A5014462176- Workplace Health and Well-being
- Forest Biomass Utilization and Management
- Eating Disorders and Behaviors
- Employment and Welfare Studies
- Radiation Detection and Scintillator Technologies
- Particle Detector Development and Performance
- Bipolar Disorder and Treatment
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Child Nutrition and Feeding Issues
- Dementia and Cognitive Impairment Research
- Regulation of Appetite and Obesity
- Autism Spectrum Disorder Research
- Child and Adolescent Psychosocial and Emotional Development
- Stress and Burnout Research
- Forest Management and Policy
- Healthcare professionals’ stress and burnout
- Tryptophan and brain disorders
- Adipose Tissue and Metabolism
- Olfactory and Sensory Function Studies
- Neurotransmitter Receptor Influence on Behavior
- Tactile and Sensory Interactions
- COVID-19 and Mental Health
- Attention Deficit Hyperactivity Disorder
- Bioenergy crop production and management
Osaka Metropolitan University
2022-2025
Tokyo Metropolitan University
2021-2025
Mie University
2024
Osaka City University
2014-2023
Nihon University
2002-2023
Toyohashi University of Technology
2023
National Institute of Technology, Asahikawa College
2023
Nagoya University
1994-2022
Chuo University
2022
Dokkyo Medical University
2022
Obesity endangers the lives of millions people worldwide, through comorbidities such as heart disease, cancers, type 2 diabetes, stroke, arthritis, and major depression. New approaches to control body weight remain a high priority. Vaccines traditionally have been used protect against infectious diseases and, more recently, for unconventional targets drug addiction. Methodologies that could specifically modulate bioavailability an endogenous molecule regulates energy balance might provide...
Although inflammatory cytokines are established biomarkers of mood disorders, their molecular mechanism is not known. We hypothesized that circulating mitochondrial DNA (mtDNA) contributes to inflammation and could be used as biomarkers. investigated if mtDNA level associated with can a biomarker disorders. Plasma concentration was measured real-time quantitative PCR targeting two regions the plasma levels four (GM-CSF, IL-2, IL-4, IL-6) were multiplex immunoassay method in 109 patients...
Attempts to understand ingestion have sought the control of meals. The present study evaluated a meal definition that included prandial drinking (drinking-explicit meals). spontaneous nocturnal intake male Wistar rats was studied. breakpoint defined as interval between feeding or events providing most stable estimate structure. Alternative breakpoints derived from prevailing methodology, log-survivorship, frequency histogram analysis interfeeding intervals without respect were compared...
We report, in this paper, that crystalline In–Ga–Zn-oxide (IGZO) can be formed over an amorphous surface or uneven by a sputtering process at lower than 500 °C through the purification of IGZO. Crystalline IGZO, which no clear grain boundary is observed, shows c -axis alignment but random - and b orientations without alignment. This crystal morphology differs from other morphologies have been known thus far, such as single polycrystal morphologies. Our model for understanding formation [...
This study aims to clarify the effect of occupational stress and changes in work environment on non-healthcare workers’ (HCWs) mental health during third wave COVID-19 pandemic Japan. A web-based, cross-sectional survey was conducted from 16 17 December 2020. Data 807 non-HCWs were included. We evaluated using Generic Job Stress Questionnaire (GJSQ). Depressive anxiety symptoms assessed Japanese version Patient Health Questionnaire-9 Generalized Anxiety Disorder 7-item scale, respectively....
Using pharmacological tools, a role for opioid receptors in the regulation of food intake has been documented. However, involvement specific receptor subtypes remains questionable, and little information is available regarding energy metabolism. adult male mice lacking μ-opioid (MOR) gene (MOR−/−), we show that MOR not essential maintenance normal levels ad libitum but does modulate efficiency storage during high-fat diets through partitioning. When fed regular diet, MOR−/− displayed only...
