A5060288078- Plant-Microbe Interactions and Immunity
- Plant Stress Responses and Tolerance
- Cancer therapeutics and mechanisms
- Bioactive Compounds and Antitumor Agents
- Synthesis and bioactivity of alkaloids
- Plant Pathogenic Bacteria Studies
- Mycorrhizal Fungi and Plant Interactions
- Parasitic Diseases Research and Treatment
- Computational Drug Discovery Methods
- Glutathione Transferases and Polymorphisms
- Forest Ecology and Biodiversity Studies
- Nicotinic Acetylcholine Receptors Study
- Plant Gene Expression Analysis
- Parasites and Host Interactions
- Ecology and Vegetation Dynamics Studies
- Insect symbiosis and bacterial influences
- Nematode management and characterization studies
- Yeasts and Rust Fungi Studies
- Leptospirosis research and findings
- Tuberculosis Research and Epidemiology
- Plant and Biological Electrophysiology Studies
- Legume Nitrogen Fixing Symbiosis
- Berberine and alkaloids research
- Genomics and Phylogenetic Studies
- Metabolomics and Mass Spectrometry Studies
University of Rwanda
2018-2022
Zhejiang University
2015-2018
Summary The arbuscular mycorrhizal (AM) fungi are a globally distributed group of soil organisms that play critical roles in ecosystem function. However, the ecological niches individual AM fungal taxa poorly understood. We collected > 300 samples from natural ecosystems worldwide and modelled realised virtual (VT; approximately species‐level phylogroups). found environmental spatial variables jointly explained VT distribution worldwide, with temperature pH being most important abiotic...
Calmodulin-binding transcription activator (CAMTA) constitutes one of the most important Ca2+/CaM-regulated factor families in plants. Nevertheless, phylogeny, protein interaction network and role nonhost resistance plant CAMTAs are not well understood. In this study, 200 CAMTA genes were identified from 35 species representing four major lineages. The conserved multicellular land plants but absent unicellular eukaryotes, likely to emerge fusion two separate encoding a CAMTA-like an IQ/CaM...
Cyclic nucleotide-gated ion channels (CNGCs) are calcium-permeable that involved in various biological functions. Nevertheless, phylogeny and function of plant CNGCs not well understood. In this study, 333 CNGC genes from 15 species were identified using comprehensive bioinformatics approaches. Extensive analyses demonstrated Group IVa distinct to those other groups gene structure amino acid sequence cyclic nucleotide-binding domain. A CNGC-specific motif recognizes all was generated....
Calcium and calmodulin-dependent protein kinase (CCaMK) is a member of calcium/calmodulin-dependent superfamily essential to microbe- plant symbiosis. To date, the distribution CCaMK gene in plants has not yet been completely understood, its function disease resistance remains unclear. In this study, we systemically identified genes genomes 44 species Phytozome analyzed tomato (SlCCaMK) various pathogens. CCaMKs 18 additional were identified, absence green algae cruciferous was confirmed....
Glutathione S-transferases (GSTs) constitute a superfamily of enzymes involved in detoxification noxious compounds and protection against oxidative damage. GST class Phi (GSTF), one the important classes plant GSTs, has long been considered as specific but was recently found basidiomycete fungi. However, range nonplant taxonomic groups containing GSTFs remains unknown. In this study, distribution phylogenetic relationships were investigated. We identified ascomycete fungi, myxobacteria,...
Imperative need exists to search for new anti-TB drugs that are safer, and more effective against drug-resistant strains. Medicinal plants have been the source of active ingredients drug development. However, slow growth biosafety level requirements M. tuberculosis culture considerable challenges. smegmatis can be used as a surrogate tuberculosis. In current study, preliminary phytochemical screening antimycobacterial activity evaluation crude methanolic extracts medicinal smegmatis, two...
Onchocerciasis is a severely debilitating yet neglected tropical disease (NTD) that creates social stigma, generates and perpetuates poverty, leads ultimately in some cases to irreversible unilateral or bilateral blindness if untreated. Consequently, the major impediment socioeconomic development. Many control programs have been launched for with moderate successes achieved. This mitigated hit partially due lingering need reliable, non-invasive easily applicable tools mapping endemic regions...
Phenazines are secondary metabolites with broad spectrum antibiotic activity and thus show high potential in biological control of pathogens. In this study, we identified phenazine biosynthesis (phz) genes two genome-completed plant pathogenic bacteria Pseudomonas syringae pv. tomato (Pst) DC3000 Xanthomonas oryzae (Xoo) PXO99A. Unlike the phz typical phenazine-producing pseudomonads, homologs Pst Xoo PXO99A consisted phzC/D/E/F/G phzC/E1/E2/F/G, respectively, both were not organized into an...
Objective To analyze the enzymatic properties of alkyl hydroperoxide reductase subunit C (AhpC) from Leptospira interrogans (L.interrogans) and to elucidate its physiological roles in host-pathogen interactions macrophages during infection. Methods A prokaryotic expression system for ahpC gene L. serogroup Icterohaemorrhagiae serovar Lai strain was established express recombinant AhpC (rAhpC). After purified by Ni-NTA affinity chromatography, activity rAhpC role protecting DNA...