- Anatomy and Medical Technology
- Facial Trauma and Fracture Management
- Bone Tissue Engineering Materials
- Surgical Simulation and Training
- Dental Radiography and Imaging
- Dental Implant Techniques and Outcomes
- Additive Manufacturing and 3D Printing Technologies
- Dental materials and restorations
- Craniofacial Disorders and Treatments
- Orthopedic Surgery and Rehabilitation
- Digital Imaging in Medicine
- 3D Printing in Biomedical Research
- Gastric Cancer Management and Outcomes
- Cleft Lip and Palate Research
- Colorectal Cancer Screening and Detection
- Traumatic Ocular and Foreign Body Injuries
- Orthodontics and Dentofacial Orthopedics
- Dental Research and COVID-19
- Reconstructive Surgery and Microvascular Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Bone fractures and treatments
- Colorectal Cancer Surgical Treatments
- Esophageal Cancer Research and Treatment
- Electrospun Nanofibers in Biomedical Applications
- Spinal Fractures and Fixation Techniques
University of Basel
2015-2025
University Hospital of Basel
2016-2025
Johannes Gutenberg University Mainz
2017-2023
University Medical Center of the Johannes Gutenberg University Mainz
2017-2023
Hospital Leforte
2019-2023
Universidade Metodista de São Paulo
2023
NYU Langone Health
2022
Massachusetts General Hospital
2022
Harvard University
2022
Marymount University
2021
Additive manufacturing (AM) is rapidly gaining acceptance in the healthcare sector. Three-dimensional (3D) virtual surgical planning, fabrication of anatomical models, and patient-specific implants (PSI) are well-established processes fields. Polyetheretherketone (PEEK) has been used, mainly reconstructive surgeries as a reliable alternative to other alloplastic materials for PSI. Recently, it become possible fabricate PEEK PSI with Fused Filament Fabrication (FFF) technology. 3D printing...
With the rapid progression of additive manufacturing and emergence new 3D printing technologies, accuracy assessment is mostly being performed on isosymmetric test bodies. However, anatomic models can vary. The dimensional root mean square values in terms trueness precision 50 mandible replicas, printed with five common were evaluated. highest was found for selective laser sintering printer (0.11 ± 0.016 mm), followed by a binder jetting (0.14 0.02 fused filament fabrication (0.16 0.009 mm)....
Abstract Introduction The aim of this study was to evaluate whether inexpensive 3D models can be suitable train surgical skills dental students or oral and maxillofacial surgery residents. Furthermore, we wanted know which the most common filament materials, acrylonitrile butadiene styrene ( ABS ) polylactic acid PLA ), better simulate human bone according surgeons' subjective perceptions. Materials Methods Upper lower jaw were produced with desktop printers, silicon rubber for soft tissue...
Polyetheretherketone (PEEK) is a prime candidate to replace metallic implants and prostheses in orthopedic, spine cranio-maxillofacial surgeries. Fused-filament fabrication (FFF) an economical efficient three-dimensional (3D) printing method fabricate PEEK implants. However, studies pertaining the bioactivity of FFF 3D printed are still lacking. In this study, samples were fabricated modified with polishing grit-blasting (three alumina sizes: 50, 120, 250 µm) achieve varying levels surface...
Computer-assisted surgery with three-dimensional (3D) printed surgical guides provides more accurate results than free-hand surgery. Steam sterilization could be one of the factors that affect dimensions guide resin materials, leading to inaccuracies during surgeries. The purpose this study was evaluate effects steam on dimensional accuracy indication-specific hollow cube test bodies, manufactured in-house using Class IIa biocompatible materials (proprietary and third-party). To pre-...
Recent advancements in medical imaging, virtual surgical planning (VSP), and three-dimensional (3D) printing have potentially changed how today’s craniomaxillofacial surgeons use patient information for customized treatments. Over the years, polyetheretherketone (PEEK) has emerged as biomaterial of choice to reconstruct craniofacial defects. With additive manufacturing (AM) systems, prospects point-of-care (POC) 3D PEEK patient-specific implants (PSIs) emerged. Consequently, investigating...
The most common three-dimensional (3D) printing method is material extrusion, where a pre-made filament deposited layer-by-layer. In recent years, low-cost polycaprolactone (PCL) has increasingly been used in 3D printing, exhibiting sufficiently high quality for consideration cranio-maxillofacial reconstructions. To increase osteoconductivity, prefabricated filaments bone repair based on PCL can be supplemented with hydroxyapatite (HA). However, few reports PCL/HA composite extrusion...
This in-vitro study compared the accuracy of implant placement using static versus dynamic computer-assisted surgery (CAIS) at two sites.Partially edentulous maxillary models were 3D-printed, and implants (Straumann TL RN 4.1 × 10 mm) inserted in FDI positions 15 16 per model CAIS approaches (10 approach). A three-dimensional (3D) reconstruction tool was used for planning, surgical guide design, measuring positioning accuracy. In CAIS, placed with 3D-printed guides (n = 20); real-time...
