A5043121572- Rheumatoid Arthritis Research and Therapies
- Multiple Sclerosis Research Studies
- Autoimmune and Inflammatory Disorders Research
- Folate and B Vitamins Research
- Cerebral Palsy and Movement Disorders
- Childhood Cancer Survivors' Quality of Life
- Antibiotic Resistance in Bacteria
- T-cell and Retrovirus Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Spondyloarthritis Studies and Treatments
- Family Support in Illness
- Medicinal Plants and Bioactive Compounds
- Medical Imaging and Pathology Studies
- Polyomavirus and related diseases
- Bacterial biofilms and quorum sensing
- Heterotopic Ossification and Related Conditions
- Systemic Lupus Erythematosus Research
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Genetic Syndromes and Imprinting
- Pharmaceutical and Antibiotic Environmental Impacts
University of Medicine and Pharmacy of Craiova
2019-2022
The study aims to explore the oxidative status related inflammation in peripheral blood of stable relapsing-remitting multiple sclerosis (MS) patients with low disability. In this study, 31 people were included and divided into two groups: an MS group which 16 a disability level (age 38.9 ± 7.08, EDSS median 2.5) control that contains 15 healthy volunteers similar age group. Thiobarbituric acid reactive substances (TBARS), protein carbonyl (PCO), total antioxidant capacity (TAC) as stress...
Rheumatoid arthritis (RA) is a chronic progressive autoimmune disease, associated with significant morbidity, mainly due to damage and consequent disability. Oxidative stress an important part of RA pathophysiology, as in disease the interaction between immune response endogenous/exogenous antigens subsequently induce production reactive oxygen species. The oxidative process seems be positively strongly correlated inflammation accelerated joint destruction. We were asking ourselves if...
CTX-M betalactamases have shown a rapid spread in the recent years among Enterobacteriaceae and become most prevalent Extended Spectrum Beta-Lactamases (ESBLs) many parts of world. The introduction dissemination antibiotic-resistant genes limits options for treatment, increases mortality morbidity patients, leads to longer hospitalization expensive costs. We aimed identify beta-lactamases circulating encoded by blaCTX-M-15, blaSHV-1 blaTEM-1 Escherichia coli (E. coli) Klebsiella pneumoniae...
Myositis ossificans (MO) is a rare, benign ossifying lesion characterized by focal formation of heterotopic bone and cartilage in extraskeletal soft‑tissue that most commonly occurs young adults. In cases, no causative factor can be identified. The diagnosis MO usually based on the patient's history trauma, clinical signs, imaging appearance histological examination. We present non‑traumatic case forearm 40‑year‑old man with weakness left finger motion, decrease prehension for more than...
Multiple sclerosis (MS) is a progressive and irreversible disease which affects the central nervous system (CNS) with still unknown etiology. Our study aimes to establish homocysteine pattern that can predict MS diseases progression identify potential marker be easy perform non-invasive, in order outcome. In achieve this goal, we included 10 adult RRMS subjects, SPMS subjects age-matched healthy subjects. The plasma level was measured using automated latex enhanced immunoassay cobalamin...
Multiple sclerosis (MS) is a chronic, severe disease, characterized by progressive alteration in neuronal transmission, which decreases personal independence and quality of life (QoL). This study aimed to investigate the relationship between QoL autonomy patients with MS, as well its correlation age, educational level, diseases severity. Twenty-six MS were followed-up for six months. All completed 15D questionnaire two times: at T0, when they started new treatment, T1 after months treatment....
Musculoskeletal disorders are the leading cause of long term disability in EU with a significant impact on health care system and increased social economic costs. Despite recent advances Rheumatoid arthritis (RA) research field, here is still lacking specific biomarkers that can be used order to distinguish between different RA patterns clinical criteria main tool only for classification diseases. Our hypothesis vitamin deficiency associated chronic inflammation lead mild increase Hcy level...