A5029432126- Horticultural and Viticultural Research
- Fermentation and Sensory Analysis
- Plant tissue culture and regeneration
- Phytochemicals and Antioxidant Activities
- Plant-derived Lignans Synthesis and Bioactivity
- Neuroendocrine regulation and behavior
- Plant-Microbe Interactions and Immunity
- Circadian rhythm and melatonin
- Tryptophan and brain disorders
- Neurobiology and Insect Physiology Research
- Insect and Pesticide Research
- Plant biochemistry and biosynthesis
- Sirtuins and Resveratrol in Medicine
- Wine Industry and Tourism
- Legume Nitrogen Fixing Symbiosis
- Nematode management and characterization studies
- Fungal and yeast genetics research
- Coccidia and coccidiosis research
- Genetic and Environmental Crop Studies
- Allelopathy and phytotoxic interactions
- Helminth infection and control
- Phytochemistry and Biological Activities
- Polyamine Metabolism and Applications
- Microbial Natural Products and Biosynthesis
- Alkaloids: synthesis and pharmacology
Université de Tours
2018-2024
Laboratoire des Biomolécules
2018-2021
Grape canes are waste biomass of viticulture containing bioactive polyphenols valuable in cosmetics. Whereas several studies reported the cosmetic activities E-resveratrol, only few described potential E-ε-viniferin, second major constituent grape cane extracts (GCE), and none them investigated GCE as a natural blend for applications. In this study, we considered from polyphenol-rich varieties multifunctional ingredients. HPLC analysis was performed to quantify i.e., catechin, epicatechin,...
Lochnericine is a major monoterpene indole alkaloid (MIA) in the roots of Madagascar periwinkle (Catharanthus roseus). derived from stereoselective C6,C7-epoxidation tabersonine and can be metabolized further to generate other complex MIAs. While enzymes responsible for its downstream modifications have been characterized, those involved lochnericine biosynthesis remain unknown. By combining gene correlation studies, functional assays, transient inactivation, we identified two highly...
Grape downy mildew is a devastating disease worldwide and new molecular phenotyping tools are required to detect metabolic changes associated plant symptoms. In this purpose, we used UPLC-DAD-MS-based semi-targeted metabolomics screen symptomatic leaves that expressed oil spots (6 dpi, days post-infection) necrotic lesions (15 dpi) under natural infections in the field. Leaf extract analyses enabled identification of 47 metabolites belonging primary metabolism including 6 amino acids 1...
The application of plant tissue culture in cosmetics is gaining a new impetus the last few decades and it anticipated that cosmetic industries coming years will rise to an annual turnover hundred billion US dollars. Here, we focused on Linum usitatissimum (L.) well-known for its potent properties. Following their establishments from 3 distinct initial explant origins (root, hypocotyl cotyledon) selection optimal hormonal concentrations, 2 vitro systems (callus vs cell suspensions) were...
The introduction of irrigation in vineyards the Mediterranean basin is a matter debate, particular those Douro Demarcated Region (DDR), due to limited number available studies. Here, we aimed perform robust analysis three consecutive vintages (2018, 2019, and 2020) on impact deficit yield, berry quality traits, metabolome cv. 'Touriga Nacional'. Results showed that peaks extreme drought, at 30% crop evapotranspiration (ETc) (R30) was able prevent decay up 0.4 MPa leaf predawn water potential...
In vitro cultures of scarlet flax (Linum grandiflorum L.), an important ornamental flax, have been established as a new possible valuable resource lignans and neolignans for antioxidant anti-inflammatory applications. The callogenic potential at different concentrations α-naphthalene acetic acid (NAA) thidiazuron (TDZ), alone or in combinations, was evaluated using both L. hypocotyl cotyledon explants. A higher callus induction frequency observed on NAA than TDZ, especially explants, with...
Grape seed residues represent the raw material to produce several value-added products including polyphenol-rich extracts with nutritional and health attributes. Although impact of variety environmental conditions on polyphenol composition in fresh berries is recognized, no data are available regarding grape residues. The chemical from wine distilleries France, Spain Italy was characterized by mass spectrometry. Forty-two metabolites were identified belonging non-galloylated galloylated...
Trihydroxycinnamoyl spermidines (THCSpd) are plant specialized metabolites with promising pharmacological activities as antifungals, antibacterial, antiviral, and antidepressant drugs. However, their characterization potential pharmaceutical exploitation greatly impaired by the sourcing of these compounds, restricted to pollen core Eudicot species. In this work, we developed a precursor-directed biosynthesis THCSpd in yeast using dual enzymatic system based on 4-coumarate-CoA ligases (4CL)...
Grape canes are viticulture byproducts representing a sustainable source of valuable bioactive polyphenols. However, varietal origin and postharvest treatment greatly influence the effective concentration biomolecules, thus limiting industrial development. With aim to develop grape cane extracts with high polyphenol contents, selection specific variety combined optimized is major determinant. A previously described comprising cutting grapevine stalks 0.5 cm length storage at 15–20 °C over 2...
Abstract Ommochromes are widespread pigments that mediate multiple functions in invertebrates. The two main families of ommochromes ommatins and ommins, which both originate from the kynurenine pathway but differ their backbone, thereby coloration function. Despite its broad significance, how structural diversity arises vivo has remained an open question since first description. In this study, we combined organic synthesis, analytical chemistry organelle purification to address issue. From a...
ADVERTISEMENT RETURN TO ISSUEPREVCorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Postharvest Treatment of Wood Biomass from Large Collection European Grape Varieties: Impact for the Selection Polyphenol-Rich Byproducts"Kévin BilletKévin BilletEA 2106 "Biomolécules et Biotechnologie Végétales", Faculté des Sciences Pharmaceutiques, Université de Tours, F37200 FranceMore by Kévin Billet, Marianne UnlubayirMarianne UnlubayirEA Unlubayir, Thibaut MunschThibaut MunschEA...