A5035731447- Neurobiology and Insect Physiology Research
- Retinal Development and Disorders
- Olfactory and Sensory Function Studies
- Visual perception and processing mechanisms
- Insect Pheromone Research and Control
- CRISPR and Genetic Engineering
- Plant Reproductive Biology
- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
- Advanced Fluorescence Microscopy Techniques
- Receptor Mechanisms and Signaling
- Physiological and biochemical adaptations
Stanford University
2016-2024
Harvard University
2023
The evolutionary expansion of sensory neuron populations detecting important environmental cues is widespread, but functionally enigmatic. We investigated this phenomenon through comparison homologous olfactory pathways Drosophila melanogaster and its close relative sechellia, an extreme specialist for Morinda citrifolia noni fruit. D. sechellia has evolved species-specific expansions in select, noni-detecting (OSN) populations, multigenic changes. Activation inhibition defined proportions...
The evolutionary expansion of sensory neuron populations detecting important environmental cues is widespread, but functionally enigmatic. We investigated this phenomenon through comparison homologous neural pathways
Abstract Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene to specific fractions a genetically-defined cell-type is challenging. We developed S parse P redictive A ctivity through R ecombinase C ompetition (SPARC), generalizable toolkit that can express any effector precise proportions post-mitotic Drosophila . Using this approach, we demonstrate targeted many effectors and apply...