- Ocular Surface and Contact Lens
- Advanced Sensor and Energy Harvesting Materials
- Glaucoma and retinal disorders
- Bone Metabolism and Diseases
- Protein Degradation and Inhibitors
- Ferroelectric and Piezoelectric Materials
- Nuclear Physics and Applications
- Radiation Detection and Scintillator Technologies
- Dielectric materials and actuators
- Peptidase Inhibition and Analysis
- Ubiquitin and proteasome pathways
- Advanced Text Analysis Techniques
- Remote Sensing and Land Use
- Health disparities and outcomes
- Intergenerational Family Dynamics and Caregiving
- Corneal Surgery and Treatments
- Advanced Materials and Mechanics
- Metabolomics and Mass Spectrometry Studies
- Cancer-related molecular mechanisms research
- Multiple Myeloma Research and Treatments
- Topic Modeling
- AI in cancer detection
- Ophthalmology and Visual Impairment Studies
- Advanced Computational Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
Xi'an Jiaotong University
2009-2025
AbbVie (United States)
2020-2025
Allergan (United States)
2015-2025
ShanghaiTech University
2021-2024
Shandong Institute of Business and Technology
2024
Qingdao Agricultural University
2023-2024
China Agricultural University
2024
Lanzhou University
2017-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024
Northwestern Polytechnical University
2024
The dorsal medial prefrontal cortex (dmPFC) has been recognized as a key cortical area for nociceptive modulation. However, the underlying neural pathway and function of specific cell types remain largely unclear. Here, we show that lesions in dmPFC induced an algesic anxious state. Using multiple tracing methods including rabies-based transsynaptic method, outlined excitatory descending from to ventrolateral periaqueductal gray (vlPAG). Specific activation dmPFC/vlPAG by optogenetic...
Abstract Self‐assembled membranes with periodic wrinkled patterns are the critical building blocks of various flexible electronics, where wrinkles usually designed and fabricated to provide distinct functionalities. These typically metallic organic materials good ductility that tolerant complex deformation. However, preparation oxide membranes, especially those intricate wrinkle patterns, is challenging due their inherently strong covalent or ionic bonding, which leads material crazing...
Depression amongst the elderly population is a worldwide public health problem, especially in China. Affected by urban–rural dual structure, depressive symptoms of urban and rural areas are significantly different. In order to compare its influencing factors among areas, we used data from fourth wave China Health Retirement Longitudinal Study (CHARLS). A total 7690 participants at age 60 or older were included this study. The results showed that there was significant difference prevalence...
Breast cancer is a prominent type with high mortality. Early detection of breast could serve to improve clinical outcomes. Ultrasonography digital imaging technique used differentiate benign and malignant tumors. Several artificial intelligence techniques have been suggested in the literature for using ultrasonography (BUS). Nowadays, particularly deep learning methods applied biomedical images achieve classification performances. This work presents new feature generation BUS images. The...
Dielectric capacitors are promising for high power energy storage, but their breakdown strength (Eb ) and density (Ue usually degrade rapidly at temperatures. Adding boron nitride (BN) nanosheets can improve the Eb high-temperature endurance with a limited Ue due to its low dielectric constant. Here, freestanding single-crystalline BaZr0.2 Ti0.8 O3 (BZT) membranes constant fabricated, introduced into BN doped polyetherimide (PEI) obtain laminated PEI-BN/BZT/PEI-BN composites. At room...
The limitation of activities daily living (ADL) affects the mental health older adults. We distinguished into basic (BADL) and instrumental (IADL) aimed to explore relationship between two limitations depressive symptoms among Chinese adults by using nationally representative cross-sectional data.
Abstract Inorganic/organic dielectric composites are very attractive for high energy density electrostatic capacitors. Usually, linear and ferroelectric materials chosen as inorganic fillers to improve storage performance. Antiferroelectric (AFE) materials, especially single‐crystalline AFE oxides, have relatively efficiency higher than dielectrics or ferroelectrics. However, adding oxides into polymers construct composite with improved performance remains elusive. In this study,...
