A5079498848- Nanoplatforms for cancer theranostics
- Dermatologic Treatments and Research
- melanin and skin pigmentation
- Skin Protection and Aging
- Pancreatic function and diabetes
- Financial Literacy, Pension, Retirement Analysis
- Pharmaceutical industry and healthcare
- bioluminescence and chemiluminescence research
- Epigenetics and DNA Methylation
- BIM and Construction Integration
- Psychological Well-being and Life Satisfaction
- Psychological and Temporal Perspectives Research
- Autophagy in Disease and Therapy
- Pancreatic and Hepatic Oncology Research
- Construction Project Management and Performance
- Hedgehog Signaling Pathway Studies
- Advanced Manufacturing and Logistics Optimization
- Social Media in Health Education
University School
2023
Case Western Reserve University
2023
Cleveland Clinic Lerner College of Medicine
2023
University of Pittsburgh
2019
Abstract Inherited genetic variations in the melanocortin-1 receptor (MC1R) responsible for human red hair color (RHC) variants are associated with impaired DNA damage repair and increased melanoma risk. MC1R signaling is critically dependent on palmitoylation, primarily mediated by protein acyltransferase zinc finger DHHC-type palmitoyltransferase 13 (ZDHHC13). A better understanding of how ZDHHC13 physiologically activated could help identify approaches to prevent melanomagenesis redheads....
Identification and validation of new functionally relevant pharmacologically actionable targets for pancreatic ductal adenocarcinoma (PDAC) remains a great challenge. Premalignant acinar cell reprogramming (acinar-to-ductal metaplasia [ADM]) is precursor intraepithelial neoplasia (PanIN) lesions that can progress to PDAC. This study investigated the role proline-rich tyrosine kinase 2 (PYK2) in mutant Kras-induced pancreatitis-associated ADM PanIN formation, as well PDAC maintenance....
A Vision of the Future Construction Industry Hong Kong James Wong, Judy Zhang, Julian Lee Pages 1-7 (2015 Proceedings 32nd ISARC, Oulu, Finland, ISBN 978-951-758-597-2, ISSN 2413-5844) Abstract: The construction industry has been a powerful engine behind city's rapid urban development. It serves to improve living environment and standards, create connected society, promote Kong's sustainable development, enhance long-term competitiveness. To tackle manpower shortfall its efficiency, also...
<div>Abstract<p>Inherited genetic variations in the melanocortin-1 receptor (MC1R) responsible for human red hair color (RHC) variants are associated with impaired DNA damage repair and increased melanoma risk. MC1R signaling is critically dependent on palmitoylation, primarily mediated by protein acyltransferase zinc finger DHHC-type palmitoyltransferase 13 (ZDHHC13). A better understanding of how ZDHHC13 physiologically activated could help identify approaches to prevent...
<div>Abstract<p>Inherited genetic variations in the melanocortin-1 receptor (MC1R) responsible for human red hair color (RHC) variants are associated with impaired DNA damage repair and increased melanoma risk. MC1R signaling is critically dependent on palmitoylation, primarily mediated by protein acyltransferase zinc finger DHHC-type palmitoyltransferase 13 (ZDHHC13). A better understanding of how ZDHHC13 physiologically activated could help identify approaches to prevent...
<p>Figure S1-S5</p>
<p>Figure S1-S5</p>
<p>Figure S1-S5</p>
<div>Abstract<p>Inherited genetic variations in the melanocortin-1 receptor (MC1R) responsible for human red hair color (RHC) variants are associated with impaired DNA damage repair and increased melanoma risk. MC1R signaling is critically dependent on palmitoylation, primarily mediated by protein acyltransferase zinc finger DHHC-type palmitoyltransferase 13 (ZDHHC13). A better understanding of how ZDHHC13 physiologically activated could help identify approaches to prevent...
<p>Figure S1-S5</p>