A5021345731- Electron and X-Ray Spectroscopy Techniques
- Advanced Electron Microscopy Techniques and Applications
- Gas Dynamics and Kinetic Theory
- Integrated Circuits and Semiconductor Failure Analysis
- Genomics and Phylogenetic Studies
- Reservoir Engineering and Simulation Methods
Centre for Artificial Intelligence and Robotics
2020-2021
Abstract Particle identification and selection, which is a prerequisite for high-resolution structure determination of biological macromolecules via single-particle cryo-electron microscopy poses major bottleneck automating the steps determination. Here, we present generalized deep learning tool, CASSPER, automated detection isolation protein particles in transmission microscope images. This tool uses Semantic Segmentation collection visually prepared training samples to capture differences...
Abstract Single-particle cryo-electron microscopy has emerged as the method of choice for structure determination proteins and protein complexes. However, particle identification selection which is a prerequisite achieving high-resolution still poses major bottleneck automating steps determination. Here, we present generalised deep learning tool, CASSPER, automated detection isolation particles in transmission microscope images. This tool uses Semantic Segmentation collection visually...