A5063067335- Antibiotic Resistance in Bacteria
- HIV Research and Treatment
- Antibiotic Use and Resistance
- Urinary Tract Infections Management
- Ocular Infections and Treatments
- Hepatitis B Virus Studies
- Ocular Oncology and Treatments
- Hepatitis C virus research
- Immunodeficiency and Autoimmune Disorders
- Bacterial Identification and Susceptibility Testing
- Diabetes and associated disorders
- Nosocomial Infections in ICU
- Pediatric Urology and Nephrology Studies
- Liver Diseases and Immunity
- Liver Disease Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Bacterial biofilms and quorum sensing
- Ear and Head Tumors
- Rheumatoid Arthritis Research and Therapies
- Bone Tissue Engineering Materials
- Antimicrobial Resistance in Staphylococcus
- Herpesvirus Infections and Treatments
- Cancer, Lipids, and Metabolism
- Toxoplasma gondii Research Studies
- Immune Cell Function and Interaction
University of Medicine and Pharmacy of Craiova
2014-2024
Clinical Emergency Hospital Bucharest
2024
Yahoo (United Kingdom)
2019
University of Craiova
2015
CTX-M betalactamases have shown a rapid spread in the recent years among Enterobacteriaceae and become most prevalent Extended Spectrum Beta-Lactamases (ESBLs) many parts of world. The introduction dissemination antibiotic-resistant genes limits options for treatment, increases mortality morbidity patients, leads to longer hospitalization expensive costs. We aimed identify beta-lactamases circulating encoded by blaCTX-M-15, blaSHV-1 blaTEM-1 Escherichia coli (E. coli) Klebsiella pneumoniae...
The most severe infections are invasive infections, due to the fact that germs can accumulate in multiple sites and produce a body-wide infection known as sepsis. Septic shock has highest mortality rate among non-traumatic medical conditions. In this study, we aimed evaluate incidence prevalence of hospital environment. Another second objective was establish aetiology our antibiotic resistance profile involved, which both important for determining therapeutic approach treatment these...
Infectious keratitis is a significant global problem that can lead to corneal blindness and visual impairments. This study aimed investigate the etiology of infectious bacterial fungal keratitis, identify causative pathogens their antimicrobial resistance patterns, analyze risk factors associated with development keratitis. The was observational retrospective, involving 226 eyes from 223 patients presented at Ophthalmology Clinic County Clinical Emergency Hospital Craiova, Romania. inclusion...
Study Motivation: After assessing electronic databases of medical scientific literature, we have observed that the interrelation between urinary tract infections (UTIs) and chronic kidney disease (CKD) is poorly studied, especially when UTIs are caused by Klebsiella pneumoniae (K. pneumoniae).K. was isolated in 14 urine samples from patients with CKD addmited Nephrology Department County Emergency Clinical Hospital Craiova. The strains were statistically analyzed correlation different...
Abstract The main objective of this study was to synthesize hydroxyapatite-ciprofloxacin composites using a chemical precipitation method and evaluate the properties in vitro release profile drug from composites. Composite characterization achieved by FT-IR, XRD DLS. Ciprofloxacin determination accomplished HPLC, resulting good incorporation efficiency (18.13 %). (Higuchi model C = K t 1/2 Ritger-Peppas model, 0.6 ) showed diffusion-controlled mechanism. antibacterial activity that bacterial...
Cytomegalovirus (CMV), in addition to other agents, is part of the TORCH complex (Toxoplasma gondii, Rubella virus, Cytomegalovirus, Herpes simplex viruses, and agents). CMV infection most frequent cause congenital malformations. This study aimed establish variation prevalence anti-CMV antibodies pregnant women from South-West region Romania, according demographic factors, such as age area residence, two separate time periods (2013–2016 2019–2022). We collected hospital records age, place...
The current strategy for treating osteomyelitis includes surgical procedures complete debridement of the formed biofilm and necrotic tissues, systemic oral antibiotic therapy, clinical use cements three-dimensional scaffolds as bone defect fillers delivery systems therapeutic agents. aim our research was to formulate a low-cost hybrid nanoparticulate biomaterial using poly(lactic-co-glycolic acid) (PLGA), in which we incorporated agent (ciprofloxacin), deposit this material on titanium...
To determine the resistance pattern of bacterial pathogens involved in infections patients aged between 18-64 years, admitted a ICU from 1518-bed university-affiliated hospital. A retrospective study was carried out on 351 years to ICU, January December 2017. In this there were analysed 469 samples (18-64 years). total 566 isolates obtained, which 120 strains Klebsiella spp. (35.39%%), followed by Nonfermenting Gram negative bacilli, other than Pseudomonas and Acinetobacter (NFB) (75-...
Accurate diagnosis and early treatment in rheumatoid arthritis (RA) can lead to a good outcome correct management of the disease. We aimed toinvestigate prognostic value anti-RA33 antibodies, by evaluating relationship with ultrasonographic (US) findings patients RA.We performed prospective study which included 29 patients, diagnosed RA according ACR/EULAR 2010 criteria 21 sex age-matched control subjects. All underwent clinical biological assessment, followed US examination grayscale (GS)...
In this study, the antimicrobial activity of three Salvia spp. (S. glutinosa, S. splendens, verticillata) extracts prepared with different solvents was assessed using diffusion method and quantification minimum inhibitory concentration for each extract on aureus, E. coli C. albicans standard strains. The results showed that are suppressing growth bacteria tested variable potency. Among solvent extracts, n-butanolic all species revealed most important antibacterial against aureus coli....
Multiple sclerosis (MS) is a progressive and irreversible disease which affects the central nervous system (CNS) with still unknown etiology. Our study aimes to establish homocysteine pattern that can predict MS diseases progression identify potential marker be easy perform non-invasive, in order outcome. In achieve this goal, we included 10 adult RRMS subjects, SPMS subjects age-matched healthy subjects. The plasma level was measured using automated latex enhanced immunoassay cobalamin...