Recently, three-dimensional (3D) printing has become increasingly popular in the medical sector for production of anatomical biomodels, surgical guides, and prosthetics. With availability low-cost desktop 3D printers affordable materials, in-house or point-of-care manufacturing biomodels Class II devices gained considerable attention personalized medicine. Another projected development treatment is patient-specific implants (PSIs) partial total bone replacements made medical-grade material...
Reconstruction of cranial defects is an arduous task for craniomaxillofacial surgeons. Additive manufacturing (AM) or three-dimensional (3D) printing titanium patient-specific implants (PSIs) made its way into cranioplasty, improving the clinical outcomes in complex surgical procedures. There has been a significant interest within medical community redesigning based on natural analogies. This paper proposes workflow to create biomimetic prosthesis with interconnected strut macrostructure...
The objective of this study was to determine the effect two plasma surface treatments on biologic responses PEEK medical implants manufactured by fused filament fabrication (FFF) 3D printing technology.This created standard samples using an FFF printer. After fabrication, half were polished simulate a smooth surface. Then, argon (Ar) or oxygen (O2) used modify bioactivity printed and samples. Scanning electron microscopy (SEM) profilometer microstructure roughness sample surfaces....
Additive manufacturing (AM) of polyetheretherketone (PEEK) biomaterials using the material-extrusion (MEX) method has been studied for years. Because challenging process, precisely controlling printing parameters is crucial. This study aimed to investigate effects such as orientation and position on mechanical properties. Thus, 34 samples were printed PEEK filament MEX process. Samples divided into two main groups (A,B) according their orientations (A: 1–3) positions build plate (B: 4–8)....
Polyetheretherketone (PEEK), a biomaterial with appropriate bone-like mechanical properties and excellent biocompatibility, is widely applied in cranio-maxillofacial dental applications. However, the lack of antibacterial effect an essential drawback PEEK material might lead to infection osseointegration issues. This study aims apply natural agent, totarol coating onto 3D printed surface find optimized concentration balanced cytocompatibility, osteogenesis, capability.
Abstract Background Bioresorbable patient-specific additive-manufactured bone grafts, meshes, and plates are emerging as a promising alternative that can overcome the challenges associated with conventional off-the-shelf implants. The fabrication of implants (PSIs) directly at point-of-care (POC), such hospitals, clinics, surgical centers, allows for more flexible, faster, efficient processes, reducing need outsourcing to external manufacturers. We want emphasize potential advantages...
OBJECT The authors describe a novel technique using computer-assisted design (CAD) and computed-assisted manufacturing (CAM) for the fabrication of individualized 3D printed surgical templates frontoorbital advancement surgery. METHODS Two patients underwent surgery unilateral coronal synostosis. Virtual planning (SurgiCase-CMF, version 5.0, Materialise) was done by virtual mirroring techniques superposition an age-matched normative pediatric skull model. Based on these measurements, were...
Summary: Craniofacial defects often result in aesthetic and functional deficits, which affect the patient’s psyche wellbeing. Patient-specific implants remain optimal solution, but their use is limited or impractical due to high costs. This article describes a fast cost-efficient workflow of in-house manufactured patient-specific for craniofacial reconstruction cranioplasty. As proof concept, we present case defect with involvement supraorbital rim. The following hybrid manufacturing process...
Additive manufacturing (AM) of patient-specific implants (PSIs) is gradually moving towards in-house or point-of-care (POC) manufacturing. Polyetheretherketone (PEEK) has been used in cranioplasty cases as a reliable alternative to other alloplastic materials. As only few fused filament fabrication (FFF) printers are suitable for manufacturing, the quality characteristics fabricated by FFF technology still under investigated. This paper aimed investigate PEEK PSIs craniofacial...
The use of patient-specific implants (PSIs) in craniofacial surgery is often limited due to a lack expertise and/or production costs. Therefore, simple and cost-efficient template-based fabrication workflow has been developed overcome these disadvantages. aim this study assess the accuracy PSIs made from their original templates. For representative cranial defect (CRD) temporo-orbital (TOD), ten were polymethylmethacrylate (PMMA) using computer-aided design (CAD) three-dimensional (3D)...
The aim of this study was to compare the efficacy intraoperative bending titanium mesh with pre-contoured “hybrid” patient-specific for surgical repair isolated orbital floor fractures. In-house 3D-printed anatomical models were used as guides. main outcome measures preoperative and postoperative volume surgery time. We performed a retrospective cohort including 22 patients who had undergone between May 2016 November 2018. first twelve underwent conventional reconstruction free-hand an...
Recent advances in 3D printing technology have enabled the emergence of new educational and clinical tools for medical professionals. This study provides an exemplary description fabrication 3D-printed individualised patient models assesses their value compared to cadaveric oral maxillofacial surgery.A single-stage, controlled cohort was conducted within context a curricular course. A patient's CT scan segmented into stereolithographic model then printed using fused filament printer. These...
To develop a novel 3D-printer-assisted method to fabricate patient-specific implants for cranioplasty and demonstrate its feasibility use in 16 consecutive cases. We report on patients who have undergone surgery an extensive skull defect after decompressive which the bone flap was not available. present workflow implant production using molding technique. Preoperative, intraoperative, postoperative data were analyzed/evaluated. Eleven out of our (68.7%) presented with hemispheric defects....