A5080907776- Wastewater Treatment and Nitrogen Removal
- Cell death mechanisms and regulation
- Mitochondrial Function and Pathology
- Carbon and Quantum Dots Applications
- Pharmaceutical and Antibiotic Environmental Impacts
- Heavy metals in environment
- Redox biology and oxidative stress
- ATP Synthase and ATPases Research
- Water Treatment and Disinfection
- Ammonia Synthesis and Nitrogen Reduction
- Lipid Membrane Structure and Behavior
- Aquatic Ecosystems and Phytoplankton Dynamics
- Inflammasome and immune disorders
- Nanocluster Synthesis and Applications
- bioluminescence and chemiluminescence research
- Photosynthetic Processes and Mechanisms
- Alzheimer's disease research and treatments
- Nanoparticles: synthesis and applications
- Mine drainage and remediation techniques
- Microbial Fuel Cells and Bioremediation
- Electron Spin Resonance Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Luminescence and Fluorescent Materials
- Heavy Metal Exposure and Toxicity
- Constructed Wetlands for Wastewater Treatment
Guiyang Medical University
2022-2025
Kunming Medical University
2017-2025
Beihang University
2019-2024
Guangdong Provincial People's Hospital
2024
Yueyang Hospital
2024
Shanghai University of Traditional Chinese Medicine
2024
Shanghai Electric (China)
2024
Jiangsu Cancer Hospital
2024
Nanjing Medical University
2024
Union Hospital
2023
Extracellular polymeric substances (EPS) of microbial sludge play a crucial role in removal organic micropollutants during biological wastewater treatment. In this study, we examined ciprofloxacin (CIP) three parallel bench-scale reactors using aerobic (AS), anaerobic (AnS), and sulfate-reducing bacteria (SRB) sludge. The results showed that the SRB had highest specific CIP rate via adsorption biodegradation. by EPS accounted up to 35. 6 ± 1.4%, 23.7 0.6%, 25.5 0.4% total AS, AnS, systems,...
Abstract Objective Enhanced lipid peroxidation is well established in traumatic brain injury. However, its molecular targets, identity of peroxidized phospholipid species, and their signaling role have not been deciphered. Methods Using controlled cortical impact as a model injury, we employed newly developed oxidative lipidomics approach to qualitatively quantitatively characterize the response. Results Electrospray ionization matrix‐assisted laser desorption/ionization mass spectrometry...
Microcystin-producing Microcystis bloom is a severe water problem in the world. Some reports indicate that chronic exposure to microcystin may result liver damage adults, but information on effects children limited.We investigated relationship between and children.We measured concentrations drinking aquatic food (carp duck) from two lakes four wells. Participants were 1,322 7-15 years of age who obtained one tested sources, completed questionnaires, provided blood samples for serum enzymes...
Abstract Carbon quantum dots (CQDs) were synthesized by heating various carbon sources in HNO 3 solution at reflux, and the effects of concentration on size CQDs investigated. Furthermore, oxygen‐containing surface groups as‐prepared selectively reduced NaBH 4 , leading to new states. The experimental results show that sizes can be tuned then influence their photoluminescent behaviors; properties are related both state CQDs, but photocatalytic activities determined states alone. different...
Damage of presynaptic mitochondria could result in release proapoptotic factors that threaten the integrity entire neuron. We discovered α-synuclein (Syn) forms a triple complex with anionic lipids (such as cardiolipin) and cytochrome c, which exerts peroxidase activity. The latter catalyzes covalent hetero-oligomerization Syn c into high molecular weight aggregates. is preferred substrate this reaction oxidized more readily than cardiolipin, dopamine, other phenolic substrates....
The molecular diversity of phospholipids is essential for their structural and signaling functions in cell membranes. In the current work, we present, results mass spectrometric characterization individual species major classes -- phosphatidylcholine (PtdCho), phosphatidylethanolamine (PtdEtn), phosphatidylserine (PtdSer), phosphatidylinositol (PtdIns), sphingomyelin (CerPCho), cardiolipin (Ptd(2)Gro) oxidation products during apoptosis induced neurons by staurosporine (STS). rat cortical...
Jiang, J., Stoyanovsky, D. A., Belikova, N. Tyurina, Y. Y., Zhao, Q., Tungekar, M. Kapralova, V., Huang, Z., Mintz, A. H., Greenberger, J. S. and Kagan, V. E. A Mitochondria-Targeted Triphenylphosphonium-Conjugated Nitroxide Functions as a Radioprotector/Mitigator.Removal of excessive mitochondrial reactive oxygen species by electron scavengers antioxidants is promising therapeutic strategy to reduce the detrimental effects radiation exposure. Here we exploited triphenylphosphonium (TPP)...
Plasma is generated by ionizing gas molecules. Helium (He)-based cold atmospheric plasma (CAP) was using a high-voltage power supply with low-frequency excitation (60 Hz at 7 kV) and He flow 2 l/min. Platinum nanoparticles (Pt-NPs) are potent antioxidants due to their unique ability scavenge superoxides peroxides. These features make them useful for the protection against oxidative stress-associated pathologies. Here, effects of Pt-NPs on He-CAP-induced apoptosis underlying mechanism were...
Microglia M1 polarization plays important role in the development of ischemic stroke (IS). This study explored transcription factor 7 like 2 (TCF7L2) regulating microglia during IS. TTC staining was used to determine cerebral infarction, and Nissl applied examine neuronal injury. The secretion levels cytokines were measured using ELISA. interaction between Zinc finger E-Box binding homeobox (ZEB2) TCF7L2 analyzed by Co-IP, H3K27ac enrichment promoter detected ChIP assay. knockdown reduced...
This study investigated the role of integrin-linked kinase (ILK) in neuronal apoptosis induced by cerebral ischemia‒reperfusion injury (CIRI) and its interaction with a circRNA (0000964) miR-758-3p. Using vivo vitro rat models, we clarified how ILK regulates during CIRI. Our findings revealed that expression is upregulated response to CIRI modulated (0000964)/miR-758-3p axis. provides new insights into molecular mechanisms suggests potential therapeutic targets reduce apoptosis. A model was...
Suppression of mitochondrial production reactive oxygen species is a promising strategy against intrinsic apoptosis typical degenerative diseases. Stable nitroxide radicals such as 4-hydroxy-2,2,6,6-tetramethyl piperidine-1-oxyl (TEMPOL) and its analogs combine several important features, including recycleability, electron acceptance from respiratory complexes, superoxide dismutase mimicry, radical scavenging. Although successful in antioxidant protection, their effective concentrations are...