- Global Maternal and Child Health
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Malaria Research and Control
- Mosquito-borne diseases and control
- Drug-Induced Hepatotoxicity and Protection
- Child Nutrition and Water Access
- Vector-borne infectious diseases
- Liver Disease and Transplantation
- Blood Coagulation and Thrombosis Mechanisms
- Heart Failure Treatment and Management
- Venous Thromboembolism Diagnosis and Management
- Parasitic Diseases Research and Treatment
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Pregnancy and preeclampsia studies
- Diabetes and associated disorders
- Antibiotic Use and Resistance
- COVID-19 Clinical Research Studies
- Cardiovascular Effects of Exercise
- Pulmonary Hypertension Research and Treatments
- SARS-CoV-2 and COVID-19 Research
- Congenital Heart Disease Studies
- Pancreatic function and diabetes
- Platelet Disorders and Treatments
UCLouvain
2015-2024
Institut Scientifique de Santé Publique
2022-2023
Cliniques Universitaires Saint-Luc
2001-2022
Institut Universitaire de Recherche Clinique
2022
Corvid Technologies (United States)
2022
University of Kinshasa
2021
University of Florida
2018
Centre Hospitalier Universitaire de Reims
2016
Université de Reims Champagne-Ardenne
2016
Hôpital Saint-Antoine
1999-2015
After more than a decade of community-directed treatment with ivermectin (CDTI) in Centre and Littoral Regions Cameroon, onchocerciasis endemicity was still high some communities according to the 2011 epidemiological evaluations. Some corrective measures were undertaken improve CDTI process therefore reduce burden disease. The objective present study assess progress made towards elimination 1 2 projects where worst performances found 2011. To this end, cross-sectional survey conducted April...
Physical exercise therapy is of proven efficacy in the treatment adults with depression, but corresponding evidence lacking depressed adolescent inpatients. The aim this study was to document effect add-on structured physical a clinical population adolescents hospitalized for depression and anxiety psychiatric hospital.A group 52 inpatients randomly assigned or control program three four times per week over six-week period (20 hours total). primary outcome Hospital Anxiety Depression Scale...
BackgroundSARS-CoV-2 targets endothelial cells through the angiotensin-converting enzyme 2 receptor. The resulting injury induces widespread thrombosis and microangiopathy. Nevertheless, early specific markers of dysfunction vascular redox status in COVID-19 patients are currently missing.MethodsObservational study including ICU non-ICU adult admitted hospital for acute respiratory failure, compared with control subjects matched cardiovascular risk factors similar to patients, septic shock...
This study assessed the minimum dose of clonidine required to prolong duration both anesthesia and analgesia after axillary brachial plexus blockade. Eighty patients scheduled for elective hand surgery were divided into eight groups in a randomized, double-blind fashion. An block was performed with 40 mL 1% mepivacaine plus 1:200,000 epinephrine. The control group received no clonidine. In other groups, increasing doses (0.1, 0.2, 0.3, 0.4, 0.5, 1, 1.5 micrograms/kg) added local anesthetic...
The global burden of onchocerciasis is the heaviest in sub-Saharan Africa. Studies have shown importance role Community-Directed Distributors (CDDs) and nurses control, but little known about their experience implementing control programmes. Our aim was to document barriers that CDDs local health administrators face activities.We conducted a qualitative survey consisting 16 in-depth interviews 8 focus group discussions (FGDs) across three districts Cameroon. We interviewed total 9 officials...
Recent studies in Cameroon after 20 years of implementation the Community Directed Treatment with ivermectin (CDTI) strategy, revealed mixed results as regards community ownership. This brings into question feasibility Interventions (CDI) country. We carried out qualitative surveys 3 health districts Cameroon, consisting 11 individual interviews and 10 Focus Group Discussions (FGDs) specific members. The main topic discussed during FGDs was about participation health. found an gap CDTI...
How can the decision process for fertility preservation (FP) in adolescents and prepubertal boys be improved based on patient parent feelings about FP counseling? The content of information given to patients parents hope future parenthood appeared positively impact preserve pediatric population and, therefore, deserves special attention improve care. A vast body literature adult cancer shows that reproductive capacity is a major quality-of-life issue. Patients also have strong desire...
Background Impaired cognition is a major predisposing factor for postoperative delirium, but it not systematically assessed. Anesthesia and surgery may cause delirium by affecting brain integrity. Neurofilament light in serum reflects axonal injury. Studies evaluating the perioperative course of neurofilament cardiac have shown conflicting results. The authors hypothesized that values would be higher delirious patients, baseline concentrations correlated with patients’ cognitive status...
PURPOSE: To compare predictors of infarct growth in hyperacute stroke from a retrospective review various relative and quantitative parameters calculated at perfusion-weighted magnetic resonance (MR) imaging performed within 6 hours after ictus. MATERIALS AND METHODS: Fluid-attenuated inversion recovery diffusion- images were obtained 66 patients. The initial was delineated on diffusion-weighted images; the hemodynamic disturbance, apparent mean transit time (MTT) maps; final infarct,...
Prothrombin time (PT) is a universal indicator of liver disease severity. However, variability in thromboplastin reagents leads to large interlaboratory differences PT results. The aim this study was determine whether the use international normalized ratio (INR) or other modes expression might achieve standardization patients with failure. measured seven different sensitivities plasmas from 27 miscellaneous chronic and acute failure and, as control population, 29 on oral anticoagulation...
This study assessed the minimum dose of clonidine required to prolong duration both anesthesia and analgesia after axillary brachial plexus blockade.Eighty patients scheduled for elective hand surgery were divided into eight groups in a randomized, double-blind fashion. An block was performed with 40 mL 1% mepivacaine plus 1:200,000 epinephrine. The control group received no clonidine. In other groups, increasing doses (0.1, 0.2, 0.3, 0.4, 0.5, 1, 1.5 micro g/kg) added local anesthetic...
Prothrombin time (PT) is a universal indicator of liver disease severity. However, variability in thromboplastin reagents leads to large interlaboratory differences PT results. The aim this study was determine whether the use international normalized ratio (INR) or other modes expression might achieve standardization patients with failure. measured seven different sensitivities plasmas from 27 miscellaneous chronic and acute failure and, as control population, 29 on oral anticoagulation...
The purpose of this study was to evaluate in mice the anticonvulsant potential N-palmitoylethanolamide, a putative endocannabinoid that accumulates body during inflammatory processes.N-palmitoylethanolamide injected intraperitoneally (i.p.) and evaluated for activity [in maximal electroshock seizure (MES) chemical-induced convulsions] neurologic impairment (rotorod). It compared with anandamide different palmitic acid analogues as well reference anticonvulsants (AEDs) under same...
International Normalized Ratio (INR), which standardizes prothrombin time (PT) during oral anticoagulation, has been extended to standardize PT in liver diseases and is included prognostic models such as the Model for End stage Liver Disease (MELD). However, mechanisms of prolongation differ from those involved thromboplastin reagents their sensitivities these 2 mechanisms. Our aim was determine whether, calibration model thromboplastins proposed by World Health Organization, use plasmas...