Abstract The ultrahigh flexibility and elasticity achieved in freestanding single-crystalline ferroelectric oxide membranes have attracted much attention recently. However, for antiferroelectric oxides, the limit fundamental mechanism their are still not explored clearly. Here, we successfully fabricate PbZrO 3 by a water-soluble sacrificial layer technique. They exhibit good antiferroelectricity commensurate/incommensurate modulated microstructure. Moreover, they also shape recoverability...
Ectoine, a novel natural osmoprotectant, protects bacteria living in extreme environments. This study aimed to explore the therapeutic effect of ectoine for dry eye disease. An experimental model was created C57BL/6 mice exposed desiccating stress (DS) with untreated as controls (UT). DS were dosed topically 0.5–2.0% or vehicle control. Corneal epithelial defects detected via corneal smoothness and Oregon Green dextran (OGD) fluorescent staining. Pro-inflammatory cytokines chemokines...
China's rapid development and urbanization have created large numbers of migrant laborers, with increasing young adults couples migrating from rural areas to cities. As a result, number children become left-behind (LBC), who were left behind in their hometown cared for by one parent, grandparents, relatives or friends. Some these LBC chance be college students, are called students experience. studies indicated that the absence students' parents during childhood may cause them some mental...
AGN-190584 (Allergan, an AbbVie company) is optimized topical formulation of pilocarpine hydrochloride, 1.25%, designed for managing presbyopia and enhanced with a proprietary vehicle.
ROS-responsive Pre-PROTAC degrades BRD3 in high-ROS T47D cancer cells while remained constant normal 293T cells.
The COVID-19 pandemic has caused significant global public health challenges, and impacted HIV testing reporting worldwide. We aimed to estimate the impact of polices on identifying HIV/AIDS cases in China from 2020 2022.
To compare changes in optical quality and visual performance that accompany tear break-up (TBU) during blink suppression.A three-channel system was developed simultaneously measured refractive aberrations (Shack-Hartmann aberrometer), 20/40 letter contrast sensitivity (CS), TBU (retroillumination, RI). Ten wearers of silicone hydrogel contact lenses were asked to keep one eye open for approximately 18 seconds, while CS, wavefront aberrations, RI images collected. The reconstructed by zonal...
Oxide nanosprings have attracted many research interests because of their anticorrosion, high-temperature tolerance, oxidation resistance, and enhanced-mechanic-response from unique helix structures, enabling various applications like nanomanipulators, nanomotors, nanoswitches, sensors, energy harvesters. However, preparing oxide is a challenge for intrinsic lack elasticity. Here, an approach self-assembled, epitaxial, ferroelectric with built-in strain due to the lattice mismatch in...
Background There is currently a lack of model for predicting the occurrence venous thromboembolism (VTE) in patients with lung cancer. Machine learning (ML) techniques are being increasingly adapted use medical field because their capabilities intelligent analysis and scalability. This study aimed to develop validate ML models predict incidence VTE among cancer patients. Methods Data from Grade 3A hospital China without were included. Patient characteristics clinical predictors related...
Objectives: The purpose of this study was to explore the association between multiple chronic conditions (MCCs) and depressive symptoms among older adults in China. Methods: We used fourth round data from China Health Retirement Longitudinal Study, included 9789 aged 60 years old above. Results: Compared with without disease, MCCs those one disease had a high risk depression (MCCs: OR-adjusted: 1.55, 95% CI: 1.37 1.75; disease: 1.20, 1.05-1.37). In urban areas, prevalence 2.01 times higher...
Blueberries are recognized worldwide as one of the most important healthy foods due to their anthocyanins, which have special antioxidant properties. They become a highly produced and valuable fruit crop. Most blueberry varieties rich in impart beautiful blue color; however, there currently several with different colors worldwide, these special-colored key analyzing coloring mechanism fruit. Fruit color could be seen an nutritional quality trait terms marketing. In this study, combination...
Large low-field magnetoresistance (LFMR, < 1 T), related to the spin-disorder scattering or spin-polarized tunneling at boundaries of polycrystalline manganates, holds considerable promise for development low-power and ultrafast magnetic devices. However, achieving significant LFMR typically necessitates extremely low temperatures due diminishing spin polarization as temperature rises. To address this challenge, one strategy involves incorporating Ruddlesden-Popper structures (ABO3)n:AO,...