A5102945615- Herpesvirus Infections and Treatments
- Asthma and respiratory diseases
- Acne and Rosacea Treatments and Effects
- Birth, Development, and Health
- Immune Cell Function and Interaction
- Neonatal Respiratory Health Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Eosinophilic Esophagitis
- Breastfeeding Practices and Influences
- Body Composition Measurement Techniques
- Estrogen and related hormone effects
- COVID-19 Clinical Research Studies
- Congenital Diaphragmatic Hernia Studies
- T-cell and Retrovirus Studies
- Sexual Differentiation and Disorders
- Allergic Rhinitis and Sensitization
- Animal Virus Infections Studies
- Cardiovascular and exercise physiology
- CAR-T cell therapy research
- Hormonal and reproductive studies
- Muscle metabolism and nutrition
- Immunotherapy and Immune Responses
- Sepsis Diagnosis and Treatment
- Virology and Viral Diseases
- Global Education and Multiculturalism
GlaxoSmithKline (United States)
2021-2025
Kerman University of Medical Sciences
2022
Institut National de la Recherche Scientifique
2012-2017
Armand Frappier Museum
2017
Uniformed Services University of the Health Sciences
2015
Islamic Azad University Central Tehran Branch
2014
University of South Carolina
2010-2013
Michigan State University
2012
David Hide Asthma and Allergy Research Centre
2012
Abstract Background There is a lack of current herpes zoster (HZ) incidence data among younger age groups immunocompetent adults in the United States (US), with rigorous exclusion criteria for potential immunocompromising (IC) or chronic conditions. Here we assess not only but also HZ severity across groups.Table 1.US IR/1000 PY by in: overall population, selected disease, and participants between January 1, 2017 to March 31, 2022 - IR: Incidence Rate. PY: Person Years at risk. CI:...
Since 2020, Chinese students studying in the United States have suffered a precipitous decline enrollment. The restrictive nature of and American student visa policies during COVID-19 impacted international students' travel admissions patterns. result was an increased number U.K. European Union. Meanwhile, parents reputation for their significant involvement influence educational decision-making domain concerning children's academic trajectories developmental pathways. This study employed...
Breastfeeding has been linked with increased forced vital capacity (FVC) in children but not older adolescents. Our aim was to investigate the effects of breastfeeding duration and infant weight gain on FVC both developmental periods. In a birth cohort, information collected at 1 2 yrs; spirometric tests were conducted 10 18 yrs. To estimate effect yrs age, we used linear models; analyse repeated measurements mixed models. Links between breastfeeding, age analysed through path analyses....
Background Immune specific genes as well regulating the formation of skin barrier are major determinants for eczema manifestation. There is a debate to whether allergic sensitization and filaggrin gene (FLG) variants lead or FLG increase risk sensitization. To investigate time-order between with respect variants, data from large prospective study covering infancy late adolescence were analyzed. Methodology/Principal Findings Repeated measurements (documented by prick tests) at ages 1, 2, 4,...
The role of breast milk on the risk childhood asthma is in dispute. aim this prospective study to determine relationship immune markers maternal serum during gestation and asthma-like symptoms (AS) infancy.Pregnant women were recruited Columbia Charleston, South Carolina. Blood (median: three weeks before delivery) (three after samples collected. Concentrations interferon (IFN)-γ, IFN gamma-induced protein 10 (IP-10 or CXCL10), CCL11, interleukin (IL) 1β, IL-4, IL-5, IL-6, CXCL8, IL-10,...
Dok-1 and Dok-2 negatively regulate responses downstream of several immune receptors in lymphoid myeloid cells. Recent evidence showed that Dok proteins are essential the formation memory CD8+ T cells to an exogenous epitope expressed by vaccinia virus; however, importance control viral infection is unknown. Here, we investigated role modulating response against herpes simplex virus 1 (HSV-1) a mouse model ocular infection. During acute infection, titers eye were similar wild-type (WT)...
Abstract Diverse signals received by CD8+ T cells are integrated to achieve the required magnitude of cell expansion and appropriate balance effector/memory generation. Notably, strength nature TCR signaling influence differentiation functional capacity effector memory cells. Dok-1 Dok-2, two members Dok family expressed in cells, negatively regulate vitro. However, role proteins modulating function vivo has not yet studied. We studied Dok-2 regulation response vaccinia virus infection....
This study investigates associations between gene expressions of aromatase (CYP19), 17α hydroxylase (CYP17), and estrogen receptors α β anthropometric measurements in offspring the Michigan fish eater cohort. Leg trunk length, height, weight, BMI expression peripheral blood cells were measured The parental generation was followed 1973 1991, maternal age, weight data collected. Female contacted 2001/2002 up 2006/2007; information included education, reproductive history, smoking, exercise....
In T cells, two members of the Dok family, Dok-1 and Dok-2, are predominantly expressed. Recent evidence suggests that they play a negative role in T-cell signaling. order to define whether proteins regulate development, we have generated transgenic mice overexpressing thymocytes peripheral cells. We show overexpression retards transition from CD4(-) CD8(-) CD4(+) CD8(+) stage. Moreover, there is specific expansion PLZF-expressing Vγ1.1(+) Vδ6.3(+) This subset γδ cells acquires innate...
Seasonal influenza poses a major public health burden worldwide. Influenza vaccines, updated yearly to match circulating strains based on World Health Organization (WHO) recommendations, are the cornerstone of prevention and require regular monitoring. The COVID-19 pandemic is expected cause logistical, site access medical staff constraints could affect safety profile vaccines. Following European Medicines Agency guidance, an enhanced surveillance (ESS) study assessed frequency severity...
This post-marketing surveillance study evaluated the safety of adjuvanted recombinant zoster vaccine (RZV) in Chinese adults, given limited country-specific data accumulated since 2019 licensure RZV China for adults ≥ 50 years age (YOA). descriptive, prospective cohort enrolled YOA who voluntarily received per routine clinical practice six centers China. The primary outcomes were occurrence, intensity, and causal relationship to vaccination medically attended adverse events (MAEs) within 30...
OBJECTIVE: To examine brain volumetric changes in individuals with single versus multiple Traumatic Brain Injuries (TBI). BACKGROUND: Repetitive Injury (TBI) has been implicated progressive neurological termed chronic traumatic encephalopathy (CTE).While histopathological findings have correlated changes, no radiological modality is available to the effect of repetitive injuries. Volumetric noted acutely post-TBI. We compared head injuries at 1 year post injury determine if there are...
Yousefi, Mitra; Karmaus, Wilfried; Zhang, Hongmei; Holloway, John; Ewart, Susan; Arshad, Hasan Author Information
Osuch, Janet; Karmaus, Wilfried; Landgraf, Jeff; Taffe, Bonita; Mikucki, Dorota; Haan, Pam; Yousefi, Mitra; Hsu, Wei-Wen Author Information