafish (Danio rerio) WIK/Wild family lines an endocrine disrupting chemical, clotrimazole. Exposure 2.9 μg clotrimazole/L had no effect on survival, growth, or gonadal development. both 43.7 led male-biased sex...
Hypoxia is a global and increasingly important stressor in aquatic ecosystems, with major impacts on biodiversity worldwide. Hypoxic waters are often contaminated wide range of chemicals but little known about the interactions between these stressors. We investigated effects hypoxia responses zebrafish (Danio rerio) embryos to copper, widespread contaminant. showed that during continuous exposures copper toxicity was reduced by over 2-fold under compared normoxia. When were conducted 24 h...
Shellfish mariculture, the farming of marine bivalve shellfish, is a highly sustainable form food production, which contributes significantly to rural, coastal economies England and Wales, has considerable potential for growth. To unlock this potential, we explored application positive tipping points (PTP) framework in an invited stakeholder workshop comprising key policy makers, regulators, industry representatives academic researchers. Stakeholders mapped environmental socio-economic...
White Spot Disease (WSD) presents a major barrier to penaeid shrimp production. Mechanisms underlying Syndrome Virus (WSSV) susceptibility in penaeids are poorly understood due limited information related early infection. We investigated mRNA and miRNA transcription Penaeus vannamei over 36 h following Over this time course, 6192 transcripts 27 miRNAs were differentially expressed-with differential expression from 3-12 post injection (hpi) more significant transcriptional response associated...
Inbreeding depression is expected to be more severe in stressful environments. However, the extent which inbreeding affects vulnerability of populations environmental stressors, such as chemical exposure, remains unresolved. Here we report on combined impacts and exposure an endocrine disrupting (the fungicide clotrimazole) zebrafish (Danio rerio). We show that whilst can negatively affect reproductive traits, not all traits are affected equally. frequently only became apparent when fish...
Introduction All decapod crustaceans are considered potentially susceptible to White Spot Syndrome Virus (WSSV) infection, but the degree of Disease (WSD) susceptibility varies widely between species. The European shore crab Carcinus maenas can be infected with virus for long periods time without signs disease. Given high mortality rate species, differential these resistant hosts offers an opportunity investigate mechanisms disease resistance. Methods Here, temporal transcriptional responses...
Exposure to environmental estrogens in wastewater treatment works (WwTW) effluents induces feminized responses male fish, including the development of eggs testes. However, impacts on offspring exposed fish are not well understood. In this study, we examined whether roach (Rutilus rutilus) from mothers that had been an undiluted WwTW effluent early life sexual maturity altered susceptibility gonadal feminization and impaired capacity reproduce. For males both dilution water mothers, exposure...