A5077641340- Adipose Tissue and Metabolism
- Ginseng Biological Effects and Applications
- Bone Metabolism and Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Gut microbiota and health
- Cancer-related molecular mechanisms research
- Higher Education and Teaching Methods
- Bone health and osteoporosis research
- Sirtuins and Resveratrol in Medicine
- Traditional Chinese Medicine Studies
- MicroRNA in disease regulation
- Advanced Computational Techniques and Applications
- Traditional Chinese Medicine Analysis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Educational Technology and Pedagogy
- Parathyroid Disorders and Treatments
- Cardiovascular Conditions and Treatments
- Natural Antidiabetic Agents Studies
- Educational Technology and Assessment
- Congenital Heart Disease Studies
- Metabolism, Diabetes, and Cancer
- Tryptophan and brain disorders
- Ideological and Political Education
- Peroxisome Proliferator-Activated Receptors
- EFL/ESL Teaching and Learning
Beijing University of Chinese Medicine
2016-2025
Xuzhou Medical College
2025
Shanghai Jiao Tong University
2025
Shanghai First People's Hospital
2025
Qilu Hospital of Shandong University
2024
Northeast Agricultural University
2024
Shanghai Ocean University
2024
Hebei University of Science and Technology
2023
Dalian University of Technology
2017-2022
Changchun University of Chinese Medicine
2011-2021
Aim. In routine histopathology, decalcification is an essential step for mineralized tissues. The purpose of this study to evaluate the effects different solutions on morphological and antigenicity preservation in Sprague Dawley (SD) rat femurs. Materials Methods. Four were employed remove mineral substances from femurs, including 10% neutral buffered EDTA, 3% nitric acid, 5% 8% hydrochloric acid/formic acid. Shaking low temperature used process samples. stainings hematoxylin-eosin (HE)...
Gut dysbiosis and oxidative stress may trigger senile osteoporosis. Fructus Ligustri Lucidi (FLL) has bone-preserving properties affects the intestinal microecology. However, mechanism of anti-osteoporotic effect FLL its link to gut microbiota remains be elucidated. Here, we demonstrated that sustained exposure ICR mice D-galactose / sodium nitrite for 90 days causes aging-related osteoporosis reduced cognitive performance. The aging phenotype is also characterized by increased in serum....
Background/Aims: Obesity has become a major health concern with few effective medications. Cinnamaldehyde (CA) been reported to exhibit anti-diabetic and anti-inflammatory properties. However, whether CA shows anti-obesity activity remains unknown. Therefore, the present study aimed investigate potential effects of on mice fed high-fat diet (HFD) explore possible mechanisms involved. Methods: Male C57BL/6J an HFD for 12 weeks were supplemented (40 mg/kg/day) via gavage additional 8 weeks....
Background: The gut microbiota plays important roles in the occurrence and development of obesity diabetes through participating nutrient absorption metabolism. Microecological regulation is likely to be key understanding effects Chinese medicine. Linggui Zhugan (LGZG) formula a well-known medicine for controlling clinic. However, its pharmacological mechanism action require further exploration. Objective: To evaluate LGZG on body weight, glycemic control, lipid levels, high-fat diet-induced...
Salvianolic acid B prevents body weight gain and improves insulin sensitivity in obese mice. The underlying mechanism behind these effects may be associated with the regulation of metabolic endotoxemia, gut microbiota homeostasis LPS/TLR4 pathway.
With the rapid development of biopharmaceutical industry, human anatomy, as a fundamental component basic medical sciences, has become increasingly important in drug development, clinical research, and evaluation. This paper explores construction practice anatomy curriculum for major, analyzing content design, innovative teaching methods, establishment assessment mechanisms. The study finds that through modular design student-centered approach, students’ understanding application anatomical...
Purpose: Increasing evidence supported that semaphorin 3A (Sema3A), insulin-like growth factor (IGF)-1 and β-catenin were involved in the development of osteoporosis diabetes. This study is aimed to evaluate whether Sema3A/IGF-1/β-catenin directly alterations bone microarchitecture strength diabetic rats. Methods: Diabetic rats induced by streptozotocin high fat diet exposure. Bone femurs evaluated micro-CT scanning, three-point bending examination stainings HE, alizarin red S safranin...
Purpose: This study is designed to explore whether Fructus ligustri lucidi (FLL) exhibits antioxidant effect in ovariectomized (OVX) rats, and identify the signaling pathway involved this process. Methods: OVX rats were treated with FLL aqueous extract (3.5 g/kg) for 12 weeks. Serum, uteri, tibias harvested from levels of total capacity (TAC), nitric oxide (NO), malondialdehyde (MDA), 8-hydroxy-desoxyguanosine (8-OHdG), superoxide dismutase (SOD) determined. Changes NF-κB-p65,...
This study was aimed at examining the effects of lycopene on bone metabolism in high-fat diet (HFD)- induced obese mice and to identify potential underlying mechanisms. Mice were fed a HFD for 12 weeks then continue with or without intervention (15 mg/kg) additional 10 weeks. The blood glucose lipid metabolism, as well serum levels total antioxidant capacity (T-AOC), superoxide dismutase (SOD), malondialdehyde (MDA) determined by biochemical assays. Bone histomorphological features...
Jiang Tang Xiao Ke (JTXK) granule, a Chinese herbal formula, has been used clinically to treat type 2 diabetes (T2DM) for decades. Our previous studies showed that JTXK granule exhibited anti-diabetic and anti-oxidative functions in experimental diabetic rats induced by high fat diet streptozotocin. However, the underlying mechanisms remain poorly understood. Herein, we aimed investigate therapeutic effect of on T2DM KKAy mice possible associations with skeletal muscle current study. results...
Purpose: Mitochondrial dysfunction in adipose tissue has emerged as key to the development of obesity and diabetes. Salvianolic acid B (SalB) is a water-soluble ingredient derived from Salvia miltiorrhiza that been shown possess potential anti-obese anti-diabetic activities. However, cellular mechanism SalB on mitochondrial function with respect these metabolic disorders not elucidated. Therefore, we aim investigate effects 3T3-L1 adipocytes analyze underlying molecular mechanism. Methods:...
Accumulating evidence suggests that mitochondrial dysfunction and adipocyte differentiation promote lipid accumulation in the development of obesity diabetes. Curcumin is an active ingredient extracted from Curcuma longa has been shown to exhibit antioxidant anti-inflammatory potency metabolic disorders. However, underlying mechanisms curcumin adipocytes remain largely unexplored. We studied effects on adipogenic oxygen consumption analysed possible mechanisms. 3T3-L1 preadipocytes were used...