A5030607028- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Orthopaedic implants and arthroplasty
- Cardiac Structural Anomalies and Repair
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Particle Detector Development and Performance
- Cardiomyopathy and Myosin Studies
- CCD and CMOS Imaging Sensors
- Hemodynamic Monitoring and Therapy
- Cardiac electrophysiology and arrhythmias
- Graph theory and applications
- Radiation Detection and Scintillator Technologies
- History and advancements in chemistry
- Cardiac Arrhythmias and Treatments
- Cardiovascular and exercise physiology
- Computational Drug Discovery Methods
- Cardiovascular Effects of Exercise
- Cardiac pacing and defibrillation studies
- Advanced Graph Theory Research
- Venous Thromboembolism Diagnosis and Management
University of Glasgow
2006-2025
University of British Columbia
2024-2025
Queen Elizabeth University Hospital
2016-2024
University of St Andrews
2024
American Medical Group Association
2019-2021
DMG Mori (Japan)
2019
Ipsos (Brazil)
2019
Geisinger Medical Center
2010-2016
Southern General Hospital
2015
Western Infirmary
2013-2014
Two hundred fifty patients were enrolled in a multicenter, community-based study of the efficacy intracoronary streptokinase thrombolysis acute myocardial infarction; 134 randomly assigned to therapy and 116 controls. All underwent left ventricular angiography coronary arteriography before random assignment. The mean time from onset symptoms hospitalizaron was 134±144 minutes (S.D), assignment 276±185 minutes. Coronary reperfusion achieved 68 per cent streptokinase-treated group. overall...
to complement, not replace, sound medical judgment and knowledge.They are intended for operators who possess the cognitive technical skills performing PCI assume that facilities resources required properly perform available.As in past, indications categorized as Class I, II, or III based on a multifactorial assessment of risk well expected efficacy viewed context current knowledge relative strength this knowledge.Initially, document describes background information forms foundation specific...
To determine to what extent the diagnostic accuracy of stress testing is influenced by prevalence coronary-artery disease, we correlated description chest pain, result and results coronary arteriography in 1465 men 580 women from a multicentered clinical trial. The pre-test risk (prevalence disease) varied 7 87 per cent, depending on sex classification pain. A positive test increased only 6 20 whereas negative decreased 2 28 cent. Aothough percentage false-positive differed between (12 +/- 1...
The prevalence of coronary artery stenoses greater than or equal to 70% left main stenosis 50% was evaluated in 20,391 patients who underwent angiography the Coronary Artery Surgery Study from 1975-1979. After with unstable angina myocardial infarction were excluded, disease 8157 definite angina, probable and nonspecific chest pain 93%, 66% 14% men 72%, 36% 6% women (p less 0.001). age sex character important determinants severity. Left three-vessel occurred more middle-aged older had 60...
To identify predictors of long-term outcome after balloon aortic valvuloplasty, we analyzed data on 674 adults (mean age, 78 +/- 9 years; 56% were women) undergoing this procedure at 24 clinical centers who had a mean initial increase in valve area 0.3 cm2.Baseline included clinical, echocardiographic, and catheterization variables. Follow-up mortality, cause death, rehospitalization, 6-month echocardiography, functional status. Kaplan-Meier curves log-rank tests used to evaluate survival...
Fifteen institutions participating in the Collaborative Study Coronary Artery Surgery (CASS) have performed isolated coronary artery bypass surgery upon 6630 patients (1061 women and 5569 men) for disease. The overall operative mortality (OM) was 2.3% (range 0.3-6.4%). Mortality increased with age, from 0 group 20-29 years old to 7.9% 70 older. OM higher each group, ranging 2.8% ages 30-39 12.3% age older (0.8% 5.8% men). Clinical manifestations of congestive heart failure were associated...
Data were collected prospectively on 7553 consecutive patients undergoing coronary arteriography. The studies performed at 13 clinics of the Collaborative Study Coronary Artery Surgery (CASS) using brachial and femoral techniques. There eight deaths 0--24 hours seven 24--48 after arteriography (2/1000). 15 non-fatal myocardial infarctions (MIs) four MIs (2.5/1000). Of 657 cases with left main stenosis greater than or equal to 50%, five died three had MI. Left disease increased risk death by...
Eight hundred seventy arteriograms from the Coronary Artery Surgery Study (CASS) were independently read by readers at two different clinics to evaluate reproducibility of interpretation coronary arteriograms. Among proximal segments, lesions left main artery least reproducible, P less than .02. When one angiographer reads a stenosis 50% or more in artery, it is estimated that second reader will report no lesion 18.6% time. In 94.7% films, number significantly (greater equal 70% stenosis)...
Thrombolytic recanalization of the obstructed coronary lumen was studied in 32 patients receiving intracoronary streptokinase for 60 to 90 min during acute myocardial infarction. The process viewed at high arteriographic magnification and quantified with computer-assisted measurements from repeated single-plane views. variability method this application 0.15 0.18 mm on minimum diameter estimates. Structural details were seen that are not commonly appreciated conventional magnification....
Three hundred sixty-eight patients were randomly assigned to receive intravenous streptokinase (IVSK) (n = 191) or standard therapy 177) determine the efficacy of IVSK in treatment acute myocardial infarction. The mean time was 3.5 hr. At 14 days there 12 deaths group (6.3%) and 17 control (9.6%) (p .23). Early mortality related infarct location. Fourteen day for anterior infarctions 10.4% with 22.4% .06) similar IVSK-treated inferior infarctions, 4.0% vs 1.8% .32). For those randomized...