A5103211206- Coronary Interventions and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Aquaculture Nutrition and Growth
- Gout, Hyperuricemia, Uric Acid
- Inflammasome and immune disorders
- Animal Genetics and Reproduction
- Growth Hormone and Insulin-like Growth Factors
- Angiogenesis and VEGF in Cancer
- Heme Oxygenase-1 and Carbon Monoxide
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Optical Coherence Tomography Applications
- Acupuncture Treatment Research Studies
- interferon and immune responses
- Atherosclerosis and Cardiovascular Diseases
- Cytokine Signaling Pathways and Interactions
- Complementary and Alternative Medicine Studies
- Healthcare and Venom Research
- T-cell and B-cell Immunology
Harbin Medical University
2010-2023
Second Affiliated Hospital of Harbin Medical University
2010-2023
Inner Mongolia Medical University
2011
Abstract Background Elevated plasma homocysteine levels, known as hyperhomocysteinemia, have been identified an independent risk factor for atherosclerosis and related cardiovascular diseases. Macrophage pyroptosis-mediated inflammation is crucial in the development of atherosclerosis, but underlying mechanisms remain unclear. Methods A hyperhomocysteinemia atherosclerotic model with ApoE −/− mice fed a high-methionine diet was constructed to investigate role atherosclerosis. THP-1-derived...
Abstract Pyroptosis plays an important role in inflammatory diseases such as viral hepatitis and atherosclerosis. Apigenin exhibits various bioactivities, particularly anti‐inflammation, but its effect on pyroptosis remains unclear. The aim of this study is to investigate the apigenin explore potential against diseases. THP‐1 macrophages treated by lipopolysaccharides/adenosine 5′‐triphosphate were used vitro model. Western blot was detect expression NLRP3 inflammasome components key...
Coronary restenosis is a pressing challenge in cardiovascular diseases with an annual incidence of 3 – 4%. The aim the study was to assess influence known risk factors predicting coronary systematic analysis and original retrospective survey. In first stage, we performed review using Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) protocol. second searched 15,000 patients who had undergone angiography, considering identified during stage. From 516 versus 282...
<h3>Background</h3> We sought to test the feasibility of imaging vulnerable atherosclerotic plaque in vivo using optical coherence tomography (OCT) assess value rabbit model established with a novel way. <h3>Methods</h3> 30 Rabbits were randomly divided into two groups: Group A (n=15): Balloon injury carotid artery followed by high cholesterol diet (HCD) for 12 weeks. B In this group, thin filter paper slip statured 10% ferric trichloride was lay between paraffin and common infiltrated 3 5...
<h3>Objectives</h3> To investigate the neointimal coverage and malapposition of sirolimus-eluting stent in treatment CTOs non-CTO lesions (including lipid-rich plaque non-lipid-rich plaque) by optical coherence tomography. <h3>Methods</h3> We enrolled 64 patients (CTO: n=29 stents/21 patients, plaque: n=33 stents/26 n=21 stents/17 patients) with 68 target vessels examined lesion characteristics using OCT at pre- post-SES implantation 6 months follow-up. Lipid rich was defined as lipid...
<h3>Objectives</h3> To assess the frequency of peri-strut low intensity area (PLIA) in polymeric and nonpolymeric drug-eluting stents by optical coherence tomography (OCT) porcine model, to analyse pathological changes PLIA. <h3>Setting</h3> Previous intravascular ultrasound studies showed that black holes were more commonly seen sirolimus-eluting stent restenosis. Similar phenomenon (peri-strut area) was also frequently detected OCT DES follow-up. However, it is still largely unknown what...
<h3>Objectives</h3> Assess seriate progress of vulnerable plaque (VP) formation fusing Optical Coherence Tomography (OCT) with histopathological test to confirm what we find in the OCT imaging on established rabbit model. Providing early characteristics signals displayed by VP order prior recognise people, give accurate and reasonable therapy. <h3>Method</h3> 23 New Zealand white rabbits were randomly divided into 4 groups after balloon injurying intima subsequently 1% high fat diet....