Xiaosheng Li

ORCID: 0009-0007-4507-2488
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About
Contact & Profiles
Research Areas
  • Venous Thromboembolism Diagnosis and Management
  • Dialysis and Renal Disease Management
  • Inflammatory Biomarkers in Disease Prognosis
  • Cancer Immunotherapy and Biomarkers
  • Total Knee Arthroplasty Outcomes
  • Central Venous Catheters and Hemodialysis
  • Chronic Kidney Disease and Diabetes
  • Acute Myocardial Infarction Research
  • Shoulder Injury and Treatment
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Hepatitis C virus research
  • Muscle and Compartmental Disorders
  • Sarcoidosis and Beryllium Toxicity Research
  • Cancer-related molecular mechanisms research
  • Osteoarthritis Treatment and Mechanisms
  • Renal and related cancers
  • Chemotherapy-induced cardiotoxicity and mitigation
  • IgG4-Related and Inflammatory Diseases
  • Connective Tissue Growth Factor Research
  • Genetic and Kidney Cyst Diseases
  • Bone Metabolism and Diseases
  • Healthcare and Venom Research
  • Lipid metabolism and disorders
  • Apelin-related biomedical research
  • Angiogenesis and VEGF in Cancer

Chongqing Cancer Hospital
2022-2025

Chongqing University
2022-2025

First Affiliated Hospital of Gannan Medical University
2020-2025

Hunan Normal University
2012-2020

Hunan Provincial People's Hospital
2020

Shanghai East Hospital
2016

Huazhong University of Science and Technology
2005

Background There is currently a lack of model for predicting the occurrence venous thromboembolism (VTE) in patients with lung cancer. Machine learning (ML) techniques are being increasingly adapted use medical field because their capabilities intelligent analysis and scalability. This study aimed to develop validate ML models predict incidence VTE among cancer patients. Methods Data from Grade 3A hospital China without were included. Patient characteristics clinical predictors related...

10.3389/fcvm.2022.845210 article EN cc-by Frontiers in Cardiovascular Medicine 2022-03-07

Stomach cancer (GC) has one of the highest rates thrombosis among cancers and can lead to considerable morbidity, mortality, additional costs. However, date, there is no suitable venous thromboembolism (VTE) prediction model for gastric patients predict risk. Therefore, an urgent need establish a clinical VTE in patients. We collected data on 3092 between January 1, 2018 December 31, 2021. And after feature selection, 11 variables are reserved as predictors build model. Five machine learning...

10.1016/j.heliyon.2022.e12681 article EN cc-by-nc-nd Heliyon 2023-01-01

The prevalence and mortality rates of gastric carcinoma are disproportionately elevated in China, with the disease's intricate varied characteristics further amplifying its health impact. Precise forecasting overall survival (OS) is paramount importance for clinical management individuals afflicted this malignancy. To develop validate a nomogram model that provides precise cancer prevention treatment guidance more accurate outcome prediction patients carcinoma. Data analysis was conducted on...

10.4251/wjgo.v17.i2.95423 article EN World Journal of Gastrointestinal Oncology 2025-01-18

Background The increasing utilization of immune checkpoint inhibitors (ICIs) has led to a concomitant rise in the incidence immune-related adverse events (irAEs), notably immune-mediated colitis (IMC). This study aimed identify clinical risk factors associated with IMC development patients lung cancer and develop prediction model facilitate personalized treatment care strategies. Methods data collected included 21 variables, including sociodemographic characteristics, cancer-related factors,...

10.3389/fimmu.2025.1510053 article EN cc-by Frontiers in Immunology 2025-01-30

Immune checkpoint inhibitors (ICIs) have been widely used in various types of cancer, but they also led to a significant number adverse events, including ICI-induced immune-mediated hepatitis (IMH). This study aimed explore the risk factors for IMH patients treated with ICIs and develop validate new nomogram model predict IMH. Detailed information was collected between January 1, 2020, December 31, 2023. Univariate logistic regression analysis assess impact each clinical variable on...

10.5582/bst.2024.01351 article EN PubMed 2025-02-01

Background: This study aimed to evaluate the effect of Shenbing Decoction III (SBD III) and its key Apigenin on peritoneal dialysis (PD)–induced fibrosis explore underlying mechanisms. Methods: Liquid chromatography–mass spectrometry confirmed presence in SBD III. Human mesothelial cells (HMrSV5) were stimulated with PD solution (PDS) induce fibrosis, treatment was administered. Results: PDS decreased cell viability increased migration invasion capabilities HMrSV5 cells. It also reduced...

10.1155/jfbc/7841565 article EN cc-by Journal of Food Biochemistry 2025-01-01

Objectives: Venous thromboembolism (VTE) is a significant complication in patients with multiple myeloma (MM) that adversely affects morbidity, mortality, and treatment outcomes. This study aimed to develop validate predictive nomogram for assessing VTE risk MM using clinicopathological factors. Methods: Clinical data, including 25 candidate factors, were collected. Univariate multivariate logistic regression analyses performed identify independent factors VTE. The was constructed these...

