A5100679422- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Pregnancy and preeclampsia studies
- Ocular Surface and Contact Lens
- Hepatitis B Virus Studies
- Coronary Interventions and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Organ Transplantation Techniques and Outcomes
- MRI in cancer diagnosis
- Inflammatory Biomarkers in Disease Prognosis
- Corneal Surgery and Treatments
- Thyroid Disorders and Treatments
- Diet and metabolism studies
- Cardiac Imaging and Diagnostics
- Medical Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Glaucoma and retinal disorders
- Aortic Disease and Treatment Approaches
- Adipokines, Inflammation, and Metabolic Diseases
- Acute Kidney Injury Research
- Diabetes Management and Research
- Ectopic Pregnancy Diagnosis and Management
- Lung Cancer Research Studies
- Pregnancy and Medication Impact
- Sympathectomy and Hyperhidrosis Treatments
Beijing YouAn Hospital
2012-2024
Capital Medical University
2012-2024
Shandong Provincial Hospital
2022-2024
Shandong First Medical University
2022-2024
Liaocheng People's Hospital
2024
National Oceanic and Atmospheric Administration
2024
Lanzhou University
2022-2024
Second Affiliated Hospital of Dalian Medical University
2022-2024
Second Hospital of Shandong University
2024
Dalian Medical University
2013-2024
Background/Aims: Obesity has become a major health concern with few effective medications. Cinnamaldehyde (CA) been reported to exhibit anti-diabetic and anti-inflammatory properties. However, whether CA shows anti-obesity activity remains unknown. Therefore, the present study aimed investigate potential effects of on mice fed high-fat diet (HFD) explore possible mechanisms involved. Methods: Male C57BL/6J an HFD for 12 weeks were supplemented (40 mg/kg/day) via gavage additional 8 weeks....
Efficacy and safety of two new formulations artificial tears in subjects with dry eye disease: a 3-month, multicenter, active-controlled, randomized trial Peter A Simmons, Haixia Liu, Cindy Carlisle-Wilcox, Joseph G Vehige Allergan Clinical Research, Allergan, Inc., Irvine, CA, USA Purpose: To evaluate compare the efficacy investigational tear (CHO-1 CHO-2) containing carmellose sodium, hyaluronic acid at different concentrations, osmoprotectants, standard sodium-containing formulation...
Purpose. This study used image analysis to compare the temporal progression and spatial reoccurrence of area tear film breakup (AB) in dry eye normal subjects. Methods. Tear was induced 10 control subjects during Staring Breakup Dynamics (S-TBUD) test, which involves keeping one open for as long possible, termed maximum blink interval (MBI). Video imaging fluorescence measured onset AB. AB location were mapped. The ABs from first trial, rate or growth (DAGR), overlap three successive trials...
ObjectiveTo develop an orthotopic, allogeneic, uterine transplantation technique and effective immunosuppressive protocol in the sheep model. MethodsIn this pilot study, 10 sexually mature ewes were subjected to laparotomy total abdominal hysterectomy with oophorectomy procure uterus allografts. The cold ischemic time was 60 min. End-to-end vascular anastomosis performed using continuous, non-interlocking sutures. Complete tissue reperfusion achieved all animals within 30 s after...
Dry eye disease is highly prevalent worldwide, causing discomfort and visual disturbances that can limit basic activities such as reading driving. Although artificial tears represent first-line therapy, there a paucity of published controlled clinical trials. The present study compared the efficacy, safety, acceptability 2 multicomponent, lipid-based tear formulations (ADV1 ADV2) to those an existing formulation (DET) in patients with signs symptoms dry disease.This 3-month, multicenter,...
The aim of this study was to evaluate the effectiveness and toxicities three-dimensional conformal radiation therapy (3DCRT), intensity-modulated (IMRT), volumetric-modulated arc (VMAT) in patients with cervical esophageal cancer. Specifically, we asked whether technological advances conferred an advantage respect clinical curative effect. Seventy-eight cancer treated definitive radiotherapy or without concomitant chemotherapy at our institution between 2007 2014 were enrolled study: 26...
Harnessing biomaterials for in vitro tissue construction has long been a research focus because of its powerful potentials engineering and pharmaceutical industry. Myocardium is critical cardiac with complex multiple muscular layers. Considering the specific characters native tissues, it necessary to design biocompatible biomimetic platform cardiomyocyte culture myocardium formation sustained physiological function. In this study, we developed gelatin-based hydrogels chemically cross-linked...
