Objectives: To determine whether pulse oximetry-detected episodes of desaturation are associated with impairment cerebral and somatic (renal) tissue oxygenation in mechanically ventilated preterm neonates. Design: Observational cross-sectional study. Setting: Neonatal intensive care unit a university-affiliated children's hospital. Patients: Ten (gestational age 24–32 wks) infants. Interventions: In addition to the traditional monitoring hemodynamic variables that included oximetry (Sao2),...

Angiotensin II (ANG II) has been shown to play a role in the induction of glomerular injury. In present study, we evaluated effects ANG on mesangial cell apoptosis and involved molecular mechanism.The effect mouse cells (MC) was by morphologic, DNA fragmentation TUNEL assays. To evaluate oxidative stress mechanisms, studied antioxidants, anti-TGF-beta antibody, inhibitors nitric oxide synthase modulators cytosolic calcium/heme oxygenase (HO) activity. addition, generation reactive oxygen...

Introduction: The reported rate of developing radiation pneumonitis (RP) in patients receiving definitive therapy (RT) for lung cancer is 5% to 36%. However, this incidence probably underreported because the nonspecific symptoms RP that may be erroneously attributed another cardiovascular or respiratory disorder. objective study was evaluate RT chemoradiation therapy. Methods: Of 110 were reviewed, 86 chosen a retrospective analysis. A diagnosis made based on clinical assessment first 6 12...

Objective: To evaluate the effectiveness of a breastfeeding promotion program in Women, Infant and Children (WIC) Supplemental Nutrition Program participants. Study design: This randomized clinical trial included 52 women intervention group who received one-to-one pre- postnatal education support from lactation consultant. Women (n = 52) to controls standard services. Data regarding their infants' feeding (classified as exclusive, partial, bottle) during first 7 days, 1, 2, 3 months age were...

Intraventricular hemorrhage (IVH) is a common disorder among preterm neonates that routinely diagnosed and monitored by 2D cranial ultrasound (US). The cerebral ventricles of patients with IVH often have period ventricular dilation (ventriculomegaly). This initial increase in ventricle size can either spontaneously resolve, which shows clinically as stabilization eventual decline back towards more normal size, or progressive does not stabilize may require interventional therapy to reduce...

Abstract Background Early detection and treatment of neonatal hyperbilirubinemia is important in the prevention bilirubin-induced encephalopathy. In this study, we evaluated New Jersey pediatricians' practices beliefs regarding management their compliance with recommendations made by American Academy Pediatrics (AAP) 1994. Methods A survey questionnaire was mailed to a random sample 800 pediatricians selected from list 1623 Fellows AAP initially October 2003 then February 2004 for...

Vein of Galen malformation (VOGM) is a rare congenital vascular caused by the maldevelopment its embryonic precursor, median prosencephalic vein Markowski. VOGM results in neonatal morbidity and mortality, premature delivery does not improve outcome. We report term female neonate whom was diagnosed prenatally at 37 wk gestation during growth ultrasound confirmed fetal magnetic resonance imaging. Signs cardiac decompensation were evident fetus. Multiple interventional radiology embolizations...

There are a few studies on the consequence of use breastmilk substitutes during postpartum hospital stay duration breastfeeding in culturally diverse populations United States. The main purpose this study was to identify association between in-hospital feeding pattern and infant's postdischarge modality first month life population women. Demographic, clinical, practice data collected from medical charts interviews mothers conducted after singleton delivery healthy term newborns. Among 307...

Occurrence and consequence of cord blood (CB) vitamin D insufficiency/deficiency has not been adequately explored despite rising concern regarding this topic in pediatrics. This study was designed to determine the rate, maternal risk factors, clinical outcomes infants association with insufficient/deficient status at birth. American Academy Pediatrics (AAP) defined levels (ng/mL) were utilized categorize CB samples as deficient (5–15), insufficient (16–20), sufficient (21–100). We used...

A simple method to promote the use of human milk and subsequent breast feeding in low birthweight infants was evaluated 32 babies. In 9intervention9 group (n = 16; mean (SD) weight 1559 (228) g length gestation 33.2 (1.8) weeks), were allowed suckle at when their general condition permitted after as much possible had been expressed, then given full required feeds by tube. Full started soon infant could suck adequately. Sixteen control (mean 1605 (198) 34.1 (2.4) fed conventional manner only...

The accuracy of transcutaneous bilirubin (TcB) measurements obtained with a Bilicheck device in 70 preterm neonates before phototherapy and during from the exposed unexposed skin forehead (under eye patch) was evaluated by comparing TcB total serum (TSB) that performed within ± 30 minutes measurements. correlation proportion similar, overestimated, underestimated paired TcB/TSB calculated. A TSB point estimate 1.5 mg/dL used for comparison differences between TSB. There weaker when (r =...

<h3>Objective</h3> To assess the effect of duration spontaneous hypoxic episodes and variations in haemodynamic parameters on cerebral renal tissue oxygenation (rSo₂C rSo₂R) clinically stable preterm infants. <h3>Design</h3> Observational study. <h3>Setting</h3> Neonatal intensive care unit a university-affiliated children9s hospital. <h3>Patients</h3> rSo₂C rSo₂R were recorded for 2–3 h (once or twice) neonates (n=10) using near-infrared...

A prospective observational study was conducted on 212 neonates born between 24 and 42 weeks of gestation who required blood sampling to determine total serum bilirubin (TSB) in the first week life, prior phototherapy. The transcutaneous (TcB) measurements were performed infant's forehead using BiliCheck™ within ±30 min a sample being drawn. There significant (r = 0.78) correlation levels obtained transcutaneously those measured blood. not affected by birth weight dependent levels. negative...

Objective: High susceptibility to infection and deficient cytokine production in newborns make breastmilk beneficial, especially for very preterm-born infants. This study was conducted identify the association between preterm gestation levels of pro- anti-inflammatory cytokines transitional mature during first month lactation after adjustment mode delivery parity. Study Design: Four samples (6–8, 13–15, 20–22, 27–29 days) were collected from each mother term or at gestational age less than...