10.3390/biomedicines13040770 article EN cc-by Biomedicines 2025-03-21

BACKGROUND Oesophageal cancer is a significant health concern worldwide, with high incidence and mortality rates. In China, the disease burden particularly high, accounting for substantial proportion of oesophageal cases related deaths worldwide. AIM To explore relationship between rate patients insurance type, out-of-pocket ratio, joint effects type ratio. METHODS The χ 2 test was used to analyze patients’ demographic clinical characteristics. Multivariate logistic regression, Cox...

10.4251/wjgo.v17.i4.103629 article EN World Journal of Gastrointestinal Oncology 2025-03-24

Abstract Objective Nasopharyngeal carcinoma (NPC) is prevailing in Southern China, characterized by distinct geographical distribution. Aimed to predict the overall survival (OS) of patients with nasopharyngeal carcinoma, this study developed and validated nomograms considering demographic variables, hematological biomarkers, oncogenic pathogens China. Methods The clinicopathological follow-up data obtained from a prospective longitudinal cohort Chongqing University Cancer Hospital between...

10.1186/s12935-022-02776-8 article EN cc-by Cancer Cell International 2022-11-19

10.1007/s00590-012-1043-7 article EN European Journal of Orthopaedic Surgery & Traumatology 2012-07-19

Background: End-stage renal disease (ESRD) is the final stage of chronic kidney (CKD). In clinic, Uremic Clearance Granules (UCG) are mainly used in treatment early CKD and stabilized function. However, benefits mechanisms UCG on ESRD remain unclear. Methods: Rats were randomly divided into four groups: sham group, model peritoneal dialysis (PD) group group. Except for sham-operated was induced by 5/6 nephrectomy other three groups. The PD then subjected to PD. addition, given gavage when...

10.2147/dddt.s364069 article EN cc-by-nc Drug Design Development and Therapy 2022-08-01

Objective The incidence and mortality of lung cancer rank first among malignant tumors, its long treatment cycle will bring serious economic burdens to patients their families. There are few studies on the prognosis insurance policies. This article explores relationship between cancer-specific death public health insurance, self-paying rate, joint effect rate. Materials Methods A prospective longitudinal cohort study was conducted in Chongqing, China from 2013 2019. selected subjects were...

10.3389/fpubh.2022.842844 article EN cc-by Frontiers in Public Health 2022-04-29

Introduction: Propylthiouracil (PTU) is commonly used to treat hyperthyroidism and can induce antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis.Although this a rare side effect, ANCA-associated vasculitis progress severe disease if its diagnosis treatment are delayed, leading poor prognosis.Case Presentation: A 43-year-old woman with Graves' developed pulmonary diffuse alveolar hemorrhage (DAH) associated ANCA against myeloperoxidase proteinase-3 that was confirmed by computed...

10.5812/ircmj.23320 article EN Iranian Red Crescent Medical Journal 2016-02-01

A simple, noninvasive method for removing peritoneal dialysis (PD) catheters, called the “pull technique,” has become popular in recent years. Physicians still worry, however, about range of its application and possible complications such as infection retained cuff breakage. We, therefore, applied this technique patients enriched administration PD catheters. Altogether, 24 catheter removals were reviewed during period from July 2018 to October 2019 our hospital. Using pull technique,...

10.1177/0896860820915022 article EN Peritoneal Dialysis International 2020-03-30

In China, lung cancer ranks first in both incidence and mortality among all malignant tumors. Non-small cell (NSCLC) constitutes the vast majority of cases, accounting for 80% to 85% cases. Immune checkpoint inhibitors (ICIs), either as monotherapies or combined with other treatments, have become standard first-line therapy NSCLC patients. This study aimed establish a nomogram model patients receiving immunotherapy incorporating demographic information, clinical characteristics, laboratory...

10.3389/fimmu.2024.1487078 article EN cc-by Frontiers in Immunology 2024-11-20

Venous thromboembolism (VTE) poses a significant threat to lung cancer patients, particularly those receiving treatment with immune checkpoint inhibitors (ICIs). We aimed develop and validate nomogram model for predicting the occurrence of VTE in patients undergoing ICI therapy.

10.1002/cam4.70115 article EN cc-by Cancer Medicine 2024-08-01

Postoperative venous thromboembolism (VTE) is a potentially life-threatening complication. This study aimed to develop predictive model identify independent risk factors and estimate the likelihood of VTE in patients undergoing surgery for cervical cancer.

10.1186/s12957-024-03649-2 article EN cc-by-nc-nd World Journal of Surgical Oncology 2024-12-31

Background The mechanism of Venous thromboembolism (VTE) is complicated and difficult to prevent due factors such as bone marrow invasion, therapy, immune-mediated effects. This study aims establish a nomogram model for predicting the risk thrombosis in lymphoma patients undergoing chemotherapy, which has been increasing over past 30 years.

10.1080/07853890.2023.2275665 article EN cc-by-nc Annals of Medicine 2023-12-12

Diabetes mellitus is a common chronic disease. This study aimed to investigate the correlation between serum insulin-like growth factor 1 receptor (IGF-1R), vascular endothelial (VEGF), endothelin (ET) levels, and bone mineral density (BMD) in type 2 diabetic (T2DM) patients treated with metformin plus α-glucosidase inhibitors evaluate predictive value of factors prognosis osteoporosis these patients. It was prospective that enrolled 142 T2DM Dinghu District People's Hospital from March 2019...

10.1155/2022/7707875 article EN Evidence-based Complementary and Alternative Medicine 2022-04-21
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