Yajie Guo

ORCID: 0009-0008-1361-311X
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About
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Research Areas
  • Adipose Tissue and Metabolism
  • Lung Cancer Research Studies
  • AI in cancer detection
  • Single-cell and spatial transcriptomics
  • Plant Virus Research Studies
  • Molecular Biology Techniques and Applications
  • CRISPR and Genetic Engineering
  • Estrogen and related hormone effects
  • Brain Metastases and Treatment
  • Hormonal and reproductive studies
  • Cervical Cancer and HPV Research
  • Radiomics and Machine Learning in Medical Imaging
  • Chromosomal and Genetic Variations
  • Glioma Diagnosis and Treatment
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • 3D Printing in Biomedical Research

Guangxi Medical University
2022-2024

Henan Agricultural University
2024

Cangzhou Central Hospital
2022

Breast cancer is a prominent type with high mortality. Early detection of breast could serve to improve clinical outcomes. Ultrasonography digital imaging technique used differentiate benign and malignant tumors. Several artificial intelligence techniques have been suggested in the literature for using ultrasonography (BUS). Nowadays, particularly deep learning methods applied biomedical images achieve classification performances. This work presents new feature generation BUS images. The...

10.2147/ijgm.s347491 article EN cc-by-nc International Journal of General Medicine 2022-02-28

The recent advancements in developing the CRISPR/Cas9 system and various derivative tools (e.g., base editors) have accelerated basic plant science research crop improvement by creating multiple types of genetic variations (Li et al., 2023a). However, use Cas9 protein is frequently limited requirement G/C-rich protospacer-adjacent motif (PAM) sequences, especially triticeae plants, many which are important food forage crops carrying large complex genomes. CRISPR/CasΦ (CRISPR/Cas12j) has...

10.1111/jipb.13624 article EN cc-by-nc Journal of Integrative Plant Biology 2024-02-13

Adrenal-origin and peripheral tissue-transformed 11-oxygenated androgens are recognized as significant androgens. However, our current understanding of the synthesis androgens, including organs cell types involved, remains limited.

10.1093/ejendo/lvae104 article EN PubMed 2024-09-02

Objectives Ultrasound (US) imaging is a relatively novel strategy to monitor the activity of blood–brain barrier, which can facilitate diagnosis and treatment neurovascular-related metastatic tumors. The purpose this study was investigate clinical significance applying combination US outcomes associated genes. This performed construct line drawings prediction brain metastases arising from breast cancer. Methods RNA transcript data Cancer Genome Atlas (TCGA) database obtained for cancer,...

10.3389/fneur.2022.889106 article EN cc-by Frontiers in Neurology 2022-06-20

Human fetal adrenal glands produce substantial amounts of dehydroepiandrosterone (DHEA), which is one the most important precursors sex hormones. However, underlying biological mechanism remains largely unknown. Herein, we sequenced human and gonads from 7 to 14 gestational weeks (GW) via 10× Genomics single-cell transcriptome techniques, reconstructed their location information by spatial transcriptomics. Relative gonads, begin synthesize steroids early. The coordination among steroidogenic...

10.3389/fendo.2022.1036517 article EN cc-by Frontiers in Endocrinology 2022-11-17

The human adrenal gland is composed of the cortex and medulla, which contain different function cells. aim this study was to build a 3D culture system for glands.

10.7754/clin.lab.2024.240719 article EN Clinical Laboratory 2024-01-01
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