Diagnostic biomarkers of major depressive disorder, bipolar and schizophrenia are urgently needed, because none currently available.We performed a comprehensive metabolome analysis plasma samples from drug-free patients with disorder (n=9), (n=6), (n=17), matched healthy controls (n=19) (cohort 1) using liquid chromatography time-of-flight mass spectrometry. A significant effect diagnosis was found for 2 metabolites: nervonic acid cortisone, being the most significantly altered. The...
Corticotropin-releasing factor (CRF) has been hypothesized to modulate consummatory behavior through the Type 2 CRF (CRF(2)) receptor. However, behavioral functions subserved by CRF(2) receptor remain poorly understood. Recently, human urocortin II (hUcn II), a selective agonist, was identified. To study effects of this neuropeptide on ingestive behavior, we examined centrally infused hUcn (i.c.v. 0, 0.01, 0.1, 1.0, 10.0 micro g) microstructure nose-poke responding for food and water in...
To improve the management of depression and prevention suicide, we investigated associations between lifestyle, working environment, depressive symptoms suicidal ideation. Variables measured included job stressors, hours, overtime work, smoking status, alcohol consumption, sleep, exercise, meals, family factors. Original items were used to measure on holidays, number confidants, use stress reduction techniques, A total 4,118 employees (2,834 men, 1,284 women) in eleven cities districts...
Abstract Background Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells into the extracellular space. In nervous system, EVs have been found to help promote myelin formation, neurite growth, and neuronal survival, thus playing a role in tissue repair regeneration. Therefore, intercellular communication through is thought be involved pathogenesis of multiple central system diseases, including neuropsychiatric disorders. The fact that bloodstream from brain...
The aim of this study was to ascertain whether there has been an increase in the number workers with long-term sickness absence due mental disorders (LTSA-MD) and determine impact remote work on new LTSA-MD cases. A web-based questionnaire sent 2,552 company offices 150 or more Osaka Prefecture. Data were obtained between April 1, 2019, March 31, 2020 (fiscal year 2019) 2020, 2021 2020), along their MD diagnoses (adjustment disorder [AD], depressive [DEP], etc.). difference LTSA-MD, LTSA-AD,...
Background Over the years, occupations and workplaces have become more gender neutral as female participation in workforce has risen. However, few studies reported how composition of workplace affects occupational stress. Objective This study aims to evaluate relationship between stress among Japanese public servants. Methods cross-sectional study, conducted 2019, included 18,486 servants from City A, Japan, using data Brief Job Stress Questionnaire (BJSQ). After exclusions, 16,444...
Japanese teachers are mentally and physically burdened with various work stressors. This cross-sectional study examined the relationship between depressive symptoms perceived individual level occupational stress including role problems among schoolteachers. included 1,006 working in public schools a city. The version of Zung's Self-Rating Depression Scale (SDS) was used to evaluate symptoms, Generic Job Stress Questionnaire three measures social support. Subjects SDS scores more than 50 were...
Insomnia among workers reduces the quality of life, contributes toward economic burden healthcare costs and losses in work performance. The relationship between occupational stress insomnia has been reported previous studies, but there little attention to temperament safety health research. aim this study was clarify relationships temperament, stress, insomnia. subjects were 133 Japanese daytime local government employees. Temperament assessed using Evaluation Memphis, Pisa, Paris, San...
Long-term sickness absence (LTSA) imposes significant social and economic burdens. This study investigated how workplace factors influence the duration of LTSA for mental disorders (LTSA-MD) physical diseases (LTSA-PD), hypothesizing that LTSA-MD is more strongly associated with occupational stress than LTSA-PD. retrospective observational involved public servants from a Japanese municipality who had participated in National Stress-Check Program between 2011 2022. Participants were aged...
Two corticotropin-releasing factor (CRF) receptor families have been identified (CRF<sub>1</sub> and CRF<sub>2</sub>). Whereas anxiogenic-like roles for the CRF<sub>1</sub> identified, behavioral functions of CRF<sub>2</sub> remain obscure. Urocortin 2 (Ucn 2), a CRF-related peptide that selectively binds receptors, was recently recognized its central anorectic properties. The present study tested hypothesis anorexigenic mode action Ucn differed from ovine CRF (oCRF), preferential agonist....