A5091270080- Oral microbiology and periodontitis research
- Periodontal Regeneration and Treatments
- Probiotics and Fermented Foods
- Oral and gingival health research
- Oral Health Pathology and Treatment
- Dental Erosion and Treatment
- Microbial Community Ecology and Physiology
- Dental Health and Care Utilization
- Gut microbiota and health
- Oral and Maxillofacial Pathology
- Streptococcal Infections and Treatments
- HIV/AIDS oral health manifestations
- Bee Products Chemical Analysis
- Essential Oils and Antimicrobial Activity
- Dental Radiography and Imaging
- Immune Response and Inflammation
- Bacterial biofilms and quorum sensing
- Dental Implant Techniques and Outcomes
- Environmental and biological studies
- Natural product bioactivities and synthesis
- Salivary Gland Disorders and Functions
- Reconstructive Surgery and Microvascular Techniques
- Electrospun Nanofibers in Biomedical Applications
- Phytochemistry and Biological Activities
- Dental materials and restorations
Faculdade São Leopoldo Mandic
2024-2025
Universidade de São Paulo
2020-2024
Guarulhos University
2022
Universidade Estadual de Campinas (UNICAMP)
2017-2019
Universidade Federal de Sergipe
2017
Abstract Periodontitis is characterized by a dysbiotic microbial community and treatment strategies include the reestablishment of symbiosis reducing pathogens abundance. Aggregatibacter actinomycetemcomitans (Aa) frequently associated with rapidly progressing periodontitis. Since oral ecosystem may be affected metabolic end‐products bacteria, we evaluated effect soluble compounds released probiotic lactobacilli, known as postbiotics, on Aa biofilm expression virulence‐associated genes....
Background: Considering xenogeneic collagen matrix (CM) and enamel derivative (EMD) characteristics, it is suggested that their combination could promote superior clinical outcomes in root coverage procedures. Thus, the aim of this parallel, double‐masked, dual‐center, randomized trial to evaluate after treatment localized gingival recession (GR) by a coronally advanced flap (CAF) combined with CM and/or EMD. Methods: Sixty‐eight patients presenting one Miller Class I or II GRs were randomly...
Background: Gingival recession (GR) might be associated with patient discomfort due to cervical dentin hypersensitivity (CDH) and esthetic dissatisfaction. The aim is evaluate the effect of root coverage procedure a xenogenous collagen matrix (CM) and/or enamel derivative (EMD) in combination coronally advanced flap (CAF) on CDH, esthetics, oral health–related quality life (OHRQoL) patients GR. Methods: Sixty‐eight participants single Miller Class I/II GRs were treated CAF (n = 17), + CM EMD...
The aim of this article is to evaluate the effect different portions Platelet Rich Fibrin (PRF) membranes and liquid-PRF, prepared by two distinct protocols/centrifuges each, on multispecies subgingival biofilm. PRF liquid-PRF were using protocols: centrifuge 1 uses fixed acceleration while 2, progressive acceleration. samples introduced into device concurrently with 33-species bacterial inoculum. After seven days, biofilm metabolic activity (MA) microbial profile evaluated through...
Probiotics may be considered as an additional strategy to achieve a balanced microbiome in periodontitis. However, the mechanisms underlying use of probiotics prevention or control periodontitis are still not fully elucidated. This vitro study aimed evaluate effect two commercially available strains lactobacilli on gingival epithelial cells (GECs) challenged by Aggregatibacter actinomycetemcomitans . OBA-9 GECs were infected with A. strain JP2 at MOI 1:100 and/or co-infected Lactobacillus...
The benefits of probiotics on dysbiotic microbiomes and inflammation are dependent the tested strain, host factors, resident microbiome. There is limited knowledge effects in A. actinomycetemcomitans-associated periodontitis. Thus, Lactobacillus acidophilus LA5 (LA5) was orally inoculated for 30 days C57Bl/6 mice infected with actinomycetemcomitans JP2 (Aa) S. gordonii (Sg). Alveolar bone loss, gingival gene expression, oral gut were determined. controlled loss Aa+Sg-infected mice,...
The aim of this study was to evaluate the effect combination neovestitol–vestitol (CNV) compounds obtained from Brazilian red propolis on microbiological profile a mature multispecies subgingival biofilm. biofilm with 32 bacterial species associated periodontitis formed for seven days using Calgary device. Treatment CNV (1600, 800, 400, and 200 μg/mL), amoxicillin (54 vehicle control performed 24 h last day formation. Biofilm metabolic activity DNA–DNA hybridization (checkerboard) assays...
The isoflavone (3S)-vestitol, obtained from red propolis, has exhibited anti-inflammatory, antimicrobial, and anti-caries activity; however, few manuscripts deal with its anti-inflammatory mechanisms in macrophages. objective is to elucidate the of (3S)-vestitol on those cells. Peritoneal macrophages C57BL6 mice, stimulated lipopolysaccharide, were treated 0.37 0.59 µM for 48 h. Then, nitric oxide (NO) quantities, viability, release 20 cytokines transcription several genes related cytokine...
Periodontitis is an inflammatory disease induced by a dysbiotic oral microbiome. Probiotics of the genus Bifidobacterium may restore symbiotic microbiome and modulate immune response, leading to periodontitis control. We evaluated effect two strains able inhibit Porphyromonas gingivalis interaction with host cells biofilm formation, but distinct immunomodulatory properties, in mice model. Experimental (P+) was C57Bl/6 microbial consortium human organisms. B. bifidum 162 2A [B+ (1622)] breve...
Abstract Background This study aimed to evaluate, histomorphometrically, the use of collagen matrix (CM) and/or enamel derivative (EMD) for treatment dehiscence‐type recession defects in minipigs. Methods Eight healthy, male, young BR‐1 minipigs, with no periodontal disease were treated. Bilateral surgically created on buccal mandibular premolars (PI and PII). After 30 days, randomly assigned four groups: coronally advanced flap (CAF); CAF + CM; EMD; CM EMD (split‐mouth design). The...
Oral bacteria are implicated not only in oral diseases but also gut dysbiosis and inflammatory conditions throughout the body. The periodontal pathogen
The present study evaluated the antibiofilm effects of Lactobacillus acidophilus within a subgingival multispecies biofilm. (La5) at 1 × 10 2 , 4 and 6 were included beginning biofilm formation, which lasted 7 days. biofilms comprised 33 periodontitis-related bacterial species Calgary Biofilm device was used. At end, DNA–DNA hybridization (checkerboard) performed. A Kruskal–Wallis test followed by Dunn post hoc performed ( p ≤ 0.05). La5 reduced total counts proportions red green complexes...
Introdução: Estima-se que a incidência da síndrome de Down seja um cada 660 nascimentos. Sendo as anomalias dentárias frequentes nessa parcela população, é importante seu correto diagnóstico para o planejamento do tratamento. Objetivo: Realizar levantamento das alterações dentárias, como desenvolvimento, por meio radiografi panorâmicas. Métodos: Foram avaliadas panorâmicas realizadas em 27 pacientes com atendidos na Unidade Diagnóstico Oral e Odontologia Pessoas Especiais (UDOPE), entre...