The important pathophysiological role of immune dysfunction, especially innate dysfunction in patients with acute-on-chronic liver failure (ACLF), has been investigated recent years, but dysregulation adaptive immunity remains poorly elucidated. aim this study was to (i) determine the CD3(+) T-lymphocyte count and balance between CD4(+) regulatory T (Tregs) conventional cells (Tconv) hepatitis B virus (HBV)-related ACLF patients; (ii) analyse frequencies Tregs subpopulations; (iii) assess...
Delirium is an acute mental disorder and common postoperative complication. Monitoring regional cerebral oxygen saturation (rSO2) in endovascular therapeutic surgery may allow real-time monitoring of desaturation, avoiding profound dysfunction, reducing the incidence delirium. We sought to examine delirium patients undergoing surgery. This was a clinical cohort trial (registered with http://www.clinicaltrials.gov [NCT02356133]). monitored rSO2 43 general anesthesia The occurrence after...
To evaluate effects of a novel multi-ingredient artificial tear formulation containing carboxymethylcellulose (CMC) and hyaluronic acid (HA) in murine dry eye model.Dry was induced mice (C57BL/6) using an intelligently controlled environmental system (ICES). CMC+HA (Optive Fusion™), CMC-only (Refresh Tears(®)), HA-only (Hycosan(®)) tears control phosphate-buffered saline (PBS) were administered 4 times daily compared with no treatment (n = 64 eyes per group). During regimen 1 (prevention...
Background: The objective of the study is to develop a scoring system for predicting 90-day re-exacerbation in hospitalized patients with acute exacerbations chronic obstructive pulmonary disease (AECOPD). Methods: A total 176 consecutive AECOPD were included. sociodemographic characteristics, status before exacerbation (AE), presentations and treatment current AE, 90 days after discharge from hospital collected. Results: rate was 48.9% (86 out 176). It associated degree lung function...
This study compared a new contact lens rewetting drop containing both carboxymethylcellulose and hyaluronic acid (CMC-HA) with standard only (CMC). Symptoms of discomfort typical in wear lid wiper epitheliopathy (LWE) were assessed over 3-month period diverse sample wearers.
The aim was to investigate the expression of CXCR4 protein in five molecular subtypes breast cancer. authors randomly selected cancer paraffin-embedded specimens Affiliated Third Hospital Harbin Medical University between 2007 and 2009. Details are as follows: basal-like subtype—ER (–), PR C-erbB-2 CK5/6 (+), n = 36; normal CK5/6(–), 40; luminal A subtype—ER/PR 38; B 60; (+) 58. Using immunohistochemistry method, detected subtypes. subtype highest, that lowest. In terms cancer, differences...
Elevated plasma fibrinogen levels are associated with tumor progression and poor outcomes in different cancer patients. The objective of this study was to investigate the clinical prognostic value preoperative patients operable breast cancer.Two hundred twenty-three diagnosed were retrospectively evaluated study. Plasma examined before treatment analyzed along patient clinicopathological parameters, disease-free survival (DFS) overall (OS). Both univariate multivariate analyses performed...
Radiotherapy and chemotherapy can kill tumor cells improve the survival rate of cancer patients. However, they also damage normal cause serious intestinal toxicity, leading to gastrointestinal mucositis[1]. Traditional Chinese medicine is effective in improving side effects chemotherapy. Wumei pills (WMP) was originally documented Treatise on Exogenous Febrile Diseases. It has a significant effect chronic diarrhea other diseases, but it not clear whether affects chemotherapy-induced...
This study aimed to explore the risk factors, metabolic characteristics, and potential biomarkers of mild cognitive impairment in type 2 diabetes mellitus (T2DM-MCI) provide evidence for diagnosis, prevention, treatment (MCI) patients with (T2DM).
Alzheimer's disease (AD) is a prevalent irreversible neurodegenerative condition marked by gradual cognitive deterioration and neuronal loss. The mammalian Ste20-like kinase (MST1)–Hippo pathway pivotal in regulating cell apoptosis, immune response, mitochondrial function, oxidative stress. However, the association between MST1 function AD remains unknown. Therefore, this study investigates effect of on damage impairment homeostasis AD. In study, 4- 7-month-old 5xFAD mice